Results 81 to 90 of about 32,619 (226)

Studies on the bound nucleotide of muscle fibrils [PDF]

, 1963
The possibility was investigated that phosphorus uptake from ATP or uptake of ATP molecules by the muscle proteins occurs during contraction and relaxation of rabbit myofibrils.
Temperley, Eileen
core  

Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy. [PDF]

, 2017
Transverse (T)-tubules make-up a specialized network of tubulated muscle cell membranes involved in excitation-contraction coupling for power of contraction. Little is known about how T-tubules maintain highly organized structures and contacts throughout
Fujita, Naonobu, Fukuda, Mitsunori, Groulx, Jean-Francois, Huang, Wilson, Jean, Steve, Kiger, Amy A, Koyama-Honda, Ikuko, Kuchitsu, Yoshihiko, Lin, Tzu-Han, Mizushima, Noboru, Nguyen, Jen   +10 more
core   +2 more sources

ULTRASTRUCTURAL FEATURES OF CARDIOMYOCYTE CONTRACTILE APPARATUS IN RAT OFFSPRING HEARTS FOLLOWING MATERNAL CHRONIC ALCOHOL INTOXICATION

Проблеми екології та медицини
Background. The mechanisms underlying the development of the heart contractile apparatus and the distribution of myofibrils in cardiomyocytes following intrauterine ethanol intoxication continue to be a topic of significant debate.
I.V. Tverdokhlib, D.G. Marchenko
doaj   +1 more source

Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes. [PDF]

, 2018
Serine/threonine protein phosphatase 5 (PP5) is ubiquitously expressed in eukaryotic cells; however, its function in cardiomyocytes is unknown. Under basal conditions, PP5 is autoinhibited, but enzymatic activity rises upon binding of specific factors ...
Beckendorf, Lisa, Boknik, Peter, Dos Remedios, Cris G, Gergs, Ulrich, Hamdani, Nazha, Krysiak, Judith, Linke, Wolfgang A, Redfield, Margaret M, Sheikh, Farah, Unger, Andreas, von Frieling-Salewsky, Marion   +10 more
core   +3 more sources

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Polarization-resolved microscopy reveals a muscle myosin motor-independent mechanism of molecular actin ordering during sarcomere maturation.

PLoS Biology, 2018
Sarcomeres are stereotyped force-producing mini-machines of striated muscles. Each sarcomere contains a pseudocrystalline order of bipolar actin and myosin filaments, which are linked by titin filaments.
Olivier Loison, Manuela Weitkunat, Aynur Kaya-Çopur, Camila Nascimento Alves, Till Matzat, Maria L Spletter, Stefan Luschnig, Sophie Brasselet, Pierre-François Lenne, Frank Schnorrer   +9 more
doaj   +1 more source

Specific Staining of Muscle Cytoskeletal Proteins in Litopenaeus vannamei and Their Role in Textural Deterioration during Refrigeration [PDF]

Shipin Kexue
To clarify the key material basis for the rapid softening of shrimp muscle during refrigeration, this study established a specific histological detection method for cytoskeletal proteins and analyzed the correlation between the degradation of ...
CAI Peifeng, LIAO Weilong, FENG Jun, HU Li, LI Caihong, XU Defeng
doaj   +1 more source

Examination of the Effects of Heterogeneous Organization of RyR Clusters, Myofibrils and Mitochondria on Ca2+ Release Patterns in Cardiomyocytes [PDF]

, 2015
Spatio-temporal dynamics of intracellular calcium, [Ca2+]i, regulate the contractile function of cardiac muscle cells. Measuring [Ca2+]i flux is central to the study of mechanisms that underlie both normal cardiac function and calcium-dependent ...
A Baddeley, A Hatano, A Hatano, A Zahradnikova, AM Katz, Amorita Petzer, Anthony Hickey, AT Roe, AW Trafford, B Sportisse, BD Ripley, C Bradley, C Pinali, C Pinali, C Soeller, C Soeller, C Soeller, C Soeller, Cameron G. Walker, Christian Soeller, D Baddeley, D Baddeley, D Eisner, Daniel A Beard, David J. Crossman, DJ Greensmith, DM Bers, DM Bers, DR Laver, E Picht, E Theakston, EA Sobie, Edmund J. Crampin, F Brette, F Brette, F Legros, FR Heinzel, GD Smith, Gregory Bass, GSB Williams, GSB Williams, H Si, ID Jayasinghe, ID Jayasinghe, ID Jayasinghe, II Dorn, Ivo Siekmann, J Hake, J Hake, J Illian, J Moller, J Okada, JR Kremer, K Gusev, L Biesmans, L Boyman, L Zhang, LS Song, LS Song, LT Izu, M Vendelin, Mark H. Ellisman, Masahiko Hoshijima, MB Cannell, MD Stern, MD Stern, MH Ellisman, PC Bressloff, PM Kekenes-Huskey, R Turner, S Svensson, S-Q Wang, T Das, T Hayashi, T Hong, V Piacentino, Vijay Rajagopal, WE Louch, X Lu, Y Cheng, Y Hou   +80 more
core   +6 more sources

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Effects of Protein Kinase A on the Phosphorylation Status and Transverse Stiffness of Cardiac Myofibrils

Journal of Pharmacological Sciences, 2013
Stimulation of β-adrenergic receptors in cardiac myocytes activates cyclic AMP– dependent protein kinase A (PKA). PKA-mediated phosphorylation of myofibrils decreases their longitudinal stiffness, but its effect on transverse stiffness is not fully ...
Yoshiki Ohnuki, Takenori Yamada, Yasumasa Mototani, Daisuke Umeki, Kouichi Shiozawa, Takayuki Fujita, Yasutake Saeki, Satoshi Okumura   +7 more
doaj   +1 more source