Results 221 to 230 of about 380,707 (403)

Myosin & Myosin-family Proteins - II [PDF]

Biophysical Journal, 2008
openaire   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

Editorial: Hypertrophic Cardiomyopathy and Precision Medicine in Cardiovascular Disease. [PDF]

Med Sci Monit
Parums DV.
europepmc   +1 more source

-304-BIOCHEMICAL EVALUATION OF INTRACORONARY THROMBOLYSIS BY PLASMA CREATINE PHOSPHOKINASE AND SERUM CARDIAC MYOSIN LIGHT CHAIN

, 1986
Mitsuaki Isobe, Ryozo Nagai, Yoshio Yazaki, Hideaki Nakaoka, Fumimaro Takaku, Tetsu Yamaguchi, Hiroki Kurihara, Masakiyo Nobuyoshi, Akira Seki   +8 more
openalex   +2 more sources

Ileal bile acid transporter inhibitors in Alagille syndrome and Progressive Familial Intrahepatic Cholestasis: A systematic review into dose–response

British Journal of Clinical Pharmacology, EarlyView.
Ileal bile acid transporter inhibitors (IBATi), including maralixibat and odevixibat, are a novel approach to the treatment of paediatric cholestatic liver diseases, such as Alagille syndrome (ALGS) and different forms of progressive familial intrahepatic cholestasis (PFIC).
Alise D. E. de Groot, Cristina Chiadò, Jos G. W. Kosterink, Willem S. Lexmond, Paola Mian, Henkjan J. Verkade   +5 more
wiley   +1 more source

Myosin-9 is required for lysosome-mediated nonlytic reovirus egress. [PDF]

PLoS Pathog
Fernández de Castro I, Sachse M, Taylor GM, Fernández JJ, Tenorio R, Fernández-Sánchez SY, Dermody TS, Risco C.   +7 more
europepmc   +1 more source

Force‐velocity properties of human skeletal muscle fibres: myosin heavy chain isoform and temperature dependence.

, 1996
Roberto Bottinelli, Monica Canepari, Maria Antonietta Pellegrino, Carlo Reggiani   +3 more
openalex   +2 more sources

Insights into the myosin II inhibitory potency of A-ring-modified (S)-blebbistatin analogs [PDF]

, 2017
Bracke, Marc, Roman, Bart, Stevens, Christian, Van den broecke, Tom, Verhasselt, Sigrid   +4 more
core   +2 more sources

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence for regulatory science and innovation in pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo, Iain Frater, Rebecca Kuruvilla, Stefanie Lip, Hannah O'Neill, Kerry Burke, Vicky Chaplin, Alexander S. F. Doney, Salim Elyas, Nicholas Greaves, Sophie Harding, David Hargroves, Judith Hayward, Dyfrig A. Hughes, Tom A. T. Hughes, Sree Kondapally, Patrick Mok, Aaron Peace, Imran Rafi, Simon Ray, Vicky Stinton, Luigi Venetucci, Munir Pirmohamed   +22 more
wiley   +1 more source