Results 221 to 230 of about 161,523 (294)

Editorial: State-of-the-art muscle physiology research: from single molecules and cells to living organisms. [PDF]

Front Physiol
Fukuda N, Suzuki M, Oyama K, Liu N.
europepmc   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

Microscale velocity-dependent unbinding generates a macroscale performance-efficiency tradeoff in actomyosin systems. [PDF]

Commun Biol
McGrath J, Kent B, Johnson CL, Alvarado J.   +3 more
europepmc   +1 more source

Myosin Myopathies [PDF]

Biophysical Journal, 2015
openaire   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

Swinging lever mechanism of myosin directly shown by time-resolved cryo-EM. [PDF]

Nature
Klebl DP, McMillan SN, Risi C, Forgacs E, Virok B, Atherton JL, Harris SA, Stofella M, Winkelmann DA, Sobott F, Galkin VE, Knight PJ, Muench SP, Scarff CA, White HD.   +14 more
europepmc   +1 more source

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira, Julia Theisen, Katharina J. Ermer, Marie Oertel, Anton Xu, David Weissman, Katharina Ecker, Jan Dudek, Martin Fassnacht, Alexander Nickel, Michael Kohlhaas, Christoph Maack, Ulrich Dischinger   +12 more
wiley   +1 more source

Odevixibat therapy in progressive familial intrahepatic cholestasis with MYO5B variants: a retrospective case series. [PDF]

Orphanet J Rare Dis
Roquelaure B, Sciveres M, Grammatikopoulos T, Lurz E, Freudenberg F, Habes D, Thevathasan L, Elaraki F, Gonzales E.   +8 more
europepmc   +1 more source

Activation of Myosin Adenosine Triphosphatase by Carbonyl Cyanide p-Chlorophenylhydrazone

, 1964
J.J. Blum, D.R. Sanadi
openalex   +1 more source

Chicken Primordial Germ Cell Surface Marker. [PDF]

Animals (Basel)
Gough TJ, Wise TG, Bruce MP, Doran TJ, Layton DS, Bean AGD.   +5 more
europepmc   +1 more source