Results 51 to 60 of about 443 (149)

Predation Strategies of the Portuguese Man‐of‐War Physalia physalis

Marine Ecology, Volume 46, Issue 6, November/December 2025.
ABSTRACT The Portuguese man‐of‐war Physalia physalis is widely known for causing poisoning on human beings. Physalia physalis is mostly described as a predator of fish eggs and larvae. Here, we report for the first time that large fish can also be preyed by P. physalis.
Jorge L. S. Nunes, Diego S. Campos, Héllida Negrão Dias, Luiz P. N. e Silva, Denise M. R. F. Bastos, Tommaso Giarrizzo, Allan Jamesson Silva de Jesus, Jamerson Aguiar‐Santos, Ana Catarina Miranda   +8 more
wiley   +1 more source

Melatonin Activates AMPK Pathway to Regulate the Regeneration of Slow Muscle Fibers in Skeletal Muscle Injury Repair

The FASEB Journal, Volume 39, Issue 20, 31 October 2025.
The figure illustrates in vitro (melatonin‐treated C2C12 myoblasts) and in vivo (mouse frostbite‐induced tibialis anterior muscle injury with melatonin administration) models. Melatonin activates AMPK, which phosphorylates PGC‐1α to enhance mitochondrial bioenergetics (decreased ROS and LDH, increased ATP, mtDNA, membrane potential, and oxygen ...
Wei Xie, Zhengchao Hong, Yuxin Xie, Kangyan Hou, Songhan Li, Mingxin Fang, Yupeng Guan, Zhixuan Zhang, Miao Zhang   +8 more
wiley   +1 more source

Geographic variation in the clinical features of Mohave rattlesnake (Crotalus scutulatus) envenomations reported to the North American Snakebite Registry

Toxicon: X
The geographic variation of Mohave rattlesnake (Crotalus scutulatus) venom is well established. We reviewed all the Mohave rattlesnake bites reported to the Toxicology Investigators Consortium's North American Snakebite Registry between January 1, 2015 ...
Spencer Greene, Matthew Gilbert, Brian Wolk, Sharan Campleman, Anne-Michelle Ruha   +4 more
doaj   +1 more source

Serum Proteinogram in the Free‐Living Brazilian Common Opossum (Didelphis aurita)

ELECTROPHORESIS, Volume 46, Issue 18, Page 1447-1454, September 2025.
ABSTRACT Didelphis aurita is a synanthropic marsupial widely distributed in southeastern Brazil, known for its resistance to venom and its relevance in biomedical research. This study aimed to characterize the serum proteinogram of free‐living D. aurita individuals.
Andrés Mauricio Ortega Orozco, Lucas Drumond Bento, Pollyanna Cordeiro Souto, Fabrícia Modolo Girardi, Verônica Rodrigues Castro, João Vitor Gonçalves de Oliveira, Camilo José Ramirez Lopez, Edvaldo Barros, Artur Kanadani Campos, Leandro Abreu da Fonseca   +9 more
wiley   +1 more source

Antitumor potential of the myotoxin BthTX-I from Bothrops jararacussu snake venom: evaluation of cell cycle alterations and death mechanisms induced in tumor cell lines

Journal of Venomous Animals and Toxins including Tropical Diseases, 2015
Background Phospholipases A 2 (PLA 2 s) are abundant components of snake venoms that have been extensively studied due to their pharmacological and pathophysiological effects on living organisms.
Cássio Prinholato da Silva, Tássia R. Costa, Raquel M. Alves Paiva, Adélia C. O. Cintra, Danilo L. Menaldo, Lusânia M. Greggi Antunes, Suely V. Sampaio   +6 more
doaj   +1 more source

Efficacy of Mitochondrial Transfer in Healing Toxin‐Induced Damage to Neuromuscular Junction, an Empirical Study

Synapse, Volume 79, Issue 4, July 2025.
A neuromuscular junction (NMJ) imaged with pre‐ and postsynaptic features seen with immunofluorescent staining along with confocal microscopy. The article presented here confirms the importance of regaining proper posttraumatic NMJ structure to enable reestablishment of healthy skeletal muscle mass and how the presence of mitochondrial matter promotes ...
Michael R. Deschenes, Max Rackley, Sophie Fernandez, Megan Heidebrecht, Kate Hamilton, Hector G. Paez, Christopher Pitzer, Stephen E. Alway   +7 more
wiley   +1 more source

Overexpression of enhanced yellow fluorescent protein fused with Channelrhodopsin‐2 causes contractile dysfunction in skeletal muscle

The FASEB Journal, Volume 38, Issue 22, 30 November 2024.
Optogenetic tools like Channelrhodpsin‐2 (ChR2) are useful for inducing skeletal muscle contraction using blue light. However, the prevalence of fluorescent proteins like EYFP may cause functional issues. Here, Lamia et al. showed that the contractile properties of ChR2‐EYFP skeletal muscle had aggregated EYFP in sarcolemma, decreased contractile force
Syeda N. Lamia, Carol S. Davis, Peter C. D. Macpherson, T. Brad Willingham, Yingfan Zhang, Chengyu Liu, Leanne Iannucci, Elahe Ganji, Desmond Harden, Iman Bhattacharya, Adam C. Abraham, Susan V. Brooks, Brian Glancy, Megan L. Killian   +13 more
wiley   +1 more source

Cigarette smoke exposure impairs early‐stage recovery from lengthening contraction‐induced muscle injury in male mice

Physiological Reports, Volume 12, Issue 18, September 2024.
Abstract The use of tobacco cigarettes produces locomotor muscle weakness and fatigue intolerance. Also, smokers and chronic obstructive pulmonary disease patients have a greater incidence of muscle injury and a deficient myogenic response. However, the effects of smoke exposure on the recovery from eccentric exercise‐induced muscle injuries are ...
Nicole E. Stevens, Mafalda Loreti, Israel Ramirez‐Sanchez, Felipe C. G. Dos Reis, Alessandra Sacco, Ellen C. Breen, Leonardo Nogueira   +6 more
wiley   +1 more source

Snake venom toxins: Potential anticancer therapeutics

Journal of Applied Toxicology, Volume 44, Issue 5, Page 666-685, May 2024.
Abstract Snake venom contains a cocktail of compounds dominated by proteins and peptides, which make up the toxin. The toxin components of snake venom attack several targets in the human body including the neuromuscular system, kidney and blood coagulation system and cause pathologies. As such, the venom toxins can be managed and used for the treatment
Benedict C. Offor, Lizelle A. Piater
wiley   +1 more source

Manual Therapy Exerts Local Anti‐Inflammatory Effects Through Neutrophil Clearance

Journal of Immunology Research, Volume 2024, Issue 1, 2024.
Background: Manual therapy (MT) has been widely used in China to treat local tissue inflammation for a long time. However, there is a lack of scientific evidence for using MT in anti‐inflammatory therapy, and its anti‐inflammatory mechanism needs further clarification.
Hongwen Liu, Shiguo Yuan, Kai Zheng, Gaofeng Liu, Junhua Li, Baofei Ye, Yangkun Wang, Li Yin, Yikai Li, Liu Jinhui   +9 more
wiley   +1 more source