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Immunometabolism of Liver Xenotransplantation and Prospective Solutions
Advanced Science, Volume 12, Issue 9, March 6, 2025.After xenotransplantation, pig livers will replace those of human patients to maintain the stability of metabolism and immune system. The incompatibility of immunometabolism between humans and pigs induces rejection, inflammation, coagulation dysfunction, and liver failure. The profile of immunometabolism pre‐transplantation and post‐transplantation is
Shoulong Deng +4 more
wiley +1 more source
The essential malaria protein PfCyRPA targets glycans to invade erythrocytes
Cell ReportsSummary: Plasmodium falciparum is a human-adapted apicomplexan parasite that causes the most dangerous form of malaria. P. falciparum cysteine-rich protective antigen (PfCyRPA) is an invasion complex protein essential for erythrocyte invasion.
Christopher J. Day +20 more
doaj +1 more source
Glyco-biomarkers: Potential determinants of cellular physiology and pathology [PDF]
, 2008 Once dismissed as just the icing on the cake, sugar molecules are emerging as vital components in life’s intricate machinery. Our understanding of their function within the context of the proteins and lipids to which they are attached has matured rapidly,
Alavi, A, Axford, JS
core +2 more sources
Sustainable Food Proteins, Volume 3, Issue 1, March 2025.Impact of filtration optimization on the efficiency and recovery of bioactive peptides and oligosaccharides. ABSTRACT Bovine colostrum whey permeate, a byproduct of commercial ultrafiltration for protein isolation, contains bioactive peptides and prebiotic oligosaccharides.
Andrea J. C. Tam +6 more
wiley +1 more source
The role of genetically engineered pigs in xenotransplantation research [PDF]
, 2015 There is a critical shortage in the number of deceased human organs that become available for the purposes of clinical transplantation. This problem might be resolved by the transplantation of organs from pigs genetically engineered to protect them from ...
Ayares, David +4 more
core +1 more source
Frontiers in Oncology, 2012 N-glycolylneuraminic acid (NeuGc) is a sialic acid molecule usually found in mammalian cells as terminal constituents of different membrane glycoconjugates such as gangliosides. The NeuGcGM3 ganglioside has been described as a tumor antigen for non-small
Valeria I Segatori +4 more
doaj +1 more source
A comparative study of free oligosaccharides in the milk of domestic animals [PDF]
, 2014 This study was conducted to provide a comprehensive analysis of the oligosaccharides in the milk of a variety of important domestic animals including cow, goat, sheep, pig, horse, and dromedary camel.
Al Busadah, Khalid A. +6 more
core +2 more sources
Structure of carbohydrate chain of a thrombin-like protease from the venom of Agkistrodon halys brevicaudus stejneger snake [PDF]
, 2009 The structure of the carbohydrate chain of kangshuanmei, a thrombin-like serine protease isolated from Agkistrodon halys brevicaudus stejneger snake venom, was determined. The carbohydrate content of the kangshuanmei was 18%.
Jangprasert Panchalee +7 more
core
B4GALNT2 and xenotransplantation: A newly appreciated xenogeneic antigen [PDF]
, 2018 Analysis of non-Gal antibody induced after pig-to-baboon cardiac xenotransplantation identified the glycan produced by porcine beta-1,4-N-acetyl-galactosaminyltransferase 2 (B4GALNT2) as an immunogenic xenotransplantation antigen.
Ahmad-Villiers, S +3 more
core +1 more source
Molecules, 2019 The animal product hazard factor N-glycolylneuraminic (Neu5Gc) and brain nutrient substance N-acetylneuraminic acid (Neu5Ac) were studied at the M062X/6-311 + G(d,p) geometry optimization level.
Rui Chang, Bowen Yang, Qiu-Jin Zhu
doaj +1 more source