Results 121 to 130 of about 4,874 (195)

Analysis on the terahertz spectral characteristics of two types of sialic acids in solid state and aqueous solution

Scientific Reports
In this study, N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc) were chosen as representative sialic acids to study their terahertz (THz) spectral characteristics in solid and aqueous states.
Zhuang Peng, Yang Gao, Xinrui Zhang, Huiyu Yang, Bo Su, Kai Li, Cunlin Zhang   +6 more
doaj   +1 more source

Assessment of Sialic Acid Content in Dairy Products from Buffalo’s and Goat’s Milk Compared to Cow’s Milk

Dairy
Sialic acids (SIAs) are bioactive compounds present in glycoproteins and glycolipids, playing key roles in human physiology. N-acetylneuraminic acid (Neu5Ac), the only sialic acid synthesized by humans, contributes to neurodevelopment and immune function,
Simona Rinaldi, Michela Contò, Carlo Boselli, Giuliano Palocci, Angelo Citro, Sebastiana Failla   +5 more
doaj   +1 more source

N-glycolylneuraminic acid conjugates: implications of their absence in mammalian biochemistry.

Indian journal of biochemistry & biophysics, 2012
N-glycolylneuraminic acid (Neu5Gc) is one of the two most common forms of sialic acids present in glycoproteins and glycolipids of mammalian tissues. It is synthesized from the most ubiquitous sialic acid, N-acetylneuraminic acid (Neu5Ac) in a hydroxylation reaction catalysed by the enzyme Neu5Ac hydroxylase.
Daniel W, Mwangi, Devi D, Bansal
openaire   +1 more source

Aptamer-CRISPR/Cas12a-Based Lateral Flow Technique for Visualized Rapid Detection of Endogenous Damage Factor Neu5Gc in Red Meat

Foods
The N-glycolylneuraminic acid (Neu5Gc), a major salivary acid molecule found on the cell surface of animals such as pigs, cows, and sheep, can be metabolically incorporated into the body through consumption of animal-derived foods like red meat.
Yuxi Guo, Honglin Ren, Han Wang, Xuepeng Duan, Shuaihao Qi, Xi Yang, Chunyi Shangguan, Haosong Li, Yansong Li, Pan Hu, Qiang Lu, Shiying Lu   +11 more
doaj   +1 more source

Characterization of an Aptamer Targeting Neu5Gc, as an Endogenous Pathogenic Factor Derived from Red Meat

Molecules
N-glycolylneuraminic acid (Neu5Gc), a sialic acid predominantly found in the non-neurohumoral fluids of hind-mouthed animals, is incapable of synthesizing Neu5Gc due to a deletion in the CMAH exon of the gene encoding human CMP-Neu5Gc hydroxylase.
Yuxi Guo, Honglin Ren, Han Wang, Yiran Xiao, Cong Wang, Mengdi Liu, Fuchun Duan, Haosong Li, Pan Hu, Yansong Li, Zengshan Liu, Shiying Lu   +11 more
doaj   +1 more source

Loss of N-glycolylneuraminic acid in human evolution. Implications for sialic acid recognition by siglecs.

The Journal of biological chemistry, 2000
The common sialic acids of mammalian cells are N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc). Humans are an exception, because of a mutation in CMP-sialic acid hydroxylase, which occurred after our common ancestor with great apes.
E C, Brinkman-Van der Linden, E R, Sjoberg, L R, Juneja, P R, Crocker, N, Varki, A, Varki   +5 more
openaire   +1 more source

Serological Assessment of Alpha Galactosidase, N-Glycolylneuraminic Acid, and Histopathological Observations in Xenograft Recipients. [PDF]

Cureus
Ramesh B, Ramanan S, Srimurugan B, Fakoya AO.   +3 more
europepmc   +1 more source

Intestine specific regulation of pig cytidine-5'-monophospho-N-acetylneuraminic acid hydroxylase gene for N-glycolylneuraminic acid biosynthesis. [PDF]

Sci Rep, 2019
Song KH, Kwak CH, Chung TW, Ha SH, Park JY, Ha KT, Cho SH, Lee YC, Kim CH.   +8 more
europepmc   +1 more source

N-glycolylneuraminic acid knockout reduces erythrocyte sequestration and thromboxane elaboration in an ex vivo pig-to-human xenoperfusion model. [PDF]

Xenotransplantation, 2017
Cimeno A, Hassanein W, French BM, Powell JM, Burdorf L, Goloubeva O, Cheng X, Parsell DM, Ramsoondar J, Kuravi K, Vaught T, Uluer MC, Redding E, O'Neill N, Laird C, Hershfeld A, Tatarov I, Thomas K, Ayares D, Azimzadeh AM, Pierson RN, Barth RN, LaMattina JC.   +22 more
europepmc   +1 more source

N-glycolylneuraminic acid on human epithelial cells prevents entry of influenza A viruses that possess N-glycolylneuraminic acid binding ability. [PDF]

J Virol, 2014
Takahashi T, Takano M, Kurebayashi Y, Masuda M, Kawagishi S, Takaguchi M, Yamanaka T, Minami A, Otsubo T, Ikeda K, Suzuki T.   +10 more
europepmc   +1 more source