Results 81 to 90 of about 4,874 (195)
Advanced Science, Volume 12, Issue 38, October 13, 2025.This study presents a comprehensive data mining strategy for in‐depth extraction of overall and altered glycan features from structural and site‐specific glycoproteome data across various biomedical samples. The strategy enables the uncovery of four major altered glycan features associated with thymic involution and reveals their coordinated ...
Zhida Zhang +11 more
wiley +1 more source
iMetaOmics, Volume 2, Issue 3, September 2025.This study has elucidated the role of three swine acute diarrhea syndrome coronavirus (SADS‐CoV) accessory proteins in influencing viral pathogenicity and preliminarily explored the host molecular targets and pathways affected by the NS3a, NS7a, and NS7b proteins of SADS‐CoV.
Xiaoling Yan +7 more
wiley +1 more source
Exposure to nonmicrobial N-glycolylneuraminic acid protects farmers' children against airway inflammation and colitis [PDF]
Journal of Allergy and Clinical Immunology, 2018 Childhood exposure to a farm environment has been shown to protect against the development of inflammatory diseases, such as allergy, asthma, and inflammatory bowel disease.We sought to investigate whether both exposure to microbes and exposure to structures of nonmicrobial origin, such as the sialic acid N-glycolylneuraminic acid (Neu5Gc), might play ...
Remo Frei +65 more
openaire +7 more sources
Gangliosides of human, bovine, and rabbit plasma
Journal of Lipid Research, 1972 Gangliosides were isolated from human, bovine, and rabbit plasma and were quantified by gas–liquid chromatography. Purification was achieved by sequential use of partitioning in solvents, DEAE-Sephadex chromatography, base treatment, and silicic acid ...
Robert K. Yu, Robert W. Ledeen
doaj +1 more source
Mechanisms linking colorectal cancer to the consumption of (processed) red meat : a review [PDF]
, 2015 Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the world. The vast majority of CRC cases have been linked to environmental causes rather than to heritable genetic changes.
De Smet, Stefaan +3 more
core +2 more sources
Journal of Separation Science, Volume 48, Issue 9, September 2025.ABSTRACT Ion exchange chromatography (IEC) hyphenated to mass spectrometry (MS) is a powerful non‐denaturing technique used for analyzing protein charge heterogeneity (including posttranslational modifications such as deamidation, phosphorylation, and sialylation), as well as for characterizing complex protein mixtures. This review provides an overview
Ziran Zhai +3 more
wiley +1 more source
BiomoleculesN-Glycolylneuraminic acid (Neu5Gc) is a sialic acid variant commonly found in most mammals but not synthesized by humans due to an inactivating mutation in the CMP-Neu5Ac hydroxylase (CMAH) gene. Despite this, Neu5Gc-containing molecules are consistently
Rancés Blanco, Juan P. Muñoz
doaj +1 more source
Molecular recognition of gangliosides and their potential for cancer immunotherapies
Frontiers in Immunology, 2014 Gangliosides are sialic acid-containing glycosphingolipids expressed on all vertebrate cells. They are primarily positioned in the plasma membrane, with the ceramide part anchored in the membrane and the glycan part exposed on the surface of the cell ...
Ute eKrengel, Paula A Bousquet
doaj +1 more source
Sialic acid acquisition in bacteria - one substrate many transporters [PDF]
, 2016 The sialic acids are a family of 9-carbon sugar acids found predominantly on the cell-surface glycans of humans and other animals within the Deuterostomes and are also used in the biology of a wide range of bacteria that often live in association with ...
Thomas, Gavin Hugh
core +1 more source
The milk metabolome and its potential utilisation for enhanced dairy processing
International Journal of Dairy Technology, Volume 78, Issue 3, July–September 2025.The milk metabolome can be affected by a variety of different intrinsic and extrinsic factors, which can subsequently affect important parameters of milk quality and processability. This review explores this relationship and provides an overview of the topic of milk metabolomics as an ever‐evolving field of study.
Paula Rojas‐Gómez +5 more
wiley +1 more source