Exploratory study on the role of Clonorchis sinensis infection in promoting cholangiocarcinoma progression [PDF]
Parasites & VectorsBackground Clonorchiasis, a neglected tropical zoonosis, is caused by chronic infection with Clonorchis sinensis (C. sinensis). This infection can lead to cholangitis, bile duct epithelial hyperplasia, periductal fibrosis, and cholangiocarcinoma (CCA ...
Shitao Li +12 more
doaj +2 more sources
Enhancing Catalytic Removal of N-Nitrosodimethylamine from Drinking Water Matrices with One-Step-Carbonized Ferric Ammonium Citrate [PDF]
NanomaterialsN-Nitrosodimethylamine (NDMA) is a widely recognized disinfection by-product that poses significant carcinogenic risks in drinking water. Conventional methods for NDMA removal, such as nanofiltration and reverse osmosis membranes, have limited efficacy ...
Jing Lv +8 more
doaj +2 more sources
Antioxidant properties of Ferulago angulata and its hepatoprotective effect against N-nitrosodimethylamine-induced oxidative stress in rats [PDF]
Pharmaceutical Biology, 2017 Context: Ferulago angulata (Schlecht.) Boiss. (Apiaceae) (FASB) is used to treat liver diseases and has been used both as food and therapeutics by many cultures for thousands of years because of the natural antioxidant compounds.
Hatice Kiziltas +6 more
doaj +2 more sources
Attenuation of N-nitrosodimethylamine induced hepatotoxicity by Operculina turpethum in Swiss Albino mice [PDF]
Iranian Journal of Basic Medical Sciences, 2014 Objective(s): To appraise the antihepatotoxic efficacy of ethanolic extract of Operculum turpethum root on the liver of Swiss albino mice. Materials and Methods: Hepatic fibrosis was induced in adult male albino mice through intraperitoneal ...
Veena Sharma, Manu Singh
doaj +1 more source
Comprehensive Assessment of Nitrosamine Formation in Meat Products Using UHPLC-HRMS: Analytical Challenges and Potential Dietary Implications [PDF]
MoleculesNitrosamines (NAs) pose a risk due to their carcinogenic properties, especially in processed and cured meats where nitrites and nitrates are widely used.
Tiziana Nardin +4 more
doaj +2 more sources
A Robust and Universal LC-MS/MS Method for Determination of N-Nitrosodimethylamine in Pharmaceuticals Using a C30 Column. [PDF]
J Sep SciABSTRACT Since the 2018 valsartan recall, the genotoxic impurity N‐nitrosodimethylamine (NDMA) has been frequently detected in various pharmaceuticals. Matrix variability often complicates routine testing, requiring customized analyses. We developed a universal LC–MS/MS method enabling consistent NDMA detection across diverse pharmaceuticals ...
An B +9 more
europepmc +2 more sources
Dietary exposure to N-nitrosamines and their precursors: an age-stratified assessment [PDF]
Scientific ReportsDietary exposure to N-nitrosamines (N-NAs) may pose health concerns across all age groups, particularly in children and the elderly, due to their association with increased cancer risk.
Aida Zapico +5 more
doaj +2 more sources
Distribution and health risk assessment of N-nitrosodimethylamine in urban drinking water in China
环境与职业医学, 2021 BackgroundNitrosamines, especially N-nitrosodimethylamine (NDMA), are highly carcinogenic and frequently detected in drinking water systems in China, indicating potential human health risk through drinking water.ObjectiveThis study aims to analyze the ...
Hongquan CAI +3 more
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N-nitrosodimethylamine (NDMA) and some prescribed medicines: A mini-review
International Journal of Medicine and Health Development, 2022 Recently, there have been notices of drug recalls by different pharmaceutical companies. This is based on the finding of high level of N-nitrosodimethylamine (NDMA) in such medications.
Chidiebere V Ugwueze +5 more
doaj +1 more source
Health risk assessment of N-nitrosodimethylamine in drinking water in Nanjing, Jiangsu Province
环境与职业医学, 2022 BackgroundN-nitrosodimethylamine (NDMA), a new disinfection by-product in drinking water, has attracted extensive attention due to its high detection rate and concentration.
Yuhong ZHENG +4 more
doaj +1 more source