Results 21 to 30 of about 2,628 (167)

Advanced Glycation End Products and Nitrosamines in Sausages Influenced by Processing Parameters, Food Additives and Fat during Thermal Processing

Foods, 2023
Advanced glycation end products (AGEs) and nitrosamines (NAs) in sausage are associated with pathogenic and carcinogenic risks. However, the multiple reaction parameters affecting the production of AGEs and NAs during sausage processing remain unclear ...
Jingnan Lu, Mingyu Li, Mingyue Shen, Jianhua Xie, Mingyong Xie   +4 more
doaj   +1 more source

Application of chromatographic techniques in the analysis of total nitrosamines in water

Heliyon, 2020
The use of ozone, chloramine and chlorine dioxide for water treatment results in the formation N-nitrosamines in the treated water. These groups of chemicals and other nitrogen-containing compounds have been described as disinfection by-products (DBPs ...
Abdulrazaq Yahaya, Damilola Babatunde, Lamidi W.B. Olaniyan, Oluranti Agboola   +3 more
doaj   +1 more source

OCCURRENCE OF VOLATILE NITROSAMINES IN EDIBLE OILS [PDF]

Assiut Veterinary Medical Journal, 1989
A limited survey of edible oils was undertaken to determine the presence of volatile N-nitrosamines, a class of compounds carcinogenic to a broad range of animal species. Nitrosamines were detected and quantitated by a gas liquid chromatograph interfaced
M.R.A. RASHWAN, M.K. MOUSTAFA, A A-H. AHMED   +2 more
doaj   +1 more source

Determination of dimethylamine and nitrite in pharmaceuticals by ion chromatography to assess the likelihood of nitrosamine formation

Heliyon, 2021
Since July 2018 several drugs have been recalled due to contamination with N-nitrosodimethylamine (NDMA), a probable human carcinogen. Dimethylamine (DMA) and nitrite are precursors in the formation of NDMA. In this study, ion chromatography (IC) methods
Jingli Hu, Terri Christison, Jeffrey Rohrer   +2 more
doaj   +1 more source

Salmonella typhimurium TA100 and TA1535 and E. coli WP2 uvrA are highly sensitive to detect the mutagenicity of short Alkyl-N-Nitrosamines in the Bacterial Reverse Mutation Test

Toxicology Reports, 2022
Humans are exposed to low levels of N-nitrosamines via different sources. N-Nitrosamines have recently been detected as impurities in various marketed drugs and they are known mutagenic carcinogens belonging to the cohort of concern as referred to in the
Frank Bringezu, Stephanie Simon
doaj   +1 more source

Syringic and ascorbic acids prevent NDMA-induced pulmonary fibrogenesis, inflammation, apoptosis, and oxidative stress through the regulation of PI3K-Akt/PKB-mTOR-PTEN signaling pathway

Metabolism Open, 2022
Idiopathic lung fibrosis (ILF) is a severe and life threatening lung disorder that is characterized by scarring of lung tissue, leading to thickening and stiffening of affected areas.
Oluwatobi T. Somade, Olubisi E. Adeyi, Babajide O. Ajayi, Osiro O. Asunde, Precious D. Iloh, Adedayo A. Adesanya, Olanrewaju I. Babalola, Oluwaseyi T. Folorunsho, Deborah A. Olakunle, Opeyemi F. Lawal   +9 more
doaj   +1 more source

Effect of celery powder as an alternative nitrite source on some quality properties and nitrosamine formation in sucuk [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2023
This study aimed to determine the effects of celery powder (nitrate converted to nitrite) and cooking time on the formation of nitrosamine in sucuk. The microbiological and physicochemical properties were also investigated.
Zeynep Feyza YILMAZ ORAL
doaj   +1 more source

Naturally occurring emerging contaminants: Where to hide?

HydroResearch, 2023
Water disinfection by-products (DBPs) are among insitu-generated emerging contaminants (ECs) during water disinfection. Although water disinfectants control acute risks through destruction of water-borne pathogens, the produced DBPs are associated to ...
Hossein Miraji, Mureithi Eunice, Asha Ripanda, Faustin Ngassapa, Othman Chande   +4 more
doaj   +1 more source

Sustainability in Analytical Chemistry Illustrated by Pharmaceutical Nitrosamine Testing. [PDF]

Electrophoresis
ABSTRACT Following the valsartan scandal in 2018, the testing of drug substances and drug products for N‐nitrosamines has become a critical and mandatory quality control measure. The European Pharmacopoeia chapter 2.5.42 currently describes three analytical methods for this purpose: HPLC–MS/MS, GC–MS, and GC–MS/MS.
Bredendiek F, Schmidtsdorff S, Parr MK.
europepmc   +2 more sources

Presence of nitrosamine impurities in medicinal products

Arhiv za Higijenu Rada i Toksikologiju, 2021
In 2018, some sartan medicinal products were reported to be contaminated with nitrosamine compounds, which are potent mutagenic carcinogens. Two nitrosamines received particular attention: N -nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA ...
Sedlo Ilijana, Kolonić Teo, Tomić Siniša   +2 more
doaj   +1 more source