Results 111 to 120 of about 20,037 (157)

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

open access: yesCell Proliferation, Volume 59, Issue 8, August 2026.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik   +10 more
wiley   +1 more source

Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity

open access: yesImmunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha   +2 more
wiley   +1 more source

Profiles and roles of N6-methyladenosine modification in bovine oocyte maturation. [PDF]

open access: yesBMC Genomics
Han T   +9 more
europepmc   +1 more source

Eine Universelle Nukleosid‐zu‐Nukleosid‐5′‐triphosphat‐Enzymkaskade angetrieben durch Polyphosphat

open access: yesAngewandte Chemie, Volume 138, Issue 31, 27 July 2026.
Nukleosid‐5′‐Triphosphate (NTPs) sind wichtige Bausteine für Nukleinsäuren. Ihre chemische Synthese ist aufgrund der geringen Ausbeute der 5′‐Triphosphorylierungsreaktion nur wenig effizient. Wir stellen hier eine universelle, durch Polyphosphat angetriebene Zwei‐Enzym‐Kaskade vor, die eine direkte Phosphorylierung von Nukleosiden zu NTPs ermöglicht ...
Jonathan P. Suess   +1 more
wiley   +1 more source

Dynamic modulation of N6-methyladenosine by ionizing radiation in human cells. [PDF]

open access: yesBiochem Biophys Rep
Cruz-Garcia L   +6 more
europepmc   +1 more source

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