Results 31 to 40 of about 65,196 (347)
Reversible positioning of single molecules inside zero-mode waveguides [PDF]
, 2014 We have developed a hybrid nanopore/zero-mode waveguide device for single-molecule fluorescence and DNA sequencing applications. The device is a freestanding solid-state membrane with sub-5 nm nanopores that reversibly delivers individual biomolecules to
Foquet, Mathieu +4 more
core +2 more sources
Graphene Nanopores for Protein Sequencing [PDF]
Biophysical Journal, 2016 An inexpensive, reliable method for protein sequencing is essential to unraveling the biological mechanisms governing cellular behavior and disease. Current protein sequencing methods suffer from limitations associated with the size of proteins that can be sequenced, the time, and the cost of the sequencing procedures. This study reports the results of
Wilson, James +3 more
openaire +3 more sources
From squiggle to basepair: computational approaches for improving nanopore sequencing read accuracy
Genome Biology, 2018 Nanopore sequencing is a rapidly maturing technology delivering long reads in real time on a portable instrument at low cost. Not surprisingly, the community has rapidly taken up this new way of sequencing and has used it successfully for a variety of ...
Franka J. Rang +2 more
doaj +1 more source
NanoSTR: A method for detection of target short tandem repeats based on nanopore sequencing data
Frontiers in Molecular Biosciences, 2023 Short tandem repeats (STRs) are widely present in the human genome. Studies have confirmed that STRs are associated with more than 30 diseases, and they have also been used in forensic identification and paternity testing.
Jidong Lang +4 more
doaj +1 more source
Detailed evaluation of data analysis tools for subtyping of bacterial isolates based on whole genome sequencing : Neisseria meningitidis as a proof of concept [PDF]
, 2019 Whole genome sequencing is increasingly recognized as the most informative approach for characterization of bacterial isolates. Success of the routine use of this technology in public health laboratories depends on the availability of well-characterized ...
Bertrand, Sophie +5 more
core +1 more source
Application of Nanopore Sequencing for High Throughput Genotyping in Horses
Animals, 2023 Nanopore sequencing is a third-generation biopolymer sequencing technique that relies on monitoring the changes in an electrical current that occur as nucleic acids are passed through a protein nanopore.
Artur Gurgul +6 more
doaj +1 more source
Models and information-theoretic bounds for nanopore sequencing
, 2018 Nanopore sequencing is an emerging new technology for sequencing DNA, which can read long fragments of DNA (~50,000 bases) in contrast to most current short-read sequencing technologies which can only read hundreds of bases. While nanopore sequencers can
Diggavi, Suhas +2 more
core +1 more source
, 2018 Nanopore sequencing technology has the potential to render other sequencing technologies obsolete with its ability to generate long reads and provide portability.
Alkan, Can +4 more
core +2 more sources
F1000Research, 2018 Background: The introduction of the MinION sequencing device by Oxford Nanopore Technologies may greatly accelerate whole genome sequencing. Nanopore sequence data offers great potential for de novo assembly of complex genomes without using other ...
Michael Liem +9 more
doaj +1 more source
Correlation Dynamics and Enhanced Signals for Serial DNA Sequencing
, 2013 Nanopore based sequencing has demonstrated significant potential for the development of fast, accurate, and cost-efficient fingerprinting techniques for next generation molecular detection and sequencing.
Ahmed, Towfiq +5 more
core +1 more source