Results 11 to 20 of about 19,623 (229)
Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review
Molecules, 2023 This review describes the various innovative approaches implemented for naringin extraction as well as the recent developments in the field. Naringin was assessed in terms of its structure, chemical composition, and potential food sources.
Rafeeya Shams +2 more
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Exploring the toxic mechanism of excessive intake of naringin on drug-induced liver injury using network toxicology and experiment validation strategy [PDF]
BMC Pharmacology and ToxicologyBackground Excessive intake of citrus fruits may affect liver metabolism and trigger various adverse reactions. Naringin, a natural flavonoid compound, is mainly extracted from the citrus fruits.
Yu Ding +5 more
doaj +2 more sources
Microbial Metabolism of Naringin and the Impact on Antioxidant Capacity
Nutrients, 2022 Naringin is a dietary flavonoid glycoside with broad bioactivities, and it has been found to undergo extensive microbial metabolism in human gut. Microbial metabolites are believed to play an important role in the overall bioactivity of naringin. However, knowledge is scarce about its microbial metabolism in laboratory rats, which are the most commonly
Xuan Zeng, Yuying Zheng, Weiwei Su
exaly +3 more sources
The Genoprotective Role of Naringin [PDF]
Biomolecules, 2020 Since ancient times, fruits and edible plants have played a special role in the human diet for enhancing health and maintaining youthfulness. The aim of our work was to determine the interactions between naringin, a natural ingredient of grapefruits, and DNA using an electrochemical biosensor.
Oskar Szczepaniak +6 more
openaire +3 more sources
Foods, 2022 Naringin is the major polyphenol in bitter orange peel with antioxidant property. However, its pH sensitivity, low solubility, and bitter taste limit its application in food. In this study, naringin–sodium alginate–silk fibroin microspheres were prepared
Hongyue Wang +6 more
doaj +1 more source
Food Chemistry: X, 2022 Naringin is potential functional and therapeutic ingredient, has low bioavailability because of poor aqueous solubility. In this study, an ovalbumin (OVA)-carboxymethyl konjac glucomannan (CKGM) nano-delivery system was developed to enhance the ...
Weimin Tang +7 more
doaj +1 more source
Investigation of the interaction of naringin palmitate with bovine serum albumin: spectroscopic analysis and molecular docking. [PDF]
PLoS ONE, 2013 BackgroundBovine serum albumin (BSA) contains high affinity binding sites for several endogenous and exogenous compounds and has been used to replace human serum albumin (HSA), as these two compounds share a similar structure.
Xia Zhang +6 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Naringin has been shown to exert protective effects in an animal model of ulcerative colitis, but detailed mechanisms remain unclear. This study aimed to investigate function and signaling mechanisms underlying naringin-induced therapeutic effects on ...
Jianyi Dong +10 more
doaj +1 more source
Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction. [PDF]
PLoS ONE, 2015 Naringin, a flavanone glycoside extracted from Citrus grandis Osbeck, has a wide range of pharmacological effects. In the present study we aimed at demonstrating the protective effect of naringin against diabetic kidney disease (DKD) and elucidating its ...
Fenqin Chen +6 more
doaj +1 more source
Naringin Interferes Doxorubicin-Induced Myocardial Injury by Promoting the Expression of ECHS1
Frontiers in Pharmacology, 2022 Doxorubicin (DOX) leads to myocardial cell damage and irreversible heart failure, which limits the clinical application of DOX. Naringin has biological functions of inhibiting inflammation, oxidative stress and apoptosis.
Zirui Zhao +15 more
doaj +1 more source