Results 31 to 40 of about 226,818 (311)

The role of natural killer cells in Parkinson’s disease

Experimental and Molecular Medicine, 2020
Parkinson’s disease: How natural killer cells can help Understanding the roles that inflammation and immune cells called natural killer (NK) cells play in Parkinson’s disease (PD) may help in finding new treatments.
Rachael H. Earls, Jae-Kyung Lee
doaj   +1 more source

Antiviral treatment alters the frequency of activating and inhibitory receptor-expressing natural killer cells in chronic Hepatitis B virus infected patients [PDF]

, 2012
Natural killer (NK) cells play a critical role in innate antiviral immunity, but little is known about the impact of antiviral therapy on the frequency of NK cell subsets.
Chi, X., Hou, J., Hu, X., Jin, Q., Lv, J., Niu, J., Pan, Y., Sun, H., Tian, Z., Tu, Z., Xiao, W., Xu, D., Yan, H.   +12 more
core   +3 more sources

Present and future of allogeneic natural killer cell therapy

Frontiers in Immunology, 2015
Natural killer (NK) cells are innate lymphocytes that are capable of eliminating tumor cells and are therefore used for cancer therapy. Although many early investigators used autologous NK cells, including lymphokine-activated killer cells, the clinical ...
Okjae eLim, Mi Young eJung, Yu Kyeong eHwang, Eui-Cheol eShin   +3 more
doaj   +1 more source

Resistance to cytotoxicity and sustained release of interleukin-6 and interleukin-8 in the presence of decreased interferon-γ after differentiation of glioblastoma by human natural killer cells. [PDF]

, 2016
Natural killer (NK) cells are functionally suppressed in the glioblastoma multiforme (GBM) tumor microenvironment. We have recently shown that survival and differentiation of cancer stem-like cells (CSCs)/poorly differentiated tumors are controlled ...
Bui, Vickie T, Cacalano, Nicholas, Inagaki, Akihito, Jewett, Anahid, Kasahara, Noriyuki, Kaur, Kawaljit, Kozlowska, Anna K, Topchyan, Paytsar, Tseng, Han-Ching   +8 more
core   +1 more source

Regulatory functions of natural killer cells in multiple sclerosis

Frontiers in Immunology, 2016
There is increasing evidence that natural killer (NK) cells exhibit regulatory features. Among them, CD56bright natural killer cells have been suggested to play a major role in controlling T-cell responses and maintaining homeostasis.
Catharina C. Gross, Andreas Schulte-Mecklenbeck, Heinz Wiendl, Emanuela Marcenaro, Nicole Kerlero de Rosbo, Antonio Uccelli, Antonio Uccelli, Antonio Uccelli, Alice Laroni, Alice Laroni, Alice Laroni   +10 more
doaj   +1 more source

Effector Functions of Natural Killer Cell Subsets in the Control of Hematological Malignancies. [PDF]

, 2015
Treatment of hematological malignant disorders has been improved over the last years, but high relapse rate mainly attributable to the presence of minimal residual disease still persists.
Biassoni, Biron, Björklund, Brodin, Bryceson, Burns, Campbell, Cooley, Cooper, Cooper, Curti, Davies, Di Santo, Di Santo, Farag, Fehniger, Fogler, Foley, Freud, Gasser, Gilfillan, Grimm, Guethlein, Herberman, Huntington, Joncker, Kiessling, Killig, King, Kröger, Lajoie, Lanier, Leong, Ljunggren, Lowe, Lundqvist, Mancusi, McQueen, Miller, Moretta, Moretta, Moretta, Nguyen, Oevermann, Ouyang, Perussia, Phillips, Romagnani, Romee, Rosenberg, Rosenberg, Rosenberg, Ruggeri, Santoni, Stabile, Stabile, Stern, Stringaris, Thielens, Torelli, Trinchieri, Trinchieri, Vago, Valés-Gómez, Venstrom, Vivier, Whitelaw, Zorn   +67 more
core   +1 more source

Natural Killer Cell-Based Immunotherapy for Cancer: Advances and Prospects

Engineering, 2019
Natural killer (NK) cells are key innate immune cells that provide the first line of defense against viral infection and cancer. Although NK cells can discriminate between “self” and “non-self,” recognize abnormal cells, and eliminate transformed cells ...
Yuan Hu, Zhigang Tian, Cai Zhang
doaj   +1 more source

Current state of NK cell-mediated immunotherapy in chronic lymphocytic leukemia

Frontiers in Oncology, 2023
Chronic lymphocytic leukemia (CLL) has become one of the most common hematological diseases in western countries, with an annual incidence of 42/100,000.
Zong-Han Wang, Wei Li, Hao Dong, Fujun Han   +3 more
doaj   +1 more source

Memory NK cell features exploitable in anticancer immunotherapy [PDF]

, 2019
Besides their innate ability to rapidly produce effector cytokines and kill virus-infected or transformed cells, natural killer (NK) cells display a strong capability to adapt to environmental modifications and to differentiate into long-lived ...
Battella, Simone, Capuano, Cristina, Galandrini, Ricciarda, Palmieri, Gabriella, Pighi, Chiara, Santoni, Angela   +5 more
core   +2 more sources

Characterization of natural killer cells in tamarins: a technical basis for studies of innate immunity

Frontiers in Microbiology, 2010
Natural killer (NK) cells are capable of regulating viral infection without major histocompatibility complex restriction. Hepatitis C is caused by chronic infection with hepatitis C virus (HCV), and impaired activity of NK cells may contribute to the ...
Tomoyuki eYoshida, Tomoyuki eYoshida, Akatsuki eSaito, Akatsuki eSaito, Yuki eIwasaki, Yuki eIwasaki, Sayuki eIijima, Terue eKurosawa, Yuko eKatakai, Yasuhiro eYasutomi, Keith A Reimann, Toshiyuki eHayakawa, Hirofumi eAkari, Hirofumi eAkari   +13 more
doaj   +1 more source