Results 171 to 180 of about 107,878,294 (207)
Specific NDM-1 Inhibitor of Isoliquiritin Enhances the Activity of Meropenem Against NDM-1-Positive Enterobacteriaceae in Vitro [PDF]
International Journal of Environmental Research and Public Health, 2020 NDM-1-positive Enterobacteriaceae have caused serious clinical infections, with high mortality rates. Carbapenem was the ultimate expectation for the treatment of such infections in clinical practice. However, since the discovery of plasmid-mediated New Delhi metallo-β-lactamase-1 (NDM-1), the efficient therapeutic effects of carbapenems have been ...
Xuming Deng, Jianfeng Wang, Dacheng Wang
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Journal of Biomolecular Structure and Dynamics, 2019 The discovery of NDM-1 and its variants has caused the emergence of antibiotic resistance in the community and hospital setting, causing major concern for health care across the globe.
Asad Ullah Khan +2 more
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The Lancet Infectious Diseases, 2012
The dissemination of members of the Enterobacteriaceae family with extended spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs) has become a global concern. ESBLs and MBLs have been reported in humans, domestic animals, wildlife and the environment, and their isolation frequencies are increasing rapidly worldwide. Most studies have been
Badrul, Hasan +4 more
+7 more sources
The dissemination of members of the Enterobacteriaceae family with extended spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs) has become a global concern. ESBLs and MBLs have been reported in humans, domestic animals, wildlife and the environment, and their isolation frequencies are increasing rapidly worldwide. Most studies have been
Badrul, Hasan +4 more
+7 more sources
Recent research and development of NDM-1 inhibitors
European Journal of Medicinal Chemistry, 2021Bacteria carrying New Delhi metallo-β-lactamase-1 (New Delhi metallo-β-lactamase, NDM-1) resistance gene is a new type of "superbug", which can hydrolyze almost all β-lactam antibiotics, rapidly spread among the same species and even spread among different species. NDM-1 belongs to the class B1 broad-spectrum enzyme of β-lactamase.
Ting, Wang +5 more
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The Dissemination of NDM-1 in Acinetobacter baumannii Strains
Current Microbiology, 2022Acinetobacter baumannii is a common pathogen in hospitals and usually causes bacteremia, pneumonia, meningitis, peritonitis and other diseases. Isolates carried NDM-1 gene can make several antibiotics such as carbapenems and other beta-lactams ineffective. Nowadays, the number of A.
Na, Liu +4 more
openaire +2 more sources
Balkan NDM-1: escape or transplant?
The Lancet Infectious Diseases, 2011164 www.thelancet.com/infection Vol 11 March 2011 4 Sadetzki S, Chetrit A, Lubina A, et al. Risk of thyroid cancer after childhood exposure to ionizing radiation for tinea capitis. J Clin Endocrinol Metab 2006; 91: 4798–04. 5 Boaventura P, Bastos J, Pereira D, et al.
Livermore, David M. +3 more
openaire +5 more sources
International Journal of Antimicrobial Agents, 2012 The global spread of New Delhi metallo-beta-lactamase (NDM) is of significant public health concern. This study sought to determine whether bla(NDM) was present in Enterobacteriaceae isolates displaying resistance to carbapenems that were submitted to ...
Hanna E. Sidjabat +2 more
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The spread and acquisition of NDM-1: a multifactorial problem
Expert Review of Anti-infective Therapy, 2013bla NDM is a major mechanism of resistance of Gram-negative bacteria to β-lactam antibiotics including the carbapenems. bla NDM has been acquired by a large range of Gram-negative bacilli, especially by the Enterobacteriaceae and Acinetobacter spp. The combination of human factors (suboptimal antibiotic stewardship and infection control, movement of ...
Wailan, Alexander M., Paterson, David L.
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Deciphering the Role of V88L Substitution in NDM-24 Metallo-β-Lactamase [PDF]
Catalysts, 2019 The New Delhi metallo-β-lactamase-1 (NDM-1) is a typical carbapenemase and plays a crucial role in antibiotic-resistance bacterial infection. Phylogenetic analysis, performed on known NDM-variants, classified NDM enzymes in seven clusters.
Zhihai Liu, Yang Wang, Jianzhong Shen
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Discovery of NDM-1 Inhibitors From Natural Products
Journal of Global Antimicrobial Resistance, 2019 Human health is seriously threatened by metallo-β-lactamase (MBL)-mediated bacterial antimicrobial resistance, among which New Delhi metallo-β-lactamase 1 (NDM-1) has received great attention due to its extensive substrate profile and high lateral gene transfer.
Bin Xiao, Heng Zheng
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