Results 11 to 20 of about 63,496 (250)

Metallo-Beta-Lactamases: NDM

Journal of Education, Health and Sport, 2019
New Delhi, an enzyme belonging to the Metallo-beta-lactamases and Carbapenemases group, is most commonly found in Klebsiella pneumoniae and Escherichia coli. It determines these bacteria resistance to the majority of known antibiotics.
Kamil Leis, Ewelina Mazur, Paweł Szyperski, Patryk Kaczor, Michalina Kolan, Bartłomiej Wiśniewski, Magdalena Jabłońska, Aleksandra Kulczyńska, Aleksandra Baska, Jakub Kazik, Daria Bojczuk, Klaudyna Grzelakowska, Krystian Kałużny, Przemysław Gałązka   +13 more
doaj   +6 more sources

First identification of novel NDM carbapenemase, NDM-7, in Escherichia coli in France. [PDF]

PLoS ONE, 2013
BACKGROUND: The NDM-1 carbapenemase has been identified in 2008 in Enterobacteriaceae. Since then, several reports have emphasized its rapid dissemination throughout the world.
Gaelle Cuzon, Rémy A Bonnin, Patrice Nordmann   +2 more
doaj   +4 more sources

NDM-9 resistance to taniborbactam.

The Lancet Infectious Diseases, 2023
C. Le Terrier, Virginia Gruenig, C. Fournier, P. Nordmann, Laurent Poirel   +4 more
semanticscholar   +3 more sources

Author Correction: A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation

Scientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Sohaib Nizami, Val Millar, Kanisa Arunasalam, Tryfon Zarganes-Tzitzikas, David Brough, Gary Tresadern, Paul E. Brennan, John B. Davis, Daniel Ebner, Elena Di Daniel   +9 more
doaj   +1 more source

Genomic transmission analysis of multidrug-resistant Gram-negative bacteria within a newborn unit of a Kenyan tertiary hospital: A four-month prospective colonization study

Frontiers in Cellular and Infection Microbiology, 2022
ObjectiveMultidrug-resistant organisms (MDRO), especially carbapenem-resistant organisms (CRO), represent a threat for newborns. This study investigates the colonization prevalence of these pathogens in a newborn unit at a Kenyan tertiary hospital in an ...
David Villinger, David Villinger, David Villinger, Tilman G. Schultze, Tilman G. Schultze, Tilman G. Schultze, Victor M. Musyoki, Irene Inwani, Jalemba Aluvaala, Lydia Okutoyi, Anna-Henriette Ziegler, Imke Wieters, Imke Wieters, Christoph Stephan, Christoph Stephan, Beatrice Museve, Volkhard A. J. Kempf, Volkhard A. J. Kempf, Volkhard A. J. Kempf, Moses Masika   +19 more
doaj   +1 more source

The uncertain role of substandard and falsified medicines in the emergence and spread of antimicrobial resistance

Nature Communications, 2023
Approximately 10% of antimicrobials used by humans in low- and middle-income countries are estimated to be substandard or falsified. In addition to their negative impact on morbidity and mortality, they may also be important drivers of antimicrobial ...
Sean Cavany, Stella Nanyonga, Cathrin Hauk, Cherry Lim, Joel Tarning, Benn Sartorius, Christiane Dolecek, Céline Caillet, Paul N. Newton, Ben S. Cooper   +9 more
doaj   +1 more source

Emergence and rapid dissemination of highly resistant NDM-14-producing Klebsiella pneumoniae ST147, France, 2022

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2023
Background Since 2021, an emergence of New Delhi metallo-β-lactamase (NDM)-14-producing Klebsiella pneumoniae has been identified in France. This variant with increased carbapenemase activity was not previously detected in Enterobacterales.
C. Emeraud, A. Mahamat, A. Jousset, Sandrine Bernabeu, Tania Goncalves, Camille Pommier, D. Girlich, Aurélien Birer, C. Rodriguez, J. Pawlotsky, T. Naas, R. Bonnin, L. Dortet   +12 more
semanticscholar   +1 more source

The First Experience of Combined Use of Cefepime/Sulbactam and Aztreonam in ICU Patients with Nosocomial Infections Caused by Carbapenem-Resistant Gram-Negative Microorganisms Producing Class B and D Carbapenemases

Антибиотики и Химиотерапия, 2023
Background. The difficulties of antibacterial therapy of infections caused by carbapenemase-producing  gram-negative bacteria are associated with limited options for adequate therapy since, in addition to resistance to carbapenems and other beta-lactams ...
M. P. Suvorova, I. N. Sychev, O. V. Ignatenko, E. N. Burmistrova, S. S. Mirzakhamidova, L. V. Fedina, R. M. Vakolyuk, S. V. Yakovlev   +7 more
doaj   +1 more source

New boronate drugs and evolving NDM-mediated beta-lactam resistance

Antimicrobial Agents and Chemotherapy, 2023
Taniborbactam and xeruborbactam are dual serine-/metallo-beta-lactamase inhibitors (BLIs) based on a cyclic boronic acid pharmacophore that undergo clinical development.
O. Lomovskaya, Ruslan Tsivkovski, M. Totrov, Dana C. Dressel, M. Castanheira, M. Dudley   +5 more
semanticscholar   +1 more source

The Changing Epidemiology of Carbapenemase-Producing Enterobacterales

Rambam Maimonides Medical Journal, 2022
Objective Israeli hospitals were confronted with a major national outbreak of carbapenemase-producing Enterobacterales (CPE) starting in 2006, caused predominantly by monoclonal Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae ...
Khetam Hussein, Yuval Geffen, Orna Eluk, Sigal Warman, Worood Aboalheja, Tamar Alon, Ibrahim Firan, Mical Paul   +7 more
doaj   +1 more source