Results 31 to 40 of about 63,496 (250)

High Prevalence and Diversity Characteristics of bla NDM, mcr, and bla ESBLs Harboring Multidrug-Resistant Escherichia coli From Chicken, Pig, and Cattle in China

Frontiers in Cellular and Infection Microbiology, 2022
The objective of this study was to understand the diversity characteristics of ESBL-producing Escherichia coli (ESBL-EC) in chicken, pig, and cattle. A high prevalence of ESBL-EC (260/344) was observed in all food animals with prevalence rates of 78.6 ...
Zhihai Liu, Ke Wang, Yaru Zhang, Lining Xia, Li Zhao, Changmei Guo, Xudong Liu, Liting Qin, Zhihui Hao   +8 more
semanticscholar   +1 more source

Clonal Diversity and High Prevalence of Oxa-23 among Carbapenem-Resistant Acinetobacter baumannii Isolates in Egypt [PDF]

Journal of Bioscience and Applied Research, 2019
Background and Aim: Carbapenem-resistant Acinetobacter baumannii (CRAB) is becoming a global threat especially to hospitalized patients. We aimed to address the magnitude of CRAB causing healthcare-associated infections in patients admitted to a tertiary
Nevine Fam, Doaa Gamal, Dalia Salem, Heba Dahroug, Reham Wasfy, Myriam Morcos   +5 more
doaj   +1 more source

Draft genome sequence of the blaOXA-436- and blaNDM-1-harboring Shewanella putrefaciens SA70 isolate [PDF]

, 2017
We sequenced a carbapenem-resistant Shewanella putrefaciens isolate cultured from the sink handle of a Pakistan hospital room. Assembly annotation indicates that the isolate has a chromosomal bla OXA-436
Andleeb, Saadia, Burnham, Carey-Ann D, D-Souza, Alaric W, Dantas, Gautam, Gul, Danish, Kwon, Jennie H, Patel, Sanket, Potter, Robert F, Shupe, Angela, Wallace, Meghan A   +9 more
core   +2 more sources

Spectroscopic and Mechanistic Studies of Heterodimetallic Forms of Metallo-β-lactamase NDM-1 [PDF]

, 2014
In an effort to characterize the roles of each metal ion in metallo-β-lactamase NDM-1, heterodimetallic analogues (CoCo-, ZnCo-, and CoCd-) of the enzyme were generated and characterized. UV–vis, 1H NMR, EPR, and EXAFS spectroscopies were used to confirm
Alyssa Hetrick, Ambler R. P., Amy R. Marts, Ankudinov A. L., Badarau A., Banci L., Bebrone C., Bennett B., Bertini I., Bertini I., Bertini I., Bertini I., Bicknell R., Bienvenue D. L., Bonomo R. A., Breece R. M., Brian Bennett, Carfi A., Copick A. J., Cricco J. A., Crisp J., Crowder M. W., Crowder M. W., David L. Tierney, Dennison C., Dennison C., deSeny D., Docobo-Perez F., Docquier J. D., Doi Y., Donaire A., Donaire A., Drawz S. M., Fernandez C. O., Fisher J. F., Garcia-Saez I., Garmer D. R., Garrity J. D., Garrity J. D., González J. M., Griffin D. H., Hao Yang, Hawk M. J., Hernandez V., Hu Z., Huang C. C., Huntington K. M., Kim Y., King D., Koh T. H., Kumarasamy K. K., Li T., Lisa M. N., Livermore D. M., Llarrull L. I., Llarrull L. I., Mahesh Aitha, McManus-Munoz S., Michael W. Crowder, Momb J., Orellano E. G., Papp-Wallace K. M., Park H., Periyannan G., Piccioli M., Prescott J. M., Reid T. S., Renault J. P., Riley E. A., Saini A., Salgado J., Sharma N., Sharma N. P., Spencer J., Stamper C., Strynadka N. C. J., Thakur P. K., Thomas P. W., Thomas P. W., Tioni M. F., Toney J. H., Ullah J. H., Vila A. J., Vila A. J., Wang Z., Wang Z., Worthington R. J., Xu D., Yamaguchi Y., Yang H., Yong D., Yuan Q., Zhang H., Zheng B., Zhu K.   +94 more
core   +3 more sources

NDM Metallo-β-Lactamases and Their Bacterial Producers in Health Care Settings

Clinical Microbiology Reviews, 2019
New Delhi metallo-β-lactamase (NDM) is a metallo-β-lactamase able to hydrolyze almost all β-lactams. Twenty-four NDM variants have been identified in >60 species of 11 bacterial families, and several variants have enhanced carbapenemase activity. SUMMARY
Wenjing Wu, Yu Feng, G. Tang, F. Qiao, A. McNally, Z. Zong   +5 more
semanticscholar   +1 more source

Detection of NDM-1/5 and OXA-48 co-producing XDR hyper-virulent Klebsiella pneumoniae in Northern Italy.

Journal of Global Antimicrobial Resistance, 2022
OBJECTIVES Using a hybrid long reads sequencing approach, we aimed to fully characterize four hypervirulent extensively drug resistant (XDR) isolates of Klebsiella pneumoniae, one of which represented the first strain isolated in Italy co-expressing NDM ...
G. Lorenzin, Floriana Gona, S. Battaglia, A. Spitaleri, F. Saluzzo, A. Trovato, F. di Marco, P. Cichero, A. Biancardi, P. Nizzero, Barbara Castiglione, P. Scarpellini, M. Moro, D. Cirillo   +13 more
semanticscholar   +1 more source

Polyclonal Dissemination of NDM-1- and NDM-9-Producing Escherichia coli and Klebsiella pneumoniae in French Polynesia [PDF]

Antimicrobial Agents and Chemotherapy, 2021
The whole-genome sequencing analysis revealed a polyclonal dissemination of NDM-1 and NDM-9 variants in Escherichia coli ( n  = 20) and Klebsiella pneumoniae ( n  = 2) in Tahiti since 2015 via interspecies transfer of three different
Saoussen Oueslati, Cécile Emeraud, Victor Grosperrin, Marc Levy, Garance Cotellon, Elodie Creton, Lauraine Gauthier, Rémy A. Bonnin, Thierry Naas, Laurent Dortet   +9 more
openaire   +2 more sources

The reaction mechanism of metallo-beta-lactamases is tuned by the conformation of an active site mobile loop [PDF]

, 2018
Carbapenems are "last resort" β-lactam antibiotics used to treat serious and life-threatening health care-associated infections caused by multidrug-resistant Gram-negative bacteria.
Alzari, Pedro M., Bethel, Christopher R., Bonomo, Robert A., Giannini, Estefanía, Klinke, Sebastian, Llarrull, Leticia Irene, Mojica, María F., Otero, Lisandro Horacio, Palacios, Antonela Rocio, Taracila, Magdalena A., Vila, Alejandro Jose   +10 more
core   +1 more source

First Outbreak of NDM-1-Producing Klebsiella pneumoniae ST11 in a Portuguese Hospital Centre during the COVID-19 Pandemic

Microorganisms, 2022
New Delhi metallo-β-lactamase (NDM) carbapenemase has been considered a global threat due to its worldwide widespread in recent years. In Portugal, a very low number of infections with NDM-producing Enterobacterales has been reported.
G. Mendes, João F. Ramalho, A. Duarte, A. Pedrosa, Ana Cristina Santana Silva, Lucía Méndez, C. Caneiras   +6 more
semanticscholar   +1 more source

Molecular and computational approaches to understand resistance of New Delhi metallo β-lactamase variants (NDM-1, NDM-4, NDM-5, NDM-6, NDM-7)-producing strains against carbapenems

Journal of Biomolecular Structure and Dynamics, 2018
The discovery of NDM-1 and its variants has caused the emergence of antibiotic resistance in the community and hospital setting, causing major concern for health care across the globe. New Delhi Metallo-β-lactamase is known to hydrolyse almost all β-lactam antibiotics.
Abid Ali, Divya Gupta, Gaurava Srivastava, Ashok sharma, Asad U. Khan   +4 more
openaire   +2 more sources