Results 1 to 10 of about 13,937 (231)

Kidney triglyceride accumulation in the fasted mouse is dependent upon serum free fatty acids[S] [PDF]

Journal of Lipid Research, 2017
Lipid accumulation is a pathological feature of every type of kidney injury. Despite this striking histological feature, physiological accumulation of lipids in the kidney is poorly understood.
Diego Scerbo, Ni-Huiping Son, Alaa Sirwi, Lixia Zeng, Kelli M. Sas, Vincenza Cifarelli, Gabriele Schoiswohl, Lesley-Ann Huggins, Namrata Gumaste, Yunying Hu, Subramaniam Pennathur, Nada A. Abumrad, Erin E. Kershaw, M. Mahmood Hussain, Katalin Susztak, Ira J. Goldberg   +15 more
doaj   +3 more sources

NEFAs Influence the Inflammatory and Insulin Signaling Pathways Through TLR4 in Primary Calf Hepatocytes in vitro

Frontiers in Veterinary Science, 2021
Transition dairy cows are often in a state of negative energy balance because of decreased dry matter intake and increased energy requirements, initiating lipid mobilization and leading to high serum β-hydroxybutyrate (BHBA) and non-esterified fatty acid
Guo-wen Liu
exaly   +3 more sources

The introduction of sexually active bucks at different moments of the oestrous cycle does not modify the NEFAs or the IGF-1 concentrations

Italian Journal of Animal Science, 2021
Non-esterified fatty acids (NEFAs) and Insulin-like growth factor-I (IGF-1) concentrations are modified after the induction of a "male effect". The present study examined the effect of the introduction of males into a group of females that were ...
L Zarazaga, José Luis Guzmán
exaly   +2 more sources

Free Fatty Acids and Endotoxins Synergically Induce Pyroptosis in Bovine Hepatocytes [PDF]

Metabolites
Background/Objectives: Elevated circulating non-esterified fatty acids (NEFAs) are closely associated with hepatic inflammatory injury in dairy cattle, simultaneously with the entry of lipopolysaccharide (LPS) into the liver.
Dan Li, Yuan Tian, Lei Tian, Hang Yu, Le Zhang, Song Wang, Changsheng Lei, Pin Long, Tao Peng, Lei Liu, Yingfang Zhou   +10 more
doaj   +2 more sources

Hand-Washing at Critical Times and Associated Factors Among Mothers/Caregivers of Under-Five Year Children in Nefas Silk Lafto Sub-City, Addis Ababa, Ethiopia

Health Services Research and Managerial Epidemiology, 2023
Background Hand washing is the simplest, most affordable, and most effective means of limiting the spread of infections. Despite increasing efforts to improve hand washing at critical times (after defecation, after handling child/adult feces or cleaning ...
Ermias Wabeto Wana
exaly   +2 more sources

Validation of the Measurement of Beta-Hydroxybutyrate and Non-Esterified Fatty Acids in Bovine Saliva: A Pilot Report [PDF]

Life
Serum beta-hydroxybutyrate (BHB) and non-esterified fatty acids (NEFAs) are biomarkers of situations of negative energetic balance in bovine. However, knowledge about their possible measurement and use in saliva is limited.
Camila P. Rubio, Lucas Rigueira, Marta Miranda, Pedro Javier Vallejo, Jesús Semitiel, David del Olmo, María D. Contreras-Aguilar, Flávio G. Silva, Elsa Lamy, Christian De la Fe, José J. Cerón, Fernando Tecles   +11 more
doaj   +2 more sources

Exploring the toxicological mechanisms of reduced fertility in dairy cows due to nonesterified fatty acids on the basis of network toxicology, transcriptomics and molecular docking [PDF]

BMC Genomics
High concentrations of nonesterified fatty acids (NEFAs) are normal metabolites of high-producing dairy cows in a state of negative energy balance (NEB), but they are thought to be strongly associated with reproductive disorders in dairy cows, which may ...
Junkai Wang, Wenjing Wang, Xiaoqi Kang, Yaqian Liang, Lulu Li, Yuqing Liu, Haihong Hao   +6 more
doaj   +2 more sources

Relationships Among In-Line Milk Fat-to-Protein Ratio, Metabolic Profile, and Inflammatory Biomarkers During Early Stage of Lactation in Dairy Cows [PDF]

Veterinary Sciences
The early lactation phase in dairy cows is characterised by significant metabolic and inflammatory changes. This study aimed to evaluate the relationship between serum nonesterified fatty acids (NEFAs), a marker of negative energy balance (NEB), and ...
Karina Džermeikaitė, Justina Krištolaitytė, Neringa Sutkevičienė, Toma Vilkonienė, Gintarė Vaičiulienė, Audronė Rekešiūtė, Akvilė Girdauskaitė, Samanta Arlauskaitė, Árpád Csaba Bajcsy, Ramūnas Antanaitis   +9 more
doaj   +2 more sources

Correlation of non-esterified fatty acids with acute coronary syndrome risk in young Chinese adults [PDF]

Frontiers in Endocrinology
ObjectiveCirculating non-esterified fatty acids (NEFAs) are linked to endothelial dysfunction and coronary artery disease (CAD) mainly in older adults.
Jian-di Wu, Jian-jing Luo, Jian-jing Luo, Jia-huan Li, Sha-li Hao, Wen-li Wang, Wu Li, Wei-wen Li, Guo-lin Huang, Guo-quan Liang, Wei-xing Wen, Wei-min He, Yang-guang Liu, Yang-xin Chen, Xiao-mei Zhang, Zao-peng He, Yuli Huang, Yuli Huang   +17 more
doaj   +2 more sources

Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT

Molecular Metabolism, 2020
Objectives: Long-chain fatty acids (LCFAs) released from adipocytes inhibit lipolysis through an unclear mechanism. We hypothesized that the LCFA receptor, FFAR4 (GPR120), which is highly expressed in adipocytes, may be involved in this feedback ...
Anna Sofie Husted, Jeppe Hvidtfeldt Ekberg, Emma Tripp   +2 more
exaly   +3 more sources