Results 21 to 30 of about 4,852 (215)

High plasma concentration of non-esterified polyunsaturated fatty acids is a specific feature of severe COVID-19 pneumonia

Scientific Reports, 2021
COVID-19 pneumonia has specific features and outcomes that suggests a unique immunopathogenesis. Severe forms of COVID-19 appear to be more frequent in obese patients, but an association with metabolic disorders is not established.
Maxime Nguyen, Abderrahmane Bourredjem, Lionel Piroth, Bélaïd Bouhemad, Antoine Jalil, Gaetan Pallot, Naig Le Guern, Charles Thomas, Thomas Pilot, Victoria Bergas, Hélène Choubley, Jean-Pierre Quenot, Pierre-Emmanuel Charles, Laurent Lagrost, Valerie Deckert, Jean-Paul Pais de Barros, Pierre-Grégoire Guinot, David Masson, Christine Binquet, Thomas Gautier, Mathieu Blot, Lymphonie study group   +21 more
doaj   +1 more source

Non-esterified fatty acids and telomere length in older adults: The Cardiovascular Health Study

Metabolism Open, 2020
Background: Telomeres shorten as organisms age, placing limits on cell proliferation and serving as a marker of biological aging. Non-esterified fatty acids (NEFAs) are a key mediator of age-related metabolic abnormalities. We aimed to determine if NEFAs
Peter Ahiawodzi, Annette L. Fitzpatrick, Luc Djousse, Joachim H. Ix, Jorge R. Kizer, Kenneth J. Mukamal   +5 more
doaj   +1 more source

Lietuvos šaulių sąjungos ryšiai su išeivija JAV: Antano Žmuidzinavičiaus atvejis | Relations between the Lithuanian Riflemen’s Union and the Lithuanian Diaspora in the USA: The Case of Antanas Žmuidzinavičius

Acta Historica Universitatis Klaipedensis, 2014
The paper analyses the relations between the Lithuanian Riflemen’s Union (LRU) and the diaspora in the USA, established at the very beginning of the LRU’s activity.
Mindaugas Nefas
doaj   +1 more source

Systemic redox status in lung cancer patients is related to altered glucose metabolism. [PDF]

PLoS ONE, 2018
Altered systemic redox status is often observed in lung cancer. However, detailed information on factors other, than smoking, which influence this perturbation is rather scarce.
Katarzyna Zabłocka-Słowińska, Sylwia Płaczkowska, Anna Prescha, Konrad Pawełczyk, Monika Kosacka, Irena Porębska, Halina Grajeta   +6 more
doaj   +1 more source

Serum Nonesterified Fatty Acids and Incident Stroke: The CHS

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Significant associations between total nonesterified fatty acid (NEFA) concentrations and incident stroke have been reported in some prospective cohort studies.
Neil K. Huang, Mary L. Biggs, Nirupa R. Matthan, Luc Djoussé, W. T. Longstreth, Kenneth J. Mukamal, David S. Siscovick, Alice H. Lichtenstein   +7 more
doaj   +1 more source

Increased NEFA levels reduce blood Mg2+ in hypertriacylglycerolaemic states via direct binding of NEFA to Mg2+ [PDF]

Diabetologia, 2018
The blood triacylglycerol level is one of the main determinants of blood Mg2+ concentration in individuals with type 2 diabetes. Hypomagnesaemia (blood Mg2+ concentration 27 kg/m2) who participated in the 300-Obesity study (an observational cross-sectional cohort study, as part of the Human Functional Genetics Projects), we investigated the association
Kurstjens, S, de Baaij, JHF, Overmars-Bos, C, Van Den Munckhof, ICL, Garzero, V, De Vries, MA, Burggraaf, B, Van Diepen, JA, Riksen, NP, Rutten, JHW, Netea, MG, Cabezas, M, Bindels, RJM, Ashcroft, FM, Tack, CJJ, Hoenderop, JGJ   +15 more
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Serum nonesterified fatty acids have utility as dietary biomarkers of fat intake from fish, fish oil, and dairy in women[S]

Journal of Lipid Research, 2020
Nutritional studies rely on various biological specimens for FA determination, yet it is unclear how levels of serum NEFAs correlate with other circulating lipid pools. Here, we used a high-throughput method (
Sandi M. Azab, Russell J. de Souza, Koon K. Teo, Sonia S. Anand, Natalie C. Williams, Jordan Holzschuher, Chris McGlory, Stuart M. Philips, Philip Britz-McKibbin   +8 more
doaj   +1 more source

Physiological regulation of NEFA availability: lipolysis pathway [PDF]

Proceedings of the Nutrition Society, 2004
Plasma NEFA are an important energy substrate and, furthermore, play a key role in the induction of insulin resistance in the body. The availability of NEFA is determined predominantly by their mobilization from adipose tissue triacylglycerol stores by the process of lipolysis.
V, Stich, M, Berlan
openaire   +2 more sources

Changes in plasma free fatty acids in obese patients before and after bariatric surgery highlight alterations in lipid metabolism

Scientific Reports, 2022
Obesity is a complex disease that increases an individual’s risk of developing other diseases and health-related problems. A common feature is dyslipidemia characterized by increased levels of plasma lipids, which include non-esterified fatty acids ...
Stephen J. Hierons, Kazim Abbas, Amélie I. S. Sobczak, Michela Cerone, Terry K. Smith, Ramzi A. Ajjan, Alan J. Stewart   +6 more
doaj   +1 more source

An Integrated Multi-OMICS Approach Highlights Elevated Non-Esterified Fatty Acids Impact BeWo Trophoblast Metabolism and Lipid Processing

Metabolites, 2023
Maternal obesity and gestational diabetes mellitus (GDM) are linked with impaired placental function and early onset of non-communicable cardiometabolic diseases in offspring. Previous studies have highlighted that the dietary non-esterified fatty acids (
Zachary J. W. Easton, Ousseynou Sarr, Lin Zhao, Adriana Zardini Buzatto, Xian Luo, Shuang Zhao, Liang Li, Timothy R. H. Regnault   +7 more
doaj   +1 more source