Results 21 to 30 of about 3,674 (185)

Systemic redox status in lung cancer patients is related to altered glucose metabolism. [PDF]

open access: yesPLoS ONE, 2018
Altered systemic redox status is often observed in lung cancer. However, detailed information on factors other, than smoking, which influence this perturbation is rather scarce.
Katarzyna Zabłocka-Słowińska   +6 more
doaj   +1 more source

Speaking the Unspeakable: Engaging Nefas in Lucan and Rwanda 1994

open access: yesthersites. Journal for Transcultural Presences & Diachronic Identities from Antiquity to Date, 2017
Lucan’s Bellum Civile can be read as an epic that functions in the mode of trauma literature, i.e. a work that explicitly seeks to represent a horror that defies its very representation.
Mark Allen Thorne
doaj   +1 more source

Serum Nonesterified Fatty Acids and Incident Stroke: The CHS

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Significant associations between total nonesterified fatty acid (NEFA) concentrations and incident stroke have been reported in some prospective cohort studies.
Neil K. Huang   +7 more
doaj   +1 more source

Increased NEFA levels reduce blood Mg2+ in hypertriacylglycerolaemic states via direct binding of NEFA to Mg2+ [PDF]

open access: yesDiabetologia, 2018
The blood triacylglycerol level is one of the main determinants of blood Mg2+ concentration in individuals with type 2 diabetes. Hypomagnesaemia (blood Mg2+ concentration 27 kg/m2) who participated in the 300-Obesity study (an observational cross-sectional cohort study, as part of the Human Functional Genetics Projects), we investigated the association
Kurstjens, S   +15 more
openaire   +4 more sources

Serum nonesterified fatty acids have utility as dietary biomarkers of fat intake from fish, fish oil, and dairy in women[S]

open access: yesJournal of Lipid Research, 2020
Nutritional studies rely on various biological specimens for FA determination, yet it is unclear how levels of serum NEFAs correlate with other circulating lipid pools. Here, we used a high-throughput method (
Sandi M. Azab   +8 more
doaj   +1 more source

Physiological regulation of NEFA availability: lipolysis pathway [PDF]

open access: yesProceedings of the Nutrition Society, 2004
Plasma NEFA are an important energy substrate and, furthermore, play a key role in the induction of insulin resistance in the body. The availability of NEFA is determined predominantly by their mobilization from adipose tissue triacylglycerol stores by the process of lipolysis.
V, Stich, M, Berlan
openaire   +2 more sources

Are we waking up to the effects of NEFA? [PDF]

open access: yesDiabetologia, 2015
NEFA are mobilised from adipose tissues during fasting or stress. Under conditions of acute or chronic NEFA excess, skeletal muscle and hepatic insulin resistance may ensue. Hence, a wealth of literature has focused on the crosstalk between NEFA and glucose in the pathogenesis of insulin resistance.
Jonathan C, Jun, Vsevolod Y, Polotsky
openaire   +2 more sources

NFκB/Orai1 Facilitates Endoplasmic Reticulum Stress by Oxidative Stress in the Pathogenesis of Non-alcoholic Fatty Liver Disease

open access: yesFrontiers in Cell and Developmental Biology, 2019
Non-esterified fatty acids (NEFAs) promote de novo lipogenesis, which caused abnormal hepatic lipid accumulation, by the NFκB–Orai1 pathway. Oxidative stress and endoplasmic reticulum (ER) stress have been recognized as key mechanisms in non-alcoholic ...
Bingbing Zhang   +8 more
doaj   +1 more source

Changes in plasma free fatty acids in obese patients before and after bariatric surgery highlight alterations in lipid metabolism

open access: yesScientific Reports, 2022
Obesity is a complex disease that increases an individual’s risk of developing other diseases and health-related problems. A common feature is dyslipidemia characterized by increased levels of plasma lipids, which include non-esterified fatty acids ...
Stephen J. Hierons   +6 more
doaj   +1 more source

An Integrated Multi-OMICS Approach Highlights Elevated Non-Esterified Fatty Acids Impact BeWo Trophoblast Metabolism and Lipid Processing

open access: yesMetabolites, 2023
Maternal obesity and gestational diabetes mellitus (GDM) are linked with impaired placental function and early onset of non-communicable cardiometabolic diseases in offspring. Previous studies have highlighted that the dietary non-esterified fatty acids (
Zachary J. W. Easton   +7 more
doaj   +1 more source

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