Results 11 to 20 of about 13,937 (231)

Prospective observational study and mechanistic evidence showing lipolysis of circulating triglycerides worsens hypertriglyceridemic acute pancreatitis [PDF]

The Journal of Clinical Investigation
BACKGROUND While most hypertriglyceridemia is asymptomatic, hypertriglyceridemia-associated acute pancreatitis (HTG-AP) can be more severe than AP of other etiologies. The reasons underlying this are unclear. We thus examined whether lipolytic generation
Prasad Rajalingamgari, Biswajit Khatua, Megan J. Summers, Sergiy Kostenko, Yu-Hui H. Chang, Mohamed Elmallahy, Arti Anand, Anoop Narayana Pillai, Mahmoud Morsy, Shubham Trivedi, Bryce McFayden, Sarah Jahangir, Christine L.H. Snozek, Vijay P. Singh   +13 more
doaj   +2 more sources

Dynamic Adaptation of Hematological Parameters, Albumin, and Non-Esterified Fatty Acids in Saddlebred and Standardbred Horses During Exercise [PDF]

Animals
The response to exercise following a rest period may vary among horse breeds based on the importance of the hematological and hematochemical profiles of athletic horses.
Giuseppe Piccione, Francesca Arfuso, Elisabetta Giudice, Francesca Aragona, Pietro Pugliatti, Maria Francesca Panzera, Alessandro Zumbo, Vincenzo Monteverde, Vincenzo Bartolo, Adalberto Barbera, Claudia Giannetto   +10 more
doaj   +2 more sources

Resveratrol Alleviates NEFA-Induced Oxidative Damage in Bovine Mammary Epithelial Cells by Restoring Mitochondrial Function [PDF]

Animals
In periparturient dairy cows, high non-esterified fatty acids (NEFAs) caused by a severe negative energy balance induce oxidative stress and metabolic dysfunction, which pose a severe challenge to the dairy industry.
Longwei Sun, Junpeng Huang, Xiangyang Dou, Zhenyu Dong, Yuan Li, Shujing Tan, Ran Yu, Chengmin Li, Weiguo Zhao   +8 more
doaj   +2 more sources

Postpartum energy balance in water buffaloes: implications on health and reproduction [PDF]

SPERMOVA, 2020
In this article, it was reviewed as the postpartum negative energy balance (NEB) affects the health and the reproductive efficiency of water buffaloes. The increase in the world buffalo population has been accompanied by an improvement in the milk yield ...
Adriana Morgado-Osorio, Hector Nava-Trujillo, Robert Valeris-Chacin, Simón Zambrano-Salas, Armando Quintero-Moreno   +4 more
doaj   +1 more source

Associations between peripartum lying and activity behaviour and blood non-esterified fatty acids and β-hydroxybutyrate in grazing dairy cows

Animal, 2022
During early lactation, most dairy cows experience negative energy balance (NEB). Failure to cope with this NEB, however, can place cows at greater risk of developing metabolic disease.
S.J. Hendriks, C.V.C. Phyn, S-A. Turner, K.R. Mueller, B. Kuhn-Sherlock, D.J. Donaghy, J.M. Huzzey, J.R. Roche   +7 more
doaj   +1 more source

Cocultured porcine granulosa cells respond to excess non-esterified fatty acids during in vitro maturation

Journal of Ovarian Research, 2021
Background Non-esterified fatty acids (NEFAs) are one of the main lipid components of follicular fluid at concentrations that depend on circulating levels.
Meihong Shi, Marc-André Sirard
doaj   +1 more source

High plasma concentration of non-esterified polyunsaturated fatty acids is a specific feature of severe COVID-19 pneumonia

Scientific Reports, 2021
COVID-19 pneumonia has specific features and outcomes that suggests a unique immunopathogenesis. Severe forms of COVID-19 appear to be more frequent in obese patients, but an association with metabolic disorders is not established.
Maxime Nguyen, Abderrahmane Bourredjem, Lionel Piroth, Bélaïd Bouhemad, Antoine Jalil, Gaetan Pallot, Naig Le Guern, Charles Thomas, Thomas Pilot, Victoria Bergas, Hélène Choubley, Jean-Pierre Quenot, Pierre-Emmanuel Charles, Laurent Lagrost, Valerie Deckert, Jean-Paul Pais de Barros, Pierre-Grégoire Guinot, David Masson, Christine Binquet, Thomas Gautier, Mathieu Blot, Lymphonie study group   +21 more
doaj   +1 more source

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez   +22 more
wiley   +1 more source

Increased NEFA levels reduce blood Mg2+ in hypertriacylglycerolaemic states via direct binding of NEFA to Mg2+ [PDF]

Diabetologia, 2018
The blood triacylglycerol level is one of the main determinants of blood Mg2+ concentration in individuals with type 2 diabetes. Hypomagnesaemia (blood Mg2+ concentration 27 kg/m2) who participated in the 300-Obesity study (an observational cross-sectional cohort study, as part of the Human Functional Genetics Projects), we investigated the association
Kurstjens, S, de Baaij, JHF, Overmars-Bos, C, Van Den Munckhof, ICL, Garzero, V, De Vries, MA, Burggraaf, B, Van Diepen, JA, Riksen, NP, Rutten, JHW, Netea, MG, Cabezas, M, Bindels, RJM, Ashcroft, FM, Tack, CJJ, Hoenderop, JGJ   +15 more
openaire   +4 more sources

Non-esterified fatty acids and telomere length in older adults: The Cardiovascular Health Study

Metabolism Open, 2020
Background: Telomeres shorten as organisms age, placing limits on cell proliferation and serving as a marker of biological aging. Non-esterified fatty acids (NEFAs) are a key mediator of age-related metabolic abnormalities. We aimed to determine if NEFAs
Peter Ahiawodzi, Annette L. Fitzpatrick, Luc Djousse, Joachim H. Ix, Jorge R. Kizer, Kenneth J. Mukamal   +5 more
doaj   +1 more source