Results 81 to 90 of about 8,883 (209)
PLoS ONE, 2009 Glomerular visceral epithelial cells (podocytes) contain interdigitated processes that form specialized intercellular junctions, termed slit diaphragms, which provide a selective filtration barrier in the renal glomerulus.
Tomonori Hirose +9 more
doaj +1 more source
Expression of human nephrin mRNA in diabetic nephropathy [PDF]
Nephrology Dialysis Transplantation, 2004 Diabetic nephropathy (DN) is associated with functional changes in the filtration barrier, and microalbuminuria is a strong predictor of the development of overt DN. Nephrin is a novel podocyte-specific protein which localizes at the slit diaphragm.
Masao, Toyoda +7 more
openaire +2 more sources
Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.This systematic review compiles and analyses 364 studies on chronic kidney disease (CKD) that investigated extracellular vesicles (EVs) for diagnostic and therapeutic applications. By systematically categorizing data according to EV source and cargo, it provides an integrated overview of EV application for CKD, highlighting common approaches and shared
Tunahan Ergunay +2 more
wiley +1 more source
, 2005 Kidneys, the main excretory organs in vertebrates, play central role in removing water soluble metabolic waste products from the organism. Many acquired and inherited renal diseases in man lead to kidney dysfunction and nephrotic syndrome - life ...
Olga Beltcheva (19523938)
core
Is There a Diagnostic and Prognostic Role for Anti-Nephrin Autoantibodies in Diabetic Nephropathy?
AntibodiesDiabetic nephropathy (DN) is one of the key causes of end-stage kidney disease worldwide, especially in developed countries. The classic pathogenic development of DN is characterized by microalbuminuria which would progress to nephrotic-range proteinuria
Han Sean Lee +4 more
doaj +1 more source
Family pedigree, mutation analysis and nephrin immunostaining.
, 2018 (A) Pedigree depicting the proband (P, solid arrow) as a compound heterozygote for inherited A419T and C623F mutations in NPHS1. The parents are obligate carriers of each mutation, and the sibling is mutation negative.
Claire E. Martin (5746709) +5 more
core +1 more source
DiagnosticsObjectives: To compare the levels of podocyte damage markers nephrin and podocalyxin in urine samples taken at the time of gestational diabetes mellitus (GDM) diagnosis and at birth.
Fatma Tanilir Cagiran +3 more
doaj +1 more source
Advanced NanoBiomed Research, Volume 6, Issue 4, April 2026.This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
Nephrin expression in human epidermal keratinocytes and its implication in poor wound closure
, 2022 Nephrin is a type-1 transmembrane protein and a component of the slit diaphragm renal-filtration barrier. It has several functions in actin remodeling and cell-cell adhesion.
임범진, 오상호, 김도영
core +1 more source
Biological Research, 2009 We present the analysis of an intronic polymorphism of the nephrin gene and its relationship to the development of diabetic nephropathy in a study of diabetes type 1 and type 2 patients.
RODRIGO GONZÁLEZ +8 more
doaj