Results 61 to 70 of about 1,206 (172)
Life history and ecological genetics of the colonial ascidian Botryllus schlosseri [PDF]
, 2015 The colonial ascidian Botryllus schlosseri is a cosmopolitan, marine filter feeder, introduced as a laboratory research organism in the 1950s. Currently, it is widely used in many laboratories to investigate a variety of biological questions.
Ballarin, Loriano +7 more
core +1 more source
Comprehensive functional analysis of Rab GTPases in Drosophila nephrocytes [PDF]
Cell and Tissue Research, 2017 The Drosophila nephrocyte is a critical component of the fly renal system and bears structural and functional homology to podocytes and proximal tubule cells of the mammalian kidney. Investigations of nephrocyte cell biological processes are fundamental to understanding the insect renal system.
Yulong, Fu +5 more
openaire +2 more sources
Cubilin and Amnionless Mediate Protein Reabsorption in Drosophila Nephrocytes [PDF]
Journal of the American Society of Nephrology, 2013 The insect nephrocyte and the mammalian glomerular podocyte are similar with regard to filtration, but it remains unclear whether there is an organ or cell type in flies that reabsorbs proteins. Here, we show that the Drosophila nephrocyte has molecular, structural, and functional similarities to the renal proximal tubule cell.
Fujian, Zhang +4 more
openaire +2 more sources
Disease Models & Mechanisms, 2020 Drosophila nephrocytes share functional, structural and molecular similarities with human podocytes. It is known that podocytes express the rabphilin 3A (RPH3A)-RAB3A complex, and its expression is altered in mouse and human proteinuric disease ...
Estela Selma-Soriano +5 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2023 High alkalinity stress was considered as a major risk factor for aquatic animals surviving in saline-alkaline water. However, few information exists on the effects of alkalinity stress in crustacean species.
Qianqian Ge +3 more
doaj +1 more source
MTOR regulates endocytosis and nutrient transport in proximal tubular cells [PDF]
, 2016 Renal proximal tubular cells constantly recycle nutrients to ensure minimal loss of vital substrates into the urine. Although most of the transport mechanisms have been discovered at the molecular level, little is known about the factors regulating ...
Alexey A. Larionov +20 more
core +2 more sources
Loss of cytoskeletal and polarity regulation as key pathogenic principles in glomerular disease [PDF]
, 2023 Injury to glomerular podocytes constitutes the predominant cause of glomerular diseases and therefore loss of kidney function. Podocytes are specialized epithelial cells within glomeruli indispensable for the filtration process.
Odenthal, Johanna
core
Filling the Gap: Drosophila Nephrocytes as Model System in Kidney Research [PDF]
Journal of the American Society of Nephrology, 2019 New and efficient sequencing technologies are constantly identifying novel gene variants in patients that may be the genetic cause of renal diseases. Recent studies show that, even for adult patients with CKD, monogenic causes can be detected in around 10% of patients.[1][1] Novel causative ...
Zvonimir, Marelja, Matias, Simons
openaire +2 more sources
Біологія тварин, 2023 Principles of reptile treatment are significantly different from the drug therapy for mammals and birds, which is primarily due to anatomical and physiological peculiarities of reptiles.
R. S. Dankovych, V. I. Chuliuk
doaj +1 more source
APOL1-G1 in Nephrocytes Induces Hypertrophy and Accelerates Cell Death [PDF]
Journal of the American Society of Nephrology, 2016 People of African ancestry carrying certain APOL1 mutant alleles are at elevated risk of developing renal diseases. However, the mechanisms underlying APOL1-associated renal diseases are unknown. Because the APOL1 gene is unique to humans and some primates, new animal models are needed to understand the function of APOL1 in vivo.
Yulong, Fu +8 more
openaire +2 more sources