Results 61 to 70 of about 422 (124)

Antioxidant, Antiinflammatory and Antiapoptotic Effects of Lycopene in Rats With Vancomycin‐Induced Nephrotoxicity

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 2, August 2025.
Vancomycin caused nephrotoxicity in rats. Lycopene treatment showed ameliorative efficacy on vancomycin‐induced nephrotoxicity. This efficacy of lycopene was dose dependent. ABSTRACT Background The most important side effect of vancomycin (Vanco) is nephrotoxicity (NPT).
Hülya Demirkapı Atik, Orkun Atik, Recep Aslan, Yavuz Osman Birdane, Abdullah Eryavuz   +4 more
wiley   +1 more source

Evolved and Plastic Gene Expression in Adaptation of a Specialist Fly to a Novel Niche

Molecular Ecology, Volume 34, Issue 4, February 2025.
ABSTRACT How gene expression evolves to enable divergent ecological adaptation and how changes in gene expression relate to genomic architecture are pressing questions for understanding the mechanisms enabling adaptation and ecological speciation. Furthermore, how plasticity in gene expression can both contribute to and be affected by the process of ...
Rachel A. Steward, Jesús Ortega Giménez, Shruti Choudhary, Oliver Moss, Yi Su, Olivier Van Aken, Anna Runemark   +6 more
wiley   +1 more source

Origin and evolution of microvilli

Biology of the Cell, Volume 116, Issue 11, November 2024.
Microvilli are widespread organelles of animal cells that frequently play a role in sensation and feeding. Ansel et al. reconstitute their origin and evolution by performing a broad morphological survey of microvilli in animals and their unicellular relatives, coupled with a bioinformatic study of the phylogenetic distribution of the main microvillar ...
Mylan Ansel, Kaustubh Ramachandran, Gautam Dey, Thibaut Brunet   +3 more
wiley   +1 more source

Sequence analysis, homology modeling, tissue expression, and potential functions of seven putative acetylcholinesterases in the spider Cupiennius salei

European Journal of Neuroscience, Volume 60, Issue 7, Page 5785-5811, October 2024.
Analysis of the Cupiennius salei transcriptome identified seven putative Acetylcholine esterase (AChE) genes, six for soluble AChEs and one, CsAChE7, likely encoding a membrane‐bound synaptic AChE. Soluble AChEs were expressed in the central nervous system, peripheral nervous system, muscle, and heart, while CsAChE7 was exclusive to the nervous system.
Hongxia Liu, Jinwon Jang, Andrew S. French, Päivi H. Torkkeli   +3 more
wiley   +1 more source

Variation in Whole‐Body Regeneration Between Botrylloides Morphs and Species

Journal of Marine Sciences, Volume 2024, Issue 1, 2024.
Marine invertebrates exhibit an impressive regenerative capacity. Among these lineages, colonial ascidians possess the unique ability of whole‐body regeneration (WBR), in which a new adult (zooid) body is restored. Botrylloides species exemplify this regenerative capacity by regenerating new adults solely from vascular tissue within approximately 2 ...
Berivan Temiz, Megan J. Wilson, Garth L. Fletcher   +2 more
wiley   +1 more source

Transgenic human nephrin in Drosophila nephrocytes facilitates variant analysis

Kidney International
Nephrin, the key structural protein of the slit diaphragm, is encoded by NPHS1. Pathogenic variants in this gene are the primary cause of congenital nephrotic syndrome. About 400 variants have been described but functional characterization in vitro is very limited.Here, we express human nephrin in Drosophila nephrocytes, which possess a molecularly ...
Julia Melina Wolff, Konrad Lang, Mengmeng Chen, Julian Milosavljevic, Séverine Kayser, Martin Helmstädter, Gerd Walz, Ahmed Abed, Lea Gerstner, Sami Bahar, Maximilian H. Ulbrich, Tobias Hermle   +11 more
openaire   +3 more sources

EVALUATION OF SOME ANTIOXIDANTS’ EFFECTS IN KIDNEY HISTOLOGICAL STRUCTURE OF WEANED PIGS, INTOXICATED WITH DEOXYNIVALENOL (DON)

Scientific Papers Animal Science and Biotechnologies, 2023
Deoxynivalenol is a mycotoxin produced by fungi of the Fusarium genera, which are abundant in various cereal crops and processed grains. In order to protect cell structure within the tissues studied, we tried various experimental variants by ...
GABI DUMITRESCU, D. DRINCEANU, LAVINIA STEF, D. STEF, LILIANA PETCULESCU-CIOCHINA, LILIANA BOCA, C. JULEAN   +6 more
doaj  

Cilastatin protects against imipenem-induced nephrotoxicity via inhibition of renal organic anion transporters (OATs)

Acta Pharmaceutica Sinica B, 2019
Imipenem is a carbapenem antibiotic. However, Imipenem could not be marketed owing to its instability and nephrotoxicity until cilastatin, an inhibitor of renal dehydropeptidase-I (DHP-I), was developed.
Xiaokui Huo, Qiang Meng, Changyuan Wang, Yanna Zhu, Zhihao Liu, Xiaodong Ma, Xiaochi Ma, Jinyong Peng, Huijun Sun, Kexin Liu   +9 more
doaj   +1 more source

What is your diagnosis: Acute hemolysis in a Limousin bull

Veterinary Clinical Pathology, Volume 54, Issue S1, Page S54-S56, July 2025.
Alexandre Bertin, Thomas Bonnet, Matthias Lambert, Emi Ludemann, Fabien Corbière, Corine Boucraut, Marie‐Noëlle Lucas, Catherine Trumel   +7 more
wiley   +1 more source

Tau reduction impairs nephrocyte function in Drosophila

BMB Reports
Tau, a microtubule-associated protein, is known for its significant involvement in neurodegenerative diseases. While various molecular and immunohistochemical techniques have confirmed the presence of Tau in podocytes, its precise function within these cells remains elusive.
Lee, Jiyoung, Kim, Dayoung, Cha, Sun Joo, Lee, Jang-Won, Lee, Eun-Young, Kim, Hyung-Jun, Kim, Kiyoung   +6 more
openaire   +1 more source