Results 101 to 110 of about 4,454 (194)
Profiling Anti-Neu5Gc IgG in Human Sera with a Sialoglycan Microarray Assay [PDF]
Journal of Visualized Experiments, 2017 Cells are covered with a cloak of carbohydrate chains (glycans) that is commonly altered in cancer and that includes variations in sialic acid (Sia) expression. These are acidic sugars that have a 9-carbon backbone and that cap vertebrate glycans on cell surfaces.
Leviatan Ben-Arye, Shani +3 more
openaire +4 more sources
Beyond FimH: Diversity and Relevance of Carbohydrate‐Binding Fimbrial Proteins in Escherichia coli
ChemBioChem, Volume 26, Issue 17, September 15, 2025.This review discusses fimbrial lectins found in Escherichia coli (E. coli) other than FimH, which could be targeted to treat E. coli pathogenicity as an alternative to antibiotic treatment. Escherichia coli (E. coli) is responsible for multiple diseases in humans and animals.
Oliwier R. Dulawa +3 more
wiley +1 more source
Anti-Neu5Gc Antibody Kit Protocol - ELISA v4 [PDF]
, 2019 This protocol is essentially the same as a standard ELISA protocol, with one major exception - all animal compounds must be avoided in buffers, etc. because they contain Neu5Gc, which will interfere with antibody activity and result in misleading data.
openaire +1 more source
Antibodies, 2020 Human natural antibodies to mammalian carbohydrate antigens (MCA) bind to carbohydrate-antigens synthesized in other mammalian species and protect against zoonotic virus infections.
Uri Galili
doaj +1 more source
Journal of Separation Science, Volume 48, Issue 9, September 2025.ABSTRACT Ion exchange chromatography (IEC) hyphenated to mass spectrometry (MS) is a powerful non‐denaturing technique used for analyzing protein charge heterogeneity (including posttranslational modifications such as deamidation, phosphorylation, and sialylation), as well as for characterizing complex protein mixtures. This review provides an overview
Ziran Zhai +3 more
wiley +1 more source
Sialic acids in biological and therapeutic processes: opportunities and challenges [PDF]
, 2015 It is now well documented that carbohydrates play multiple roles in biological processes, and hence are interesting targets for chemical biology and medicinal chemistry programmes.
Helen MI Osborn +3 more
core +1 more source
Cell Proliferation, Volume 58, Issue 9, September 2025.Schematic representation of generation of 8‐gene‐edited cloned pigs and their verification by pig to non‐human primate kidney xenotransplantation. ABSTRACT Gene‐edited (GE) pig‐to‐human xenotransplantation continues to make breakthroughs, but which kind of gene combination is suitable for organ‐specific transplantation remains unclear.
Jiaoxiang Wang +23 more
wiley +1 more source
Molecules, 2019 The animal product hazard factor N-glycolylneuraminic (Neu5Gc) and brain nutrient substance N-acetylneuraminic acid (Neu5Ac) were studied at the M062X/6-311 + G(d,p) geometry optimization level.
Rui Chang, Bowen Yang, Qiu-Jin Zhu
doaj +1 more source
Study on the relationship between red meat, dietary Neu5Gc intake and anti-Neu5Gc antibody [PDF]
, 2015 唾液酸类化合物是以九碳糖神经氨酸(5-amino-3,5-dideoxy-D-glycero-D-galactononulsonicacid)为基本结构的一族衍生物的总称。目前，已分离和鉴定的有50余种，包括N-乙酰基神经氨酸(N-acetylneuraminicacid,Neu5Ac)、N-羟乙酰基神经氨酸(N-glycoulylneuraminicacid,Neu5Gc)和2－酮基－3－脱氧九酮糖酸(2-keto-3-deoxy-nonulosonicacid,KDN)三种核心单体 ...
范杏丹
core
Large‐Scale Chemoenzymatic Synthesis of a Glycophorin A Tetrasaccharide Motif and Its Analogues
Asian Journal of Organic Chemistry, Volume 14, Issue 8, August 2025.A large‐scale chemoenzymatic method was developed to synthesize natural and modified analogues of the Glycophorin A tetrasaccharide with either C9 or C5 terminal α‐2,3‐sialic acid variants. Selective α‐2,6‐sialylation of galactosamine was achieved by maintaining acetylation of the galactose during the course of enzymatic reactions. The products can aid
Ivan A. Gagarinov +5 more
wiley +1 more source