Results 91 to 100 of about 3,321 (184)
Perinatal Gut Dysbiosis Reduces Milk Oligosaccharides via LPS‐Mediated Gut–Mammary Signaling in Mice
Food Frontiers, Volume 7, Issue 2, March 2026.Maternal gut dysbiosis elevates Gram‐negative bacterial lipopolysaccharide (LPS), which enters circulation and accumulates in mammary tissue. This compromises the blood–milk barrier and suppresses key enzymatic genes, ultimately reducing milk oligosaccharide synthesis and potentially affecting neonatal gut microbiota through breastfeeding.
Man‐Lin Zhou +9 more
wiley +1 more source
Molecules, 2019 The animal product hazard factor N-glycolylneuraminic (Neu5Gc) and brain nutrient substance N-acetylneuraminic acid (Neu5Ac) were studied at the M062X/6-311 + G(d,p) geometry optimization level.
Rui Chang, Bowen Yang, Qiu-Jin Zhu
doaj +1 more source
PLoS ONE, 2014 The expression of N-glycolylneuraminic acid (Neu5Gc) and the cytotoxic T cell (CT) carbohydrate can impact the severity of muscular dystrophy arising from the loss of dystrophin in mdx mice.
Paul T Martin +8 more
doaj +1 more source
Distribution of anti-Neu5Gc IgG titers against a mixture of epitopes in NHS II population.
, 2018 Plasma total and inhibitable anti-Neu5Gc IgG levels were quantified by ELISA using wild-type mouse serum as a target that contains naturally occurring Neu5Gc containing sialoglycoproteins epitopes as antigens (N = 46; Table 1).
Annie N. Samraj (5410286) +15 more
core +1 more source
Antitumor and cytotoxic properties of a humanized antibody specific for the GM3(Neu5Gc) ganglioside
Immunobiology, 2015 Gangliosides are sialic acid-bearing glycosphingolipids expressed on all mammalian cell membranes, and participate in several cellular processes. During malignant transformation their expression changes, both at the quantitative and qualitative levels. Of particular interest is the overexpression by tumor cells of Neu5Gc-gangliosides, which are absent,
Dorvignit, Denise +9 more
openaire +4 more sources
Proinflammatory Mechanism of N-Glycolylneuraminic Acid in Mice through Regulating the Gut Microbiota [PDF]
Shipin KexueIn this study, the effect of 18 weeks of dietary supplementation of porcine submaxillary gland mucin (PSM) as an abundant source of N-hydroxyacetylneuraminic acid (Neu5Gc) on the expression of proteins involved in the nuclear factor kappa-B (NF-κB ...
HE Leli, LIU Chuxin, XIAO Yi, SHEN Qingwu, WU Yanyang
doaj +1 more source
Anti-Neu5Gc Antibody Kit Protocol - Flow Cytometry v1
, 2016 Anti-Neu5Gc may be used for staining cells prior to analysis by Flow Cytometry. This kit contains all the essential components needed to identify Neu5Gc on the surface of cells by flow cytometry.
Kelsey Miller
core +1 more source
DataSheet_1_Chimeric antigen receptor T cells targeting the GM3(Neu5Gc) ganglioside.docx
Chimeric antigen receptor (CAR) T cell technology has ushered in a new era of immunotherapy, enabling the targeting of a broad range of surface antigens, surpassing the limitations of traditional T cell epitopes.
Geir Åge Løset (13752502) +6 more
core +1 more source
Anti-Neu5Gc Antibody Kit Protocol - ELISA v3 [PDF]
, 2018 This protocol is essentially the same as a standard ELISA protocol, with one major exception - all animal compounds must be avoided in buffers, etc. because they contain Neu5Gc, which will interfere with antibody activity and result in misleading data.
openaire +1 more source
Distribution of Anti-Neu5Gc IgG titers in EPIC-Norfolk cohort using defined ELISA target antigens.
, 2018 Each dot represents a value for a single subject. (A) Levels of serum anti-Neu5Gc IgG quantified by ELISA using Neu5Gcα2-polyacrylamide (Neu5Gcα2-PAA) as the target antigen (N = 2716). The mean anti-Neu5Gc IgG titer was 8.6 μg/ml (SD±10.6). (B) Levels of
Annie N. Samraj (5410286) +15 more
core +1 more source