Results 71 to 80 of about 3,321 (184)

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

open access: yesMass Spectrometry Reviews, Volume 45, Issue 4, Page 829-850, July/August 2026.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song   +3 more
wiley   +1 more source

Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming

open access: yesPlant Biotechnology Journal, Volume 24, Issue 7, Page 4619-4639, July 2026.
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska   +2 more
wiley   +1 more source

A simple method to detect overall human anti-Neu5Gc reactivity.

open access: yes, 2013
A. Human antibodies can bind to mouse glycoproteins from WT (Neu5Gc-positive) or Cmah-KO (Neu5Gc-deficient) mice revealing anti-Neu5Gc and/or general anti-mouse reactivity. B.
Hai Yu (366836)   +5 more
core   +1 more source

An In Silico Functional Analysis of Non-Synonymous Single-Nucleotide Polymorphisms of Bovine CMAH Gene and Potential Implication in Pathogenesis

open access: yesPathogens, 2023
The sugar molecule N-glycolylneuraminic acid (Neu5Gc) is one of the most common sialic acids discovered in mammals. Cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) catalyses the conversion of N-acetylneuraminic acid (Neu5Ac) to Neu5Gc ...
Oluwamayowa Joshua Ogun   +3 more
doaj   +1 more source

Global Consultation for Clinical Xenotransplantation: International Xenotransplantation Association Consensus and Communiqué Update

open access: yesXenotransplantation, Volume 33, Issue 4, July/August 2026.
ABSTRACT Xenotransplantation has entered a phase of accelerated clinical translation, necessitating renewed international consensus on governance, ethics, safety, and regulatory oversight. In September 2025, the International Xenotransplantation Association (IXA), in partnership with The Transplantation Society (TTS) and with engagement from the World ...
Wayne J. Hawthorne   +25 more
wiley   +1 more source

Investigation of Neu5Gc Tumour Antigens in Pancreatic Cancer

open access: yes, 2022
Background:Pancreatic cancer is the most lethal common cancer and fifth leading cause of cancer mortality in Australia. The prognosis for those diagnosed is extremely poor, with only 2 – 9% of patients surviving five years after diagnosis.
De Bisscop, Xavier
core   +1 more source

Gene expression and pathway analysis of effects of the CMAH deactivation on mouse lung, kidney and heart. [PDF]

open access: yesPLoS ONE, 2014
N-glycolylneuraminic acid (Neu5Gc) is generated by hydroxylation of CMP-Neu5Ac to CMP-Neu5Gc, catalyzed by CMP-Neu5Ac hydroxylase (CMAH). However, humans lack this common mammalian cell surface molecule, Neu5Gc, due to inactivation of the CMAH gene ...
Deug-Nam Kwon   +2 more
doaj   +1 more source

Xenotransplantation Literature Update: January–June 2026

open access: yesXenotransplantation, Volume 33, Issue 4, July/August 2026.
ABSTRACT In the first half of 2026, xenotransplantation advanced through refinement rather than dramatic new clinical milestones. Clinical studies described graft physiology, immune infiltration, complement activation, coagulation incompatibility, and early function in living recipients, decedent models, and clinical islet xenotransplantation ...
Kasra Shirini   +3 more
wiley   +1 more source

Anti-Neu5Gc Antibody Kit Protocol - Western Blot v2

open access: yes, 2017
The Anti-Neu5Gc Antibody Kit contains the essential monospecific polyclonal chicken IgY antibody, along with a negative control primary antibody to detect the presence of Neu5Gc on glycoconjugates by Western blot (WB).
Kelsey Miller
core   +1 more source

Anti-Neu5Gc Antibody Kit Protocol - Western blot v1

open access: yes, 2016
The Anti-Neu5Gc Antibody Kit contains the essential monospecific polyclonal chicken IgY antibody, along with a negative control primary antibody to detect the presence of Neu5Gc on glycoconjugates by Western blot (WB).
Kelsey Miller
core   +1 more source

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