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The neural crest [PDF]

open access: yesCurrent Biology, 2003
It is generally accepted that the vertebrates evolved from protochordates ancestors, probably from an animal akin to modern day Amphioxus, a sessile filter feeder whose anatomical organisation is in many ways very similar to that of vertebrates. It has a dorsal nerve cord, a notochord, segmented muscle blocks and pharyngeal gill slits, but it lacks ...
openaire   +3 more sources

The neural crest and neural crest defects

open access: yesBiomedical Reviews, 2002
The neural crest is a fascinating embryonic tissue for more than one reason. In the adult organism it gives rise to an array of distinct cell types and tissues. It is responsible for many birth defects, familial diseases and malignancies, and it is amenable to the elucidation of mechanisms that regulate stem cell differentiation.
Zhi-Jian Zhang, Maya Sieber-Blum
openaire   +2 more sources

The heart of the neural crest: cardiac neural crest cells in development and regeneration [PDF]

open access: yesDevelopment, 2020
ABSTRACT Cardiac neural crest cells (cNCCs) are a migratory cell population that stem from the cranial portion of the neural tube. They undergo epithelial-to-mesenchymal transition and migrate through the developing embryo to give rise to portions of the outflow tract, the valves and the arteries of the heart.
Rajani M. George   +2 more
openaire   +3 more sources

The “beginnings” of the neural crest

open access: yesDevelopmental Biology, 2018
The neural crest has been the main object of my investigations during my career in science, up to now. It is a fascinating topic for an embryologist because of its two unique characteristics: its large degree of multipotency and the fact that its development involves a phase during which its component cells migrate all over the embryo and settle in ...
Le Douarin, Nicole, Dupin, Elisabeth
openaire   +4 more sources

Guidance of trunk neural crest migration requires neuropilin 2/semaphorin 3F signaling [PDF]

open access: yes, 2006
In vertebrate embryos, neural crest cells migrate only through the anterior half of each somite while avoiding the posterior half. We demonstrate that neural crest cells express the receptor neuropilin 2 (Npn2), while its repulsive ligand semaphorin 3F ...
Bronner-Fraser, Marianne   +3 more
core   +1 more source

SnapShot: Neural Crest

open access: yesCell, 2010
The neural crest is a transient population of cells that emerges from the neural tube during the early stages of embryonic development. Neural crest cells are unique to vertebrates and have properties similar to stem cells, including the ability to differentiate into many cell types (i.e., multipotency) and to regenerate.
Sauka-Spengler, T, Bronner, M
openaire   +3 more sources

Incremental evolution of the neural crest, neural crest cells and neural crest‐derived skeletal tissues [PDF]

open access: yesJournal of Anatomy, 2012
AbstractUrochordates (ascidians) have recently supplanted cephalochordates (amphioxus) as the extant sister taxon of vertebrates. Given that urochordates possess migratory cells that have been classified as ‘neural crest‐like’– and that cephalochordates lack such cells – this phylogenetic hypothesis may have significant implications with respect to the
J. Andrew Gillis, Brian K. Hall
openaire   +2 more sources

Dual function of Slit2 in repulsion and enhanced migration of trunk, but not vagal, neural crest cells [PDF]

open access: yes, 2003
Neural crest precursors to the autonomic nervous system form different derivatives depending upon their axial level of origin; for example, vagal, but not trunk, neural crest cells form the enteric ganglia of the gut.
Bronner-Fraser, Marianne   +2 more
core   +5 more sources

A novel spalt gene expressed in branchial arches affects the ability of cranial neural crest cells to populate sensory ganglia [PDF]

open access: yes, 2004
Cranial neural crest cells differentiate into diverse derivatives including neurons and glia of the cranial ganglia, and cartilage and bone of the facial skeleton.
Barembaum, Meyer   +1 more
core   +1 more source

Beta-actin is required for proper mouse neural crest ontogeny [PDF]

open access: yes, 2014
The mouse genome consists of six functional actin genes of which the expression patterns are temporally and spatially regulated during development and in the adult organism. Deletion of beta-actin in mouse is lethal during embryonic development, although
Ampe, Christophe   +3 more
core   +7 more sources

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