Results 1 to 10 of about 242,171 (188)
Pediatric Blood & Cancer, 2021 AbstractThe survival of patients with high‐risk neuroblastoma has improved significantly with the use of intensive multimodality treatment regimens, including chemotherapy, surgery, radiation therapy, myeloablative chemotherapy followed by stem cell rescue, and immunotherapy.
Christine Chung +7 more
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Why Is Aneuploidy Associated with Favorable Outcome in Neuroblastoma?
Biomolecules, 2021 Neuroblastoma is a pediatric cancer, onset with localized as well as metastatic disease. Localized tumors usually show a high content of aneuploid cells.
Gian Paolo Tonini
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Cell & Bioscience, 2022 Background In neuroblastoma, hyperactivation of the PI3K signaling pathway has been correlated with aggressive neuroblastomas, suggesting PI3Ks as promising targets for the treatment of neuroblastoma.
Yue Guo +9 more
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Autophagic flux inhibition enhances cytotoxicity of the receptor tyrosine kinase inhibitor ponatinib
Journal of Experimental & Clinical Cancer Research, 2020 Background Despite reported advances, acquired resistance to tyrosine kinase inhibitors still represents a serious problem in successful cancer treatment.
Diana Corallo +8 more
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TP53 and TP53-associated genes are correlated with the prognosis of paediatric neuroblastoma
BMC Genomic Data, 2022 Background TP53 is rarely mutated in paediatric neuroblastoma. The prognosis of TP53 and TP53-associated genes in paediatric neuroblastoma is unclear.
Haiwei Wang +3 more
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Italian Journal of Pediatrics, 2023 Background Genetic 1p deletion is reported in 30% of all neuroblastoma and is associated with the unfavorable prognosis of neuroblastoma. The expressions and prognosis of 1p candidate genes in neuroblastoma are unclear.
Haiwei Wang, Xinrui Wang, Liangpu Xu
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BMC Pediatrics, 2021 Background MYCN amplification and age are two critical prognostic factors of pediatric neuroblastoma. Previously, we had revealed the prognosis of MYCN target genes.
Haiwei Wang +4 more
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Journal of Experimental & Clinical Cancer Research, 2023 Background The repressor element-1 silencing transcription factor (REST), a master transcriptional repressor, is essential for maintenance, self-renewal, and differentiation in neuroblastoma.
Janardhan Keshav Karapurkar +9 more
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AKT inhibitor Hu7691 induces differentiation of neuroblastoma cells
Acta Pharmaceutica Sinica B, 2023 While neuroblastoma accounts for 15% of childhood tumor-related deaths, treatments against neuroblastoma remain scarce and mainly consist of cytotoxic chemotherapeutic drugs.
Shaowei Bing +12 more
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BMC Pediatrics, 2022 Background Previously, we had analyzed the prognosis of E2F transcription factors across adult tumor types. However, the expressions and prognosis of E2F transcription factors in pediatric neuroblastoma have not yet been fully studied.
Haiwei Wang +3 more
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