Results 11 to 20 of about 2,655 (162)
Neuroprotective effect of neuroglobin in hypoxia/ischemia [PDF]
Сибирский научный медицинский журнал, 2021 Neuroglobin is a representative of the globin group, an oxygen-binding protein which is predominantly expressed in the nervous system. Despite the large amount of conducted research, its role is still poorly understood.
E. V. Uzlova, S. M. Zimatkin
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Role of Neuroglobin in the Neuroprotective Actions of Estradiol and Estrogenic Compounds
Cells, 2021 Estradiol exerts neuroprotective actions that are mediated by the regulation of a variety of signaling pathways and homeostatic molecules. Among these is neuroglobin, which is upregulated by estradiol and translocated to the mitochondria to sustain ...
George E. Barreto +2 more
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Hyaluronate Nanoparticles as a Delivery System to Carry Neuroglobin to the Brain after Stroke [PDF]
Pharmaceutics, 2020 Therapies against stroke can restore the blood supply but cannot prevent the ischemic damage nor stimulate the recovery of the infarcted zone. The neuroglobin protein plays an important role in the neuro-regeneration process after stroke; however, the ...
Santos Blanco +7 more
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Neuroglobin over expressing mice: expression pattern and effect on brain ischemic infarct size. [PDF]
PLoS ONE, 2013 BACKGROUND: Stroke is a major cause of death and severe disability, but effective treatments are limited. Neuroglobin, a neuronal heme-globin, has been advocated as a novel pharmacological target in combating stroke and neurodegenerative disorders based ...
Zindy Raida +3 more
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Protection by neuroglobin expression in brain pathologies
Frontiers in Neurology, 2016 Astrocytes play an important role in physiological, metabolic and structural functions and, when impaired, they can be involved in various pathologies including Alzheimer, focal ischemic stroke and traumatic brain injury.
Eliana Baez +5 more
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Adaptations to hypoxia in the vertebrate retina. [PDF]
J PhysiolAbstract figure legend Most animals, including mammals, are susceptible to the damaging effects of hypoxia or ischaemia, where the result is neuronal cell death in the brain. By contrast, some neurons of the mammalian retina are less sensitive to hypoxia. In both brain and retina, neurons may survive if first preconditioned with ischaemia.
Jonz MG.
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Frontiers in Neurology, 2022 ObjectiveStroke is closely related to dementia, but there are few prospective studies on cognitive decline after stroke in patients with cerebral hemorrhage. Neuroglobin is an oxygen-binding protein mainly expressed in brain neurons.
Yu Gao, Bo Wang, Ye Miao, Yu Han
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Biophysical characterisation of neuroglobin of the icefish, a natural knockout for hemoglobin and myoglobin. Comparison with human neuroglobin. [PDF]
PLoS ONE, 2012 The Antarctic icefish Chaenocephalus aceratus lacks the globins common to most vertebrates, hemoglobin and myoglobin, but has retained neuroglobin in the brain. This conserved globin has been cloned, over-expressed and purified. To highlight similarities
Daniela Giordano +15 more
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Neurobiology of Disease, 2021 Mitochondrial diseases are among the most prevalent groups of inherited neurological disorders, affecting up to 1 in 5000 adults. Despite the progress achieved on the identification of gene mutations causing mitochondrial pathologies, they cannot be ...
Hélène Cwerman-Thibault +9 more
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Neuroglobin in Retinal Neurodegeneration: A Potential Target in Therapeutic Approaches
Cells, 2021 Retinal neurodegeneration affects an increasing number of people worldwide causing vision impairments and blindness, reducing quality of life, and generating a great economic challenge.
Virginia Solar Fernandez +2 more
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