Results 21 to 30 of about 3,008 (200)
Cytochrome b<sub>5</sub> reductase 4 efficiently reduces neuroglobin and cytoglobin. [PDF]
Free Radic Biol MedCytoglobin and Neuroglobin are heme-containing proteins expressed in most vertebrates, including mammals, with still not completely defined physiological roles.
DeMartino AW +13 more
europepmc +2 more sources
Electrochemical and Spectroscopic Characterization of Co-Neuroglobin: A Bioelectrocatalyst for H<sub>2</sub> Production. [PDF]
Inorg ChemThe electronic absorption, MCD, and RR spectra of the Co(III) and Co(II) derivatives of wild-type human neuroglobin (Co-WT) and its C46A/C55A mutant (Co–C46AC55A) were thoroughly investigated and compared with those of the corresponding Fe species and of
Meglioli M +9 more
europepmc +2 more sources
Neuroglobin in rat brain neurons
Сибирский научный медицинский журнал, 2021 Neuroglobin is a metalloprotein expressed predominantly in a nervous system and involved in the functioning of cells in normal and pathological conditions. Despite numerous studies, information on its regional distribution is ambiguous.
E. V. Uzlova, S. M. Zimatkin
doaj +1 more source
Neuroglobin regulates autophagy through mTORC1/RAPTOR/ULK-1 pathway in human neuroblastoma cells. [PDF]
Sci RepNeuroglobin (NGB) is a hexacoordinated hemeprotein mainly expressed in neurons. Following its upregulation and mitochondrial localization, NGB plays a pro-survival role against neuronal stress.
Manganelli V +12 more
europepmc +2 more sources
Neuroprotective effect of neuroglobin in hypoxia/ischemia
Сибирский научный медицинский журнал, 2021 Neuroglobin is a representative of the globin group, an oxygen-binding protein which is predominantly expressed in the nervous system. Despite the large amount of conducted research, its role is still poorly understood.
E. V. Uzlova, S. M. Zimatkin
doaj +1 more source
Frontiers in Neurology, 2022 ObjectiveStroke is closely related to dementia, but there are few prospective studies on cognitive decline after stroke in patients with cerebral hemorrhage. Neuroglobin is an oxygen-binding protein mainly expressed in brain neurons.
Yu Gao, Bo Wang, Ye Miao, Yu Han
doaj +1 more source
Role of Neuroglobin in the Neuroprotective Actions of Estradiol and Estrogenic Compounds
Cells, 2021 Estradiol exerts neuroprotective actions that are mediated by the regulation of a variety of signaling pathways and homeostatic molecules. Among these is neuroglobin, which is upregulated by estradiol and translocated to the mitochondria to sustain ...
George E. Barreto +2 more
doaj +1 more source
Neuroglobin, estrogens, and neuroprotection [PDF]
IUBMB Life, 2011 AbstractGlobins have been found in glial cells and neurons of invertebrates and vertebrates. The first nerve globin has been recognized in the nerve cord of the polychaete annelid Aphrodite aculeata in 1872. In some invertebrates, the nerve globin reaches a millimolar concentration which is likely sufficient to sustain the aerobic metabolism and thus ...
De Marinis, Elisabetta +2 more
openaire +2 more sources
Neuroglobin over expressing mice: expression pattern and effect on brain ischemic infarct size. [PDF]
PLoS ONE, 2013 BACKGROUND: Stroke is a major cause of death and severe disability, but effective treatments are limited. Neuroglobin, a neuronal heme-globin, has been advocated as a novel pharmacological target in combating stroke and neurodegenerative disorders based ...
Zindy Raida +3 more
doaj +1 more source
Neuroglobin: an endogenous neuroprotectant [PDF]
Current Opinion in Pharmacology, 2008 Cerebral hypoxia and ischemia trigger endogenous protective mechanisms that can prevent or limit brain damage. Understanding these mechanisms may lead to new therapeutic strategies for stroke and related disorders. Neuroglobin (Ngb), a recently discovered protein that is distantly related to hemoglobin and myoglobin, is expressed predominantly in brain
David A, Greenberg +2 more
openaire +2 more sources