Results 41 to 50 of about 3,990 (214)
Neuroglobin Protection in Retinal Ischemia [PDF]
Investigative Opthalmology & Visual Science, 2012 Neuroglobin (Ngb) is a vertebrate globin that is predominantly expressed in the retina and brain. To explore the role of Ngb in retinal neuroprotection during ischemia reperfusion (IR), the authors examined the effect of Ngb overexpression in the retina in vivo by using Ngb-transgenic (Ngb-Tg) mice.Retinal IR was induced in Ngb overexpressing Ngb-Tg ...
Anita S Y, Chan +4 more
openaire +2 more sources
Research on the Effects of Neuroglobin on Ferroptosis in the Nerve Cells
Chinese Medicine and Natural Products, 2023 Objectives The objective of this article was to explore the effects of neuroglobin (NGB) on ferroptosis in the nerve cells.
Wenjin Gao +4 more
doaj +1 more source
Identification of a novel distal regulatory element of the human Neuroglobin gene by the chromosome conformation capture approach [PDF]
, 2017 Neuroglobin (NGB) is predominantly expressed in the brain and retina. Studies suggest that NGB exerts protective effects to neuronal cells and is implicated in reducing the severity of stroke and Alzheimer's disease.
Chan, G.C.F. (Godfrey Chi Fung) +8 more
core +2 more sources
Redox and Peroxidase Activities of the Hemoglobin Superfamily: Relevance to Health and Disease [PDF]
, 2016 Significance: Erythrocyte hemoglobin (Hb) and myocyte myoglobin, although primarily oxygen-carrying proteins, have the capacity to do redox chemistry. Such redox activity in the wider family of globins now appears to have important associations with the ...
Brandon J. Reeder +5 more
core +1 more source
Neural Regeneration Research, 2021 Neuroglobin (Ngb) is a 17 kDa monomeric hexa-coordinated heme protein belonging to the globin family. Ngb is mainly expressed in neurons of the central and peripheral nervous system, although moderate levels of Ngb have been detected in non-nervous tissues.
Ciccone L. +3 more
openaire +3 more sources
Ultrafast photochemistry of the bc₁ complex [PDF]
, 2017 We present a full investigation of ultrafast light-induced events in the membraneous cytochrome bc 1 complex by transient absorption spectroscopy.
Baymann +35 more
core +8 more sources
Comparative genomics of neuroglobin reveals its early origins. [PDF]
PLoS ONE, 2012 Neuroglobin (Ngb) is a hexacoordinated globin expressed mainly in the central and peripheral nervous system of vertebrates. Although several hypotheses have been put forward regarding the role of neuroglobin, its definite function remains uncertain.
Jasmin Dröge +3 more
doaj +1 more source
Cardiolipin drives cytochrome c proapoptotic and antiapoptotic actions [PDF]
, 2011 ""\\"Cytochrome c (cytc) is pivotal in mitochondrial respiration and apoptosis. The heme-Fe-atom of native hexacoordinated horse heart cytc (hhcytc) displays a very low reactivity toward ligands and does not exhibit catalytic properties.
Ascenzi, P +4 more
core +1 more source
Conformational Dynamics in Neuroglobin [PDF]
Biophysical Journal, 2011 Neuroglobin (Ngb) is a heme protein that belongs to the family of hexacoordinated hemoglobins. The physiological role of this protein is not well understood, but several plausible functions have been proposed such as oxygen carrier, oxygen sensor, NO scavenger and protectant against oxidative damage. To understand the mechanism of Ngb interactions with
Astudillo, Luisana +4 more
openaire +1 more source
THE ROLE OF NEUROGLOBIN IN CEREBRAL ISCHEMIA / HYPOXIA AND OTHER NEUROPATHOLOGY
Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018 The aim of the study was to summarize literature data on the localization, functions and role of neuroglobin in ischemia / hypoxia of the brain and neuropathology of different genesis.
Zimatkin S. M. +2 more
doaj +1 more source