Results 51 to 60 of about 2,655 (162)
Medicine ScienceObjective criteria are essential in forensic toxicology for elucidating combustion-related deaths. Carbon monoxide (CO) and carbon dioxide (CO₂) impair oxygen delivery by competing with oxygen for hemoglobin binding and by disrupting cellular oxidative ...
Mustafa Dogan +8 more
doaj +1 more source
Antioxidants, 2021 Prunus cerasoides (PC) has been reported to have antimicrobial and anti-inflammatory properties, but its potential as a neuroprotective agent in a mouse model of cerebral ischemia has not been explored.
So-Dam Kim +5 more
doaj +1 more source
Recent Cutting‐Edge Technologies for the Delivery of Peptide Nucleic Acid
Chemistry – A European Journal, Volume 31, Issue 34, June 17, 2025.This review provides an overview of PNA cellular delivery methods, starting with traditional peptide‐based systems and progressing to advanced approaches using nanoparticles, liposomes, and calixarene. It highlights how these innovative strategies have opened the way for more effective and efficient PNA delivery, ultimately enhancing the potential for ...
Concetta Avitabile +4 more
wiley +1 more source
British Journal of Haematology, Volume 206, Issue 6, Page 1585-1592, June 2025.Globally, sickle cell disease (SCD) is the most common inherited haemoglobinopathy. The highest burden of SCD is encountered in low‐ and middle‐income countries (LMICs), most of which lack the resources to contend with the disease. Blood transfusion remains central to the emergent treatment and prevention of complications of SCD.
Jeremy W. Jacobs +13 more
wiley +1 more source
Neuroglobin Can Prevent or Reverse Glaucomatous Progression in DBA/2J Mice
Molecular Therapy: Methods & Clinical Development, 2017 Mitochondrial dysfunction is responsible for hereditary optic neuropathies. We wished to determine whether preserving mitochondrial bioenergetics could prevent optic neuropathy in a reliable model of glaucoma.
Hélène Cwerman-Thibault +12 more
doaj +1 more source
Brain and Behavior, 2020 Background The neuroglobin (Ngb) is well recognized as a potential biomarker for the hypoxic‐ischemic brain injury. However, connection between Ngb and delayed cerebral ischemia (DCI) following aneurysmal subarachnoid hemorrhage (aSAH) is still unclear ...
Chenyu Ding +7 more
doaj +1 more source
Brain and Behavior, Volume 15, Issue 4, April 2025.ABSTRACT Purpose Patients undergoing open‐heart surgery often face significant challenges in postoperative cognitive dysfunction (POCD). There has been growing interest in understanding how anesthesia medications, such as dexmedetomidine (DEX) and midazolam, impact cognitive function in these patients.
Masoomeh Tabari +3 more
wiley +1 more source
Human neuroglobin: crystals and preliminary X-ray diffraction analysis [PDF]
, 2002 Neuroglobin, a recently discovered member of the haemoglobin superfamily, is primarily expressed in the brain of humans and other vertebrates, where it has been proposed to enhance O(2) supply in response to hypoxia or ischaemia, protecting the neuron ...
M. Bolognesi +31 more
core +1 more source
Frontiers in Neuroscience, 2020 In humans, a considerable number of the autopsy samples of cognitively normal individuals aged between 57 and 102 years have revealed the presence of amyloid plaques, one of the typical signs of AD, indicating that many of us use mechanisms that defend ...
Silvia de Vidania +11 more
doaj +1 more source
Iron‐Histidine Coordination in Cytochrome b5: A Local Vibrational Mode Study
ChemPhysChem, Volume 26, Issue 7, April 1, 2025.Distal/proximal FeN bond strength and axial NFeN angle stiffness in a series of cytochrome b5s, isolated from different species such as bacteria, animals, and human were investigated with our local vibrational mode analysis combined with QM/MM calculations.
Marek Freindorf +2 more
wiley +1 more source