Results 71 to 80 of about 3,008 (200)

Proteome data of neuroblastoma cells overexpressing Neuroglobin

Data in Brief, 2022
In this article, we present data on the proteome of human neuroblastoma cells stably overexpressing Neuroglobin (NGB). The neuroprotective role of NGB is clearly established, nevertheless the related mechanistic processes, which are dependent on NGB ...
M. Costanzo, M. Caterino, I. Salvatori, V. Manganelli, A. Ferri, R. Misasi, M. Ruoppolo   +6 more
semanticscholar   +1 more source

Effects of Midazolam and Dexmedetomidine on Cognitive Dysfunction Following Open‐Heart Surgery: A Comprehensive Review

Brain and Behavior, Volume 15, Issue 4, April 2025.
ABSTRACT Purpose Patients undergoing open‐heart surgery often face significant challenges in postoperative cognitive dysfunction (POCD). There has been growing interest in understanding how anesthesia medications, such as dexmedetomidine (DEX) and midazolam, impact cognitive function in these patients.
Masoomeh Tabari, Ali Moradi, Golbon Asalforoush Rezaieh, Malihe Aghasizadeh   +3 more
wiley   +1 more source

Design and Specificity Test of Specific Primers for Neuroglobin Gene Expression Modulation in Brain Tissue of Rattus norvegicus using qRT-PCR

BioScience, 2023
. Neuroglobin (Ngb) is a newly discovered globin that is found in large numbers in neurons. Brain cells are very sensitive to lack of oxygen and can begin to die within five minutes after the oxygen supply is cut off.
Bintang Fadhil Ramadhan, Muhammad Farikh, Muhammad Naufal Arrafi, Nagra Aulia Valofi, Walidatul Awaliyah, Jessi Rizkanauli Simangungsong, Dini Herisanti, S. Farma   +7 more
semanticscholar   +1 more source

Changes in biochemical and molecular genetic parameters in rats exposed to carbon dioxide and carbon monoxide

Medicine Science
Objective criteria are essential in forensic toxicology for elucidating combustion-related deaths. Carbon monoxide (CO) and carbon dioxide (CO₂) impair oxygen delivery by competing with oxygen for hemoglobin binding and by disrupting cellular oxidative ...
Mustafa Dogan, Osman Celbis, Mucahit Oruc, Osman Ciftci, Yilmaz Cigremis, Asli Cetin, Nese Basak Turkmen, Saim Yologlu, Yunus Karakoc   +8 more
doaj   +1 more source

Neuroglobin overexpression in cerebellar neurons of Harlequin mice improves mitochondrial homeostasis and reduces ataxic behavior. [PDF]

Mol Ther
Neuroglobin, a member of the globin superfamily, is abundant in the brain, retina, and cerebellum of mammals and localizes to mitochondria. The protein exhibits neuroprotective capacities by participating in electron transfer, oxygen supply, and ...
Cwerman-Thibault H, Malko-Baverel V, Le Guilloux G, Ratcliffe E, Mouri D, Torres-Cuevas I, Millán I, Saubaméa B, Mignon V, Boespflug-Tanguy O, Gressens P, Corral-Debrinski M.   +11 more
europepmc   +2 more sources

Iron‐Histidine Coordination in Cytochrome b5: A Local Vibrational Mode Study

ChemPhysChem, Volume 26, Issue 7, April 1, 2025.
Distal/proximal FeN bond strength and axial NFeN angle stiffness in a series of cytochrome b5s, isolated from different species such as bacteria, animals, and human were investigated with our local vibrational mode analysis combined with QM/MM calculations.
Marek Freindorf, Kevin Fleming, Elfi Kraka   +2 more
wiley   +1 more source

Neuroprotective Effect of Neuroglobin in Simultaneous Incomplete Ischemia

Psychiatry and Psychological Disorders, 2023
The role of neuroglobin in ischemia has not been studied in detail. A number of studies indicate its neuroprotective effect, other data refute its importance for the survival of neurons in conditions of lack of oxygen.
E. Bon'
semanticscholar   +1 more source

Neuroglobin Can Prevent or Reverse Glaucomatous Progression in DBA/2J Mice

Molecular Therapy: Methods & Clinical Development, 2017
Mitochondrial dysfunction is responsible for hereditary optic neuropathies. We wished to determine whether preserving mitochondrial bioenergetics could prevent optic neuropathy in a reliable model of glaucoma.
Hélène Cwerman-Thibault, Christophe Lechauve, Sébastien Augustin, Delphine Roussel, Élodie Reboussin, Ammara Mohammad, Julie Degardin-Chicaud, Manuel Simonutti, Hong Liang, Françoise Brignole-Baudouin, Anne Maron, Thomas Debeir, Marisol Corral-Debrinski   +12 more
doaj   +1 more source

Early stage neuroglobin level as a predictor of delayed cerebral ischemia in patients with aneurysmal subarachnoid hemorrhage

Brain and Behavior, 2020
Background The neuroglobin (Ngb) is well recognized as a potential biomarker for the hypoxic‐ischemic brain injury. However, connection between Ngb and delayed cerebral ischemia (DCI) following aneurysmal subarachnoid hemorrhage (aSAH) is still unclear ...
Chenyu Ding, Dezhi Kang, Pengqiang Chen, Ziliang Wang, Yuanxiang Lin, Dengliang Wang, Zhangya Lin, Jianjun Gu   +7 more
doaj   +1 more source

Arginine metabolism is a biomarker of red blood cell and human aging

Aging Cell, Volume 24, Issue 2, February 2025.
Reisz et al. examined age‐related changes in erythrocyte metabolism using 15,700 specimens from 13,757 individuals across four cohorts, including healthy donors and sickle cell disease patients. The study identifies alterations in arginine metabolism associated with chronological age, linking them to erythrocyte function, vesiculation, and post ...
Julie A. Reisz, Eric J. Earley, Travis Nemkov, Alicia Key, Daniel Stephenson, Gregory R. Keele, Monika Dzieciatkowska, Steven L. Spitalnik, Eldad A. Hod, Steven Kleinman, Nareg H. Roubinian, Mark T. Gladwin, Kirk C. Hansen, Philip J. Norris, Michael P. Busch, James C. Zimring, Gary A. Churchill, Grier P. Page, Angelo D'Alessandro   +18 more
wiley   +1 more source