Results 81 to 90 of about 3,008 (200)

Effects of Neuroglobin in Cerebral Ischemia and Introduction of Omega-3 Polyunsaturated Fatty Acids

Psychiatry and Psychological Disorders, 2023
The aim of the work was to evaluate the content of neuroglobin in the brain of rats with cerebral ischemia and under the conditions of administration of omega-3 polyunsaturated fatty acids.
Lizaveta I. Bon
semanticscholar   +1 more source

Effects of patent foramen ovale in migraine: a metabolomics‐based study

The Journal of Physiology, Volume 603, Issue 4, Page 809-835, 15 February 2025.
Abstract figure legend Aura, cystatin‐C and calcium are biomarkers of PFO in migraine. PFO closure relieves migraine by regulating 5‐HT metabolism and redox reactions, especially in the posterior head. cTTE, contrast‐transthoracic echocardiography; DESI‐MSI, desorption electrospray ionization mass imaging; H&E, haematoxylin and eosin; PFO, patent ...
Bosi Dong, Xin Li, Lu Zhang, Ge Liang, Wen Zheng, Luolan Gui, Shuming Ji, Yusha Tang, Hua Li, Wanling Li, Ruiqi Yang, Yajiao Li, Anjiao Peng, Yucheng Chen, Meng Gong, Lei Chen   +15 more
wiley   +1 more source

Ligand pathways in neuroglobin revealed by low-temperature photodissociation and docking experiments

IUCrJ, 2019
A combined biophysical approach was applied to map gas-docking sites within murine neuroglobin (Ngb), revealing snapshots of events that might govern activity and dynamics in this unique hexacoordinate globin, which is most likely to be involved in gas ...
Chiara Ardiccioni, Alessandro Arcovito, Stefano Della Longa, Peter van der Linden, Dominique Bourgeois, Martin Weik, Linda Celeste Montemiglio, Carmelinda Savino, Giovanna Avella, Cécile Exertier, Philippe Carpentier, Thierry Prangé, Maurizio Brunori, Nathalie Colloc'h, Beatrice Vallone   +14 more
doaj   +1 more source

Overexpression of Neuroglobin Promotes Energy Metabolism and Autophagy Induction in Human Neuroblastoma SH-SY5Y Cells

Cells, 2021
Neuroglobin (NGB) is an O2-binding globin mainly expressed in the central and peripheral nervous systems and cerebrospinal fluid. Previously, it was demonstrated that NGB overexpression protects cells from hypoxia-induced death.
Valeria Manganelli, Illari Salvatori, Michele Costanzo, Antonella Capozzi, Daniela Caissutti, Marianna Caterino, Cristiana Valle, Alberto Ferri, Maurizio Sorice, Margherita Ruoppolo, Tina Garofalo, Roberta Misasi   +11 more
doaj   +1 more source

Dexmedetomidine Mediates Neuroglobin Up-Regulation and Alleviates the Hypoxia/Reoxygenation Injury by Inhibiting Neuronal Apoptosis in Developing Rats

Frontiers in Pharmacology, 2020
BackgroundExploring the effective therapy for neonatal hypoxic-ischemic brain injury is an important goal. This study was designed to investigate how dexmedetomidine (DEX) contribute to hypoxic brain injury.MethodsDeveloping Sprague-Dawley rat models of ...
Yan Gao, Yongfang Zhang, Yunxia Dong, Xiuying Wu, Hongtao Liu   +4 more
doaj   +1 more source

The role of microglia in neurocognitive deficits induced by general anaesthetic agents during neurodevelopment

Clinical and Translational Discovery, Volume 4, Issue 6, December 2024.
Under GAAs, microglia are activated towards M1 (pro‐inflammatory) phenotype through direct and indirect ways. Microglia‐mediated neuroinflammation induce neuronal death, synaptic loss and dysmyelination in developing brain, which might be a key mechanism of neurocognitive deficits during neurodevelopment.
Xinyue Liang, Fang Fang, Xiaoqing Wang, Ming Jiang, Jing Cang   +4 more
wiley   +1 more source

Molecularly Imprinted Nanoparticle‐Based Polymer (Acrylamide‐N‐Vinyl imidazole)/Nafion Film Modified Screen‐Printed Electrode System for Rapid Determination of Hemoglobin

Electroanalysis, Volume 36, Issue 12, December 2024.
Abstract In medical diagnostics, variations in hemoglobin levels can reveal a variety of prevalent health conditions. Abnormal hemoglobin is known to be connected with diseases like anemia, diabetes, hematemesis, hematuria, and hemoglobinuria. Consequently, there is a significant demand for advanced detection technologies and precise methodologies to ...
Hilal Özçelik, Esra Yaşar, Timuçin Güner, Emre Dokuzparmak, Koray Şarkaya, Sinan Akgöl   +5 more
wiley   +1 more source

Progress on the Mechanisms and Neuroprotective Benefits of Dexmedetomidine in Brain Diseases

Brain and Behavior, Volume 14, Issue 11, November 2024.
Dexmedetomidine has demonstrated potent neuroprotective effects in a variety of brain disorders, and this may be achieved by inhibiting inflammatory responses, attenuating oxidative stress, reducing apoptosis and autophagy, and improving the immune microenvironment.
Zhenxing Tao, Pengpeng Li, Xudong Zhao
wiley   +1 more source

Neuroglobin and Cytoglobin: Genes, Proteins and Evolution [PDF]

IUBMB Life, 2004
AbstractHemoglobin and myoglobin are oxygen transport and storage proteins of most vertebrates. Neuroglobin (Ngb) and cytoglobin (Cygb) ‐ two recent additions to the vertebrate globin superfamily ‐ have still disputed functions. Combining the data from all available resources, we investigate the evolution of these novel globins.
Thorsten, Burmester, Mark, Haberkamp, Stephanie, Mitz, Anja, Roesner, Marc, Schmidt, Bettina, Ebner, Frank, Gerlach, Christine, Fuchs, Thomas, Hankeln   +8 more
openaire   +2 more sources

Cardiopulmonary adaptations of a diving marine mammal, the bottlenose dolphin: Physiology during anesthesia

Physiological Reports, Volume 12, Issue 17, September 2024.
Abstract Diving marine mammals are a diverse group of semi‐ to completely aquatic species. Some species are targets of conservation and rehabilitation efforts; other populations are permanently housed under human care and may contribute to clinical and biomedical investigations.
Carolina R. Le‐Bert, Gordon S. Mitchell, Leah R. Reznikov   +2 more
wiley   +1 more source