Results 61 to 70 of about 3,990 (214)
Molecules, 2021 Neuroglobin (NGB) is a myoglobin-like monomeric globin that is involved in several processes, displaying a pivotal redox-dependent protective role in neuronal and extra-neuronal cells. NGB remarkably exerts its function upon upregulation by NGB inducers,
Michele Costanzo +5 more
doaj +1 more source
Immobilization of proteins in silica gel: Biochemical and biophysical properties [PDF]
, 2015 The development of silica-based sol-gel techniques compatible with the retention of protein structure and function started more than 20 years ago, mainly for the design of biotechnological devices or biomedical applications.
Abbruzzetti, S +8 more
core +1 more source
Neuroglobin: A New Possible Marker of Estrogen-Responsive Breast Cancer
Cells, 2021 The expression of the α-subtype of Estrogen Receptor (ERα) characterizes most breast cancers (more than 75%), for which endocrine therapy is the mainstay for their treatment.
Virginia Solar Fernandez +8 more
doaj +1 more source
Characterization of novel glomerular proteins : role in physiology and disease [PDF]
, 2014 Glomerular damage accounts for the majority of chronic kidney disease cases, the prevalence of which is dramatically escalating worldwide, mainly due to increase in diabetes and associated nephropathy.
Andersson, Ann-Charlotte
core +1 more source
Structural and (Pseudo-)Enzymatic Properties of Neuroglobin: Its Possible Role in Neuroprotection
Cells, 2021 Neuroglobin (Ngb), the third member of the globin family, was discovered in human and murine brains in 2000. This monomeric globin is structurally similar to myoglobin (Mb) and hemoglobin (Hb) α and β subunits, but it hosts a bis-histidyl six-coordinated
Giovanna De Simone +5 more
doaj +1 more source
Journal of Extracellular Vesicles, Volume 14, Issue 12, December 2025.ABSTRACT In neurones, like in any other cell, their function often relies on the fine‐tuning of their protein levels, which is achieved by the balance between protein synthesis and turnover. Defects in protein homeostasis frequently lead to neuronal dysfunction and neurological disorders.
María Gamarra +7 more
wiley +1 more source
Applied Sciences, 2022 The present work shows the biochemical and structural fundamentals for the stress induced anxiety and stress adjustment response of the CA3 hippocampus area.
Vlad-Alexandru Toma +7 more
doaj +1 more source
Antioxidants, 2021 Prunus cerasoides (PC) has been reported to have antimicrobial and anti-inflammatory properties, but its potential as a neuroprotective agent in a mouse model of cerebral ischemia has not been explored.
So-Dam Kim +5 more
doaj +1 more source
Hyperthermal stability of neuroglobin and cytoglobin [PDF]
The FEBS Journal, 2005 Neuroglobin (Ngb) and cytoglobin (Cygb), recent additions to the globin family, display a hexa‐coordinated (bis‐histidyl) heme in the absence of external ligands. Although these proteins have the classical globin fold they reveal a very high thermal stability with a melting temperature (Tm) of 100 °C for Ngb and 95 °C for Cygb.
Hamdane, Djemel +7 more
openaire +3 more sources
International Journal of Developmental Neuroscience, Volume 85, Issue 5, August 2025.We investigated the regulatory effects of seizure‐induced excitotoxicity and acute hypoxia on the cytoprotective activin A and Ngb systems in the developing mouse brain. Our results demonstrate the differential regulation of Ngb and activin A as a function of time and type of injury and suggest their potential role as biomarkers of excitotoxic and ...
Clara Becker +2 more
wiley +1 more source