Results 61 to 70 of about 3,008 (200)
Prunus cerasoides (PC) has been reported to have antimicrobial and anti-inflammatory properties, but its potential as a neuroprotective agent in a mouse model of cerebral ischemia has not been explored.
So-Dam Kim +5 more
doaj +1 more source
Is neuroglobin a signal transducer? [PDF]
[No abstract available]
GIUFFRE', ALESSANDRO +3 more
openaire +3 more sources
ABSTRACT In neurones, like in any other cell, their function often relies on the fine‐tuning of their protein levels, which is achieved by the balance between protein synthesis and turnover. Defects in protein homeostasis frequently lead to neuronal dysfunction and neurological disorders.
María Gamarra +7 more
wiley +1 more source
An efficient system for the biosynthesis, isolation and purification of recombinant human neuroglobin has been developed and optimized, which makes it possible to produce protein in quantities sufficient to study its properties.
M. Semenova +11 more
semanticscholar +1 more source
We investigated the regulatory effects of seizure‐induced excitotoxicity and acute hypoxia on the cytoprotective activin A and Ngb systems in the developing mouse brain. Our results demonstrate the differential regulation of Ngb and activin A as a function of time and type of injury and suggest their potential role as biomarkers of excitotoxic and ...
Clara Becker +2 more
wiley +1 more source
Conformational Dynamics in Neuroglobin [PDF]
Neuroglobin (Ngb) is a heme protein that belongs to the family of hexacoordinated hemoglobins. The physiological role of this protein is not well understood, but several plausible functions have been proposed such as oxygen carrier, oxygen sensor, NO scavenger and protectant against oxidative damage. To understand the mechanism of Ngb interactions with
Astudillo, Luisana +4 more
openaire +1 more source
Recent Cutting‐Edge Technologies for the Delivery of Peptide Nucleic Acid
This review provides an overview of PNA cellular delivery methods, starting with traditional peptide‐based systems and progressing to advanced approaches using nanoparticles, liposomes, and calixarene. It highlights how these innovative strategies have opened the way for more effective and efficient PNA delivery, ultimately enhancing the potential for ...
Concetta Avitabile +4 more
wiley +1 more source
Peptide nucleic acid (PNA) is a DNA mimic that shows good stability against nucleases and proteases, forming strongly recognized complementary strands of DNA and RNA. However, due to its feeble ability to cross the cellular membrane, PNA activity and its
A. Falanga +10 more
semanticscholar +1 more source
Globally, sickle cell disease (SCD) is the most common inherited haemoglobinopathy. The highest burden of SCD is encountered in low‐ and middle‐income countries (LMICs), most of which lack the resources to contend with the disease. Blood transfusion remains central to the emergent treatment and prevention of complications of SCD.
Jeremy W. Jacobs +13 more
wiley +1 more source
What is the function of neuroglobin? [PDF]
SUMMARY For a long time, haemoglobin and myoglobin had been assumed to represent the only globin types of vertebrates. In 2000, however, we discovered a third globin type by mining the genome sequence data. Based on a preferential expression in the nervous system, this globin is referred to as neuroglobin. Despite nine years of research,
Thorsten, Burmester, Thomas, Hankeln
openaire +2 more sources

