Results 31 to 40 of about 2,655 (162)

Comparative genomics of neuroglobin reveals its early origins. [PDF]

open access: yesPLoS ONE, 2012
Neuroglobin (Ngb) is a hexacoordinated globin expressed mainly in the central and peripheral nervous system of vertebrates. Although several hypotheses have been put forward regarding the role of neuroglobin, its definite function remains uncertain.
Jasmin Dröge   +3 more
doaj   +1 more source

Intravitreal Neuroglobin Mitigates Primate Experimental Glaucomatous Structural Damage in Association with Reduced Optic Nerve Microglial and Complement 3-Astrocyte Activation

open access: yesBiomolecules, 2023
Current management of glaucomatous optic neuropathy is limited to intraocular pressure control. Neuroglobin (Ngb) is an endogenous neuroprotectant expressed in neurons and astrocytes.
Anita S. Y. Chan   +9 more
doaj   +1 more source

Neuroglobin and cytoglobin: two new members of globin family

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2011
The globin family has long been defined by myoglobin and hemoglobin, proteins with the functions of oxygen storage and transportation, respectively. Recently, two new members of this family were discovered: neuroglobin present in neurons and retinal ...
Priscilla Tosqui   +1 more
doaj   +1 more source

Neuroglobin, a factor playing for nerve cell survival [PDF]

open access: yes, 2016
Cell death represents the final outcome of several pathological conditions of the central nervous system and available evidence suggests that in both acute injuries and neurodegenerative diseases it is often associated with mitochondrial dysfunction ...
GUIDOLIN, DIEGO   +9 more
core   +1 more source

Connecting the Dots in the Neuroglobin-Protein Interaction Network of an Unstressed and Ferroptotic Cell Death Neuroblastoma Model

open access: yesCells, 2019
Neuroglobin is a heme protein of which increased levels provide neuroprotection against amyloid proteinopathy and hemorrhagic damage. These cellular stressors involve the promotion of ferroptosis—an iron-dependent, lipid peroxide-accreting form of ...
Zoë P. Van Acker   +7 more
doaj   +1 more source

Neuroglobin, seven years after

open access: yes, 2007
Neuroglobin is expressed in vertebrates brain and belongs to a branch of the globin family that diverged early in evolution. Sequence conservation suggests a relevant role in the nervous system, with tight structural restraints.
VALLONE, Beatrice, BRUNORI, Maurizio
core   +1 more source

Overexpression of Neuroglobin Promotes Energy Metabolism and Autophagy Induction in Human Neuroblastoma SH-SY5Y Cells

open access: yesCells, 2021
Neuroglobin (NGB) is an O2-binding globin mainly expressed in the central and peripheral nervous systems and cerebrospinal fluid. Previously, it was demonstrated that NGB overexpression protects cells from hypoxia-induced death.
Valeria Manganelli   +11 more
doaj   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

open access: yesAdvanced Science, Volume 13, Issue 55, 5 October 2026.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo   +18 more
wiley   +1 more source

Structure and function of hemoproteins from cold-adapted organism [PDF]

open access: yes, 2011
Environmental oxygen availability certainly plays a key role in the evolution of polar marine life, as suggested by the physiological and biochemical strategies that the organisms have adopted to acquire, deliver and scavenge oxygen.
Russo, Roberta
core   +1 more source

Neuroglobin Content in Rat Brain Structures after Subtotal Cerebral Ischemia

open access: yesУчёные записки Казанского университета: Серия Естественные науки, 2023
Neuroglobin (Ngb) is a member of the globin family. Like other globin proteins, it is involved in the maintenance of oxygen homeostasis. Ngb distribution in the normal brain is well known, but its response to pathological injury, such as cerebral ...
E. V. Uzlova, S. M. Zimatkin, E. I. Bon
doaj   +1 more source

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