Results 41 to 50 of about 6,060 (200)

Neuroinvasion and Viral Reservoir in COVID-19 [PDF]

Cureus, 2020
The new coronavirus disease 2019 (COVID-19) has a remarkably high transmissibility potential and sometimes invades the central nervous system (CNS). The study of the involvement of the nervous system in the pathogenesis of the disease is especially interesting.
Altable Pérez, Marcos, De la Serna, Juan Moises   +1 more
openaire   +2 more sources

Genetic determinants of Sindbis virus neuroinvasiveness [PDF]

Journal of Virology, 1997
After peripheral inoculation of mice, Sindbis virus replicates in a variety of tissues, leading to viremia. In some cases, the virus can enter the central nervous system (CNS) and cause lethal encephalitis. The outcome of infection is age and virus strain dependent.
J, Dubuisson, S, Lustig, N, Ruggli, Y, Akov, C M, Rice   +4 more
openaire   +2 more sources

A Systematic Review on Neurological Aspects of COVID-19: Exploring the Relationship Between COVID-19-Related Olfactory Dysfunction and Neuroinvasion

Frontiers in Neurology, 2022
ObjectivesTo identify neurological aspects of Coronavirus disease 2019 (COVID-19) and to investigate COVID-19 infected patients with and without olfactory dysfunction in relation to polymerase chain reaction (PCR) assay results for severe acute ...
Sujata Purja, SuA Oh, EunYoung Kim, EunYoung Kim   +3 more
doaj   +1 more source

Alteration of B-cell subsets enhances neuroinvasion in mouse scrapie infection [PDF]

, 2008
Acquired forms of prion diseases or transmissible spongiform encephalopathies are believed to occur following peripheral exposure. Prions initially accumulate in the lymphoid system before spreading to the nervous system, but the underlying mechanisms ...
Raymond Bujdoso, Michael A. Klein, Harry Harms, Adriano Aguzzi, Klein, M A, Aguzzi, A; https://orcid.org/, Petra Schwarz, Flechsig, E, Hoffmann, T, von Poser-Klein, C, Bujdoso, R, Tanja Hoffmann, Schwarz, P, Harms, H, Eckhard Flechsig, Christine von Poser-Klein, Harms, Harry, von Poser-Klein, Christine, Aguzzi, Adriano, Klein, Michael A., Flechsig, Eckhard, Bujdoso, Raymond, Hoffmann, Tanja, Schwarz, Petra   +23 more
core   +1 more source

COVID-19, Neuropathology, and Aging: SARS-CoV-2 Neurological Infection, Mechanism, and Associated Complications

Frontiers in Aging Neuroscience, 2021
The spectrum of health complications instigated by coronavirus disease 2019 (COVID-19, caused by the novel severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2) pandemic has been diverse and complex.
Rajkumar Singh Kalra, Jaspreet Kaur Dhanjal, Avtar Singh Meena, Vishal C. Kalel, Surya Dahiya, Birbal Singh, Saikat Dewanjee, Ramesh Kandimalla, Ramesh Kandimalla   +8 more
doaj   +1 more source

Guinea Pigs Are Not a Suitable Model to Study Neurological Impacts of Ancestral SARS-CoV-2 Intranasal Infection

Viruses
Neurological symptoms involving the central nervous system (CNS) and peripheral nervous system (PNS) are common complications of acute COVID-19 as well as post-COVID conditions.
Jonathan D. Joyce, Greyson A. Moore, Christopher K. Thompson, Andrea S. Bertke   +3 more
doaj   +1 more source

HSV-1 Neuroinvasiveness

Intervirology, 1993
Neuroinvasiveness, the capacity of virus to enter and progress through the nervous system, may be accomplished by hematogenous or neural routes. We have been interested in defining HSV-1 genes specifically concerned with the neural pathway. In one system (involving HSV strain Ang), we have found that a single amino acid change in glycoprotein D, a ...
openaire   +2 more sources

Enhanced neuroinvasion by smaller, soluble prions [PDF]

Acta Neuropathologica Communications, 2017
Infectious prion aggregates can propagate from extraneural sites into the brain with remarkable efficiency, likely transported via peripheral nerves. Yet not all prions spread into the brain, and the physical properties of a prion that is capable of transit within neurons remain unclear. We hypothesized that small, diffusible aggregates spread into the
Bett, Cyrus, Lawrence, Jessica, Kurt, Timothy D, Orru, Christina, Aguilar-Calvo, Patricia, Kincaid, Anthony E, Surewicz, Witold K, Caughey, Byron, Wu, Chengbiao, Sigurdson, Christina J   +9 more
openaire   +5 more sources

Poster: SARS-CoV-2 Neuroinvasion [PDF]

, 2021
Over the last century, science and literature has reported neurological manifestations during various disease outbreaks as well as long-term sequelae following epidemics and pandemics.
Tatusko, Heather M
core  

COVID‐19 Amplifies Sex‐Specific Dopamine and Glial Responses in a Parkinson's Disease Mouse Model

Movement Disorders, EarlyView.
Abstract Background Exposure to environmental agents, including viral infections, may increase Parkinson's disease (PD) susceptibility, especially in males, but the neurodegenerative risk extent of COVID‐19 remains uncertain. Objectives We investigated the plausible link between severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and
Ifeoluwa Awogbindin, Mélanie Bourque, Marc Morissette, Marie‐Ève Hamelin, Chantal Rhéaume, Jared VanderZwaag, Antonia Landwehr, Disha Patel, Guy Boivin, Marie‐Ève Tremblay, Thérèse Di Paolo   +10 more
wiley   +1 more source