Results 51 to 60 of about 6,060 (200)

Extraneural Prion Neuroinvasion without Lymphoreticular System Infection [PDF]

, 2005
While prion infection of the lymphoreticular system (LRS) is necessary for neuroinvasion in many prion diseases, in bovine spongiform encephalopathy and atypical cases of sheep scrapie there is evidence to challenge that LRS infection is required for ...
Tucker, Tammy, Bartz, Jason C., Kincaid, Anthony E., Bessen, Richard A., DeJoia, Crista   +4 more
core  

Unhampered prion neuroinvasion despite impaired fast axonal transport in transgenic mice overexpressing four-repeat tau. [PDF]

, 2002
Transmissible spongiform encephalopathies often are caused by peripheral uptake of infectious prions, and the peripheral nervous system is involved in prion spread to the brain.
Markus Glatzel, Künzi, V, Glatzel, M, Valérie Künzi, Michel Y. Nakano, Van Leuven, F, Adriano Aguzzi, Nakano, M Y, Urs F. Greber, Greber, U F, Fred Van Leuven, Aguzzi, A; https://orcid.org/   +11 more
core   +2 more sources

Multiple Sclerosis and Viruses: « Liaisons Dangereuses »

Reviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Samanta Plavina, Daniela Malakovska, Jolanta Kalnina, Ilva Trapina, Elina Leonova, Mohammed Habib, Susanne Schifmann, Jegors Paramonovs, Nikolajs Sjakste, Yegor Vassetzky, Emmanuel Drouet, Natalia Paramonova   +11 more
wiley   +1 more source

List of WNV neuroinvasion-associated amino acid residues in HLA-DRB1 and their properties [25].

, 2018
List of WNV neuroinvasion-associated amino acid residues in HLA-DRB1 and their properties [25].
Agoritsa Baka (217951), Anna Papa (318166), Christos Hadjichristodoulou (33082), Constantina A. Sarri (3330990), Athanasios Tsakris (710808), Charalambos Billinis (412743), Zissis Mamuris (412744), Constantina Politis (3330993), Georgios E. Papadopoulos (782435), Danai Pervanidou (560854)   +9 more
core   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, Volume 36, Issue 6, November 2026.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Beyond the Microbial Hypothesis: Shared Genetic, Osteoimmune and Vascular Mechanisms in the Oral–Brain Axis Linking Periodontitis and Alzheimer's Disease

European Journal of Neuroscience, Volume 64, Issue 9, November 2026.
Periodontitis is linked to Alzheimer's disease (AD) beyond the microbial hypothesis. This review reframes the oral–brain axis as an osteoimmune and vascular problem: The OPG/RANKL system acts as a bone–brain interface in which elevated OPG may limit neuroprotective RANKL, and circulating endocan provides a shared, treatment‐responsive vascular ...
Salma Kabbashi, Mai Ahmed, Manogari Chetty   +2 more
wiley   +1 more source

Progressive cognitive impairment after recovery from neuroinvasive and non-neuroinvasive Listeria monocytogenes infection

Frontiers in Immunology, 2023
BackgroundNeuro-cognitive impairment is a deleterious complication of bacterial infections that is difficult to treat or prevent. Listeria monocytogenes (Lm) is a neuroinvasive bacterial pathogen and commonly used model organism for studying immune responses to infection. Antibiotic-treated mice that survive systemic Lm infection have increased numbers
Benjamin R. Cassidy, Sreemathi Logan, Julie A. Farley, Daniel B. Owen, William E. Sonntag, Douglas A. Drevets   +5 more
openaire   +3 more sources

Severe Pediatric MOGAD‐Associated ADEM With Persistent Neurological Morbidity and Later‐Onset Epilepsy of Uncertain Etiology: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This report describes a 7‐year‐old boy with MOGAD presenting as severe ADEM with fever, encephalopathy, seizures, markedly elevated intracranial pressure, diffuse multifocal MRI abnormalities, and serum MOG‐IgG positivity. He required intravenous corticosteroids, plasma exchange, IVIG, and tocilizumab, followed by rehabilitation and ...
Desiree‐Anne Ramsaran, Garrett Gianneschi, Janet Elgallab   +2 more
wiley   +1 more source

Routes of prion neuroinvasion after peripheral exposure.

, 2013
(a) Natural prion diseases are often acquired via peripheral exposure such as orally, or through skin lesions. How prion reaches its peripheral targets is not known.
Jean-Yves Cesbron (4509), Philippe Naquet (112079), Jean Gagnon (361205), Marie-France Cesbron-Delauw (361204), Catherine Lemaire-Vieille (361203), Corinne Loeuillet (272489)   +5 more
core   +1 more source

The pathogenesis and virulence of enterovirus-D68 infection

Virulence, 2021
In 2014, enterovirus D68 (EV-D68) emerged causing outbreaks of severe respiratory disease in children worldwide. In a subset of patients, EV-D68 infection was associated with the development of central nervous system (CNS) complications, including acute ...
Syriam Sooksawasdi Na Ayudhya, Brigitta M. Laksono, Debby van Riel   +2 more
doaj   +1 more source