Results 11 to 20 of about 349,501 (328)

Myo-Inositol Levels in the Dorsal Hippocampus Serve as Glial Prognostic Marker of Mild Cognitive Impairment in Mice

Frontiers in Aging Neuroscience, 2021
Dementia is a devastating age-related disorder. Its therapy would largely benefit from the identification of susceptible subjects at early, prodromal stages of the disease. To search for such prognostic markers of cognitive impairment, we studied spatial
Tim Ebert, Tim Ebert, Daniel E. Heinz, Daniel E. Heinz, Suellen Almeida-Corrêa, Renata Cruz, Frederik Dethloff, Tibor Stark, Tibor Stark, Tibor Stark, Thomas Bajaj, Oriana M. Maurel, Fabiola M. Ribeiro, Silvio Calcagnini, Kathrin Hafner, Nils C. Gassen, Nils C. Gassen, Christoph W. Turck, Benoit Boulat, Michael Czisch, Carsten T. Wotjak, Carsten T. Wotjak   +21 more
doaj   +1 more source

A simplified microwave-based motion detector for home cage activity monitoring in mice

Journal of Biological Engineering, 2017
Background Locomotor activity of rodents is an important readout to assess well-being and physical health, and is pivotal for behavioral phenotyping.
Andreas Genewsky, Daniel E. Heinz, Paul M. Kaplick, Kasyoka Kilonzo, Carsten T. Wotjak   +4 more
doaj   +1 more source

Reduced neurosteroid potentiation of GABAA receptors in epilepsy and depolarized hippocampal neurons [PDF]

, 2020
OBJECTIVE: Neurosteroids regulate neuronal excitability by potentiating γ-aminobutyric acid type-A receptors (GABARs). In animal models of temporal lobe epilepsy, the neurosteroid sensitivity of GABARs is diminished and GABAR subunit composition is ...
Jansen, Laura A, Joshi, Suchitra, Kapur, Jaideep, Roden, William H   +3 more
core   +2 more sources

S‐nitrosation and neuronal plasticity [PDF]

British Journal of Pharmacology, 2014
Nitric oxide (NO) has long been recognized as a multifaceted participant in brain physiology. Despite the knowledge that was gathered over many years regarding the contribution of NO to neuronal plasticity, for example the ability of the brain to change in response to new stimuli, only in recent years have we begun to understand how NO acts on the ...
Santos, Ana Isabel, Martinez-Ruiz, A., Araújo, Inês   +2 more
openaire   +4 more sources

A longitudinal, randomized experimental pilot study to investigate the effects of airborne ultrasound on human mental health, cognition, and brain structure

Scientific Reports, 2021
Ultrasound-(US) emitting sources are highly present in modern human environments (e.g., movement sensors, electric transformers). US affecting humans or even posing a health hazard remains understudied. Hence, ultrasonic (22.4 kHz) vs.
L. Ascone, C. Kling, J. Wieczorek, C. Koch, S. Kühn   +4 more
doaj   +1 more source

Differences in hippocampal plasticity and memory outcomes in anterior versus posterior cerebellar stroke

Neurobiology of Disease, 2022
Neurological symptoms following cerebellar stroke can range from motor to cognitive-affective impairments. Topographic imaging studies from patients with lesions confined to the cerebellum have shown evidence linking anterior cerebellar lobules with ...
Myriam Moreno, Crystal Minjarez, Jose Vigil, James E. Orfila, Roxanna Schmidt, Amelia Burch, Danelle J. Carter, Molly Kubesh, Joan Yonchek, Robert M. Dietz, Nidia Quillinan   +10 more
doaj   +1 more source

Temporal Map Formation in the Barn Owl’s Brain [PDF]

, 2001
Barn owls provide an experimentally well-specified example of a temporal map, a neuronal representation of the outside world in the brain by means of time. Their laminar nucleus exhibits a place code of interaural time differences, a cue which is used to
Hemmen, Jan Leo van, Kempter, Richard, Leibold, Christian   +2 more
core   +1 more source

A longitudinal, randomized experimental pilot study to investigate the effects of airborne infrasound on human mental health, cognition, and brain structure

Scientific Reports, 2021
Airborne infrasound (IS; emitted by e.g., large machinery, wind farms) is ubiquitous in technologized environments. Health hazards are controversially discussed at present.
L. Ascone, C. Kling, J. Wieczorek, C. Koch, S. Kühn   +4 more
doaj   +1 more source

Why do mice squeak? Toward a better understanding of defensive vocalization

iScience, 2022
Summary: Although mice mostly communicate in the ultrasonic range, they also emit audible calls. We demonstrate that mice selectively bred for high anxiety-related behavior (HAB) have a high disposition for emitting sonic calls when caught by the tail ...
Julia Ruat, Andreas J. Genewsky, Daniel E. Heinz, Sebastian F. Kaltwasser, Newton S. Canteras, Michael Czisch, Alon Chen, Carsten T. Wotjak   +7 more
doaj   +1 more source

Retrograde semaphorin-plexin signalling drives homeostatic synaptic plasticity. [PDF]

, 2017
Homeostatic signalling systems ensure stable but flexible neural activity and animal behaviour. Presynaptic homeostatic plasticity is a conserved form of neuronal homeostatic signalling that is observed in organisms ranging from Drosophila to human ...
A Mahr, A Sahay, AL Franciscovich, AL Kolodkin, Brian O. Orr, CA Frank, CA Frank, DS Syed, E Koropouli, E Marder, F Bouzioukh, G Turrigiano, Graeme W. Davis, GW Davis, HJ Bellen, J de Wit, JC Ayoob, JR Terman, KJT Venken, M Müller, MA Gaviño, MA Younger, MB Ramocki, N Harris, N Uesaka, R-J Hung, R-J Hung, RA Carrillo, Richard D. Fetter, RJ Hung, S Meltzer, SA Petersen, SG Cull-Candy, T Wang, T Wang, TS Tran, Y Luo, Z Wu   +37 more
core   +1 more source