Results 51 to 60 of about 1,018,658 (375)

Alterations in brain connectivity due to plasticity and synaptic delay

open access: yes, 2017
Brain plasticity refers to brain's ability to change neuronal connections, as a result of environmental stimuli, new experiences, or damage. In this work, we study the effects of the synaptic delay on both the coupling strengths and synchronisation in a ...
Batista, A. M.   +8 more
core   +1 more source

Neuronal avalanches of a self-organized neural network with active-neuron-dominant structure [PDF]

open access: yes, 2012
Neuronal avalanche is a spontaneous neuronal activity which obeys a power-law distribution of population event sizes with an exponent of -3/2. It has been observed in the superficial layers of cortex both \emph{in vivo} and \emph{in vitro}. In this paper
Beggs J.   +3 more
core   +2 more sources

Fractal analyses of networks of integrate-and-fire stochastic spiking neurons

open access: yes, 2018
Although there is increasing evidence of criticality in the brain, the processes that guide neuronal networks to reach or maintain criticality remain unclear.
Amon, Mary Jean   +3 more
core   +1 more source

A geographically distributed bio-hybrid neural network with memristive plasticity [PDF]

open access: yes, 2017
Throughout evolution the brain has mastered the art of processing real-world inputs through networks of interlinked spiking neurons. Synapses have emerged as key elements that, owing to their plasticity, are merging neuron-to-neuron signalling with ...
Corna, Andrea   +10 more
core   +1 more source

Reactive oxygen species regulate activity-dependent neuronal plasticity in Drosophila

open access: yeseLife, 2018
Reactive oxygen species (ROS) have been extensively studied as damaging agents associated with ageing and neurodegenerative conditions. Their role in the nervous system under non-pathological conditions has remained poorly understood.
Matthew C. W. Oswald   +9 more
semanticscholar   +1 more source

Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux

open access: yesAntioxidants, 2020
Microglia controls the immune system response in the brain. Specifically, the activation and dysregulation of the NLRP3 inflammasome is responsible for the initiation of the inflammatory process through IL-1β and IL-18 release.
Víctor Farré-Alins   +13 more
doaj   +1 more source

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Protects Striatal Cells and Improves Motor Function in Huntington’s Disease Models: Role of PAC1 Receptor

open access: yesFrontiers in Pharmacology, 2022
Huntington’s disease (HD) is a hereditary neurodegenerative disorder caused by the expression of mutant huntingtin (mHtt). One of the main features of HD is the degeneration of the striatum that leads to motor discoordination. Pituitary adenylate cyclase-
Irene Solés-Tarrés   +11 more
doaj   +1 more source

Neuronal plasticity and neurotrophic factors in drug responses

open access: yesMolecular Psychiatry, 2017
Neurotrophic factors, particularly brain-derived neurotrophic factor (BDNF) and other members of the neurotrophin family, are central mediators of the activity-dependent plasticity through which environmental experiences, such as sensory information are ...
E. Castrén, H. Antila
semanticscholar   +1 more source

Critical neural networks with short and long term plasticity

open access: yes, 2017
In recent years self organised critical neuronal models have provided insights regarding the origin of the experimentally observed avalanching behaviour of neuronal systems.
de Arcangelis, L.   +3 more
core   +2 more sources

THE FUNDAMENTS OF NEURONAL PLASTICITY

open access: yesAnnals of the Russian academy of medical sciences, 2012
 Plasticity of the nervous system  is determined by the modification of efficacy of synaptic transmission: long- term potentiation and long- term depression. Different modern technical approaches such as: registration of ionic currents in single neuron, molecular- genetic analysis, neurovisualization, and others reveal the molecular mechanisms of ...
M. B. Shtark, V. G. Skrebitskii
openaire   +3 more sources

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