Results 71 to 80 of about 191,422 (338)

Development and Validation of a One‐Dimensional Finite Difference Simulation Scheme for Polymer Laser Powder Bed Fusion with Application to the Effect of the Inter Layer Time

open access: yesAdvanced Engineering Materials, EarlyView.
The study presents an efficient simulation approach for the polymer laser powder bed fusion process polymers process, validated with polyamide 12, polyamide 6, and polyetherketoneketone. It shows that inter layer time affects part density, with 90s yielding dense parts.
Claas Bierwisch   +4 more
wiley   +1 more source

Why do mice squeak? Toward a better understanding of defensive vocalization

open access: yesiScience, 2022
Summary: Although mice mostly communicate in the ultrasonic range, they also emit audible calls. We demonstrate that mice selectively bred for high anxiety-related behavior (HAB) have a high disposition for emitting sonic calls when caught by the tail ...
Julia Ruat   +7 more
doaj  

A Case‐Based Reasoning Approach to Model Manufacturing Constraints for Impact Extrusion

open access: yesAdvanced Engineering Materials, EarlyView.
A hybrid modeling approach is presented that combines constraint‐based process modeling and case‐based reasoning. The model formalizes manufacturing constraints and integrates simulation data to model complex manufacturing processes. The approach supports manufacturability analysis during product design through an adaptive modeling environment.
Kevin Herrmann   +5 more
wiley   +1 more source

Static and Dynamic Behavior of Novel Y‐Shaped Sandwich Beams Subjected to Compressive Loadings: Integration of Supervised Learning and Experimentation

open access: yesAdvanced Engineering Materials, EarlyView.
In this study, the mechanical response of Y‐shaped core sandwich beams under compressive loading is investigated, using deep feed‐forward neural networks (DFNNs) for predictive modeling. The DFNN model accurately captures stress–strain behavior, influenced by design parameters and loading rates.
Ali Khalvandi   +4 more
wiley   +1 more source

Physiological and pathophysiological control of synaptic GluN2B-NMDA receptors by the C-terminal domain of amyloid precursor protein

open access: yeseLife, 2017
The amyloid precursor protein (APP) harbors physiological roles at synapses and is central to Alzheimer’s disease (AD) pathogenesis. Evidence suggests that APP intracellular domain (AICD) could regulate synapse function, but the underlying molecular ...
Paula A Pousinha   +11 more
doaj   +1 more source

Functional Restoration following Global Cerebral Ischemia in Juvenile Mice following Inhibition of Transient Receptor Potential M2 (TRPM2) Ion Channels

open access: yesNeural Plasticity, 2021
Hippocampal cell death and cognitive dysfunction are common following global cerebral ischemia across all ages, including children. Most research has focused on preventing neuronal death.
Robert M. Dietz   +7 more
doaj   +1 more source

Multimaterial Approach to Improve the Mechanical Properties of a Novel Modified Auxetic Reentrant Honeycomb Structure

open access: yesAdvanced Engineering Materials, EarlyView.
A multimaterial approach is introduced to improve upon auxetic structures by combining two different polymers into the same reentrant honeycomb structure via additive manufacturing. The deformation behavior as well as the resulting Poisson's ratio are thereby improved significantly.
Alexander Engel   +2 more
wiley   +1 more source

Cell Type-specific Metabolic Labeling of Proteins with Azidonorleucine in Drosophila

open access: yesBio-Protocol, 2017
Advanced mass spectrometry technology has pushed proteomic analyses to the forefront of biological and biomedical research. Limitations of proteomic approaches now often remain with sample preparations rather than with the sensitivity of protein ...
Ines Erdmann   +9 more
doaj   +1 more source

Biomimetic Design of Biocompatible Neural Probes for Deep Brain Signal Monitoring and Stimulation: Super Static Interface for Immune Response‐Enhanced Contact

open access: yesAdvanced Functional Materials, EarlyView.
Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong   +7 more
wiley   +1 more source

Strategies for the Identification of Bioactive Neuropeptides in Vertebrates

open access: yesFrontiers in Neuroscience, 2019
Neuropeptides exert essential functions in animal physiology by controlling e.g., reproduction, development, growth, energy homeostasis, cardiovascular activity and stress response.
Auriane Corbière   +10 more
doaj   +1 more source

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