Results 101 to 110 of about 12,871 (217)

Sex Differences in the Anticonvulsant Activity of Neurosteroids

Journal of Neuroscience Research, 2017
Epilepsy is one of the leading causes of chronic neurological morbidity worldwide. Acquired epilepsy may result from a number of conditions, such as brain injury, anoxia, tumors, stroke, neurotoxicity, and prolonged seizures.
Doodipala Samba Reddy
semanticscholar   +1 more source

Neurosteroids [PDF]

The Journal of Physiology, 1999
Willy Mayo, Monique Vallée, Muriel Darnaudéry, Michel Le Moal   +3 more
  +4 more sources

Regulation of neurosteroid biosynthesis by neurotransmitters and neuropeptides

Frontiers in Endocrinology, 2012
The enzymatic pathways leading to the synthesis of bioactive steroids in the brain are now almost completely elucidated in various groups of vertebrates and, during the last decade, the neuronal mechanisms involved in the regulation of neurosteroid ...
Jean-Luc eDo-Rego, Jae Young eSeong, Delphine eBurel, Jérôme eLEPRINCE, David eVaudry, David eVaudry, Van eLuu-The, Marie-Christine eTonon, Marie-Christine eTonon, Kazuyoshi eTsutsui, Georges ePelletier, Hubert eVaudry, Hubert eVaudry   +12 more
doaj   +1 more source

Exploring the connection between several neurosteroid hormones and first-episode psychosis and schizophrenia: A literature review

Annales Academiae Medicae Silesiensis
First-episode psychosis (FEP) and first-episode schizophrenia (FES) are serious psychiatric conditions. Neurosteroids, known to modulate central nervous system function, may play a role in the pathophysiology of these disorders.
Alicja Gładysz, Alicja Dydyna, Martyna Mościcka, Marta Gierlik   +3 more
doaj   +1 more source

Neurosteroids and GABA-A Receptor Function [PDF]

Frontiers in Endocrinology, 2011
Neurosteroids represent a class of endogenous steroids that are synthesized in the brain, the adrenals, and the gonads and have potent and selective effects on the GABAA-receptor. 3α-hydroxy A-ring reduced metabolites of progesterone, deoxycorticosterone, and testosterone are positive modulators of GABA(A)-receptor in a non-genomic manner ...
openaire   +3 more sources

Neurosteroids Induce Allosteric Effects on the NMDA Receptor : Nanomolar Concentrations of Neurosteroids Exert Non-Genomic Effects on the NMDA Receptor Complex

, 2008
The neurosteroids constitute a group of powerful hormones synthesized and acting in the central nervous system. They participate in a number of important central processes, such as memory and learning, mood and neuroprotection.
Johansson, Tobias
core   +2 more sources

Neuroprotectant Properties of Neurosteroids During Neonatal Ethanol Exposure

, 2010
Neonatal ethanol exposure significantly affected development of medial prefrontal cortex pyramidal neurons by decreasing apical dendritic length and intersections.
Yates, Christine
core   +1 more source

Glia-neuron interactions: neurosteroids.

, 2010
Glial cells have both beneficial and detrimentaleffects on recovery from brain damage and playa role in epileptogenesis. Herein, we summarizeevidence indicating that the ability of astrocytesto produce neurosteroids that reinforce c-aminobutyricacid ...
Massimo Avoli, BIAGINI, Giuseppe, Giuseppe Biagini, M. Avoli   +3 more
core   +1 more source

Insights into neurosteroids and their role in women with epilepsy

Frontiers in Global Women's Health
Epilepsy, is a serious neurological condition, characterized by recurring, unprovoked seizures and affects over 50 million people worldwide. Epilepsy has an equal prevalence in males and females, and occurs throughout the life span.
Lata Vadlamudi, Lata Vadlamudi, Daniel Paul Ashley, Daniel Paul Ashley, P. Emanuela Voinescu   +4 more
doaj   +1 more source

Epilepsy and Sex Hormones

Archives of Epilepsy, 2018
There is a mutual interaction between sex steroid hormones and epilepsy. Although female and male sex hormones and their metabolites access the brain via the blood brain barrier, they can also be synthesized de novo from cholesterol within the glia and ...
Emine GENÇ, Bülent Oğuz GENÇ
doaj   +1 more source