Results 81 to 90 of about 12,871 (217)
Epilepsy is often treated with a combination of antiepileptic drugs. Although neurosteroids are potent anticonvulsants, little is known about their combination potential for the treatment of refractory epilepsy.
Shu-Hui Chuang, D. Reddy
semanticscholar +1 more source
Graphical summary of the effects of additional intake of animal and plant proteins on anthropometric and body composition parameters in pre‐ and postmenopausal women. The arrows indicate an increase, decrease, or no significant effect. ABSTRACT This systematic review investigated the effect of protein intake on anthropometric and body composition ...
Sthéfany Nonato Fialho +4 more
wiley +1 more source
Holistic management of epilepsy in adults with intellectual development disorders
Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca +10 more
wiley +1 more source
Clinical Potential of Neurosteroids for CNS Disorders
Summary Neurosteroids are key endogenous molecules in the brain that affect many neural functions. Here, we describe recent advances in NIH-sponsored and other clinical studies of neurosteroids for CNS disorders.
D. Reddy, William A Estes
semanticscholar +1 more source
Myxomatous mitral valve disease, an acquired valvular degeneration, is the most common cardiac disorder in dogs, affecting approximately 10% of dogs in primary care veterinary practice. Dogs with myxomatous mitral valve disease frequently require anaesthesia for routine procedures.
I. Levinzon +3 more
wiley +1 more source
Calcium-engaged Mechanisms of Nongenomic Action of Neurosteroids
Background: Neurosteroids form the unique group because of their dual mechanism of action. Classically, they bind to specific intracellular and/or nuclear receptors, and next modify genes transcription.
Zylinska, Ludmila +3 more
core +1 more source
Steroids synthesized de novo by the central and peripheral nervous systems are called neurosteroids. The formation of neurosteroids from cholesterol in the brain was originally demonstrated in mammals by Baulieu and colleagues.
Kazuyoshi eTsutsui +5 more
doaj +1 more source
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin +3 more
wiley +1 more source
Neurosteroids for a successful pregnancy
Steroid hormones play a critical role in the initiation and maintenance of pregnancy. In particular, the important role that the progesterone metabolite, and neurosteroid, allopregnanolone, may play in fetal and adolescent development is becoming increasingly evident.
Cheryl A, Frye +3 more
openaire +2 more sources
Neurosteroids as Endogenous Modulators of Epileptic Seizures
Neurosteroids are a family of steroidal compounds which produce a variety of biological effects, mainly by interacting with the γ-aminobutyric acid receptor A (GABAA).
Giuseppe Biagini +3 more
core +1 more source

