Results 11 to 20 of about 14,599 (210)

The Anti-Apoptotic Role of Neurotensin

open access: yesCells, 2013
The neuropeptide, neurotensin, exerts numerous biological functions, including an efficient anti-apoptotic role, both in the central nervous system and in the periphery.
Jean Mazella   +3 more
doaj   +2 more sources

Decreased neurotensin levels as a biomarker in resistant hypertension

open access: yesClinical and Experimental Hypertension, 2020
Objective: Although neurotensin is found throughout the body including cardiovascular structures, the correlation of plasma neurotensin levels with resistant hypertension (RH) has never been examined.
Ismail Bolat   +4 more
doaj   +2 more sources

The hindbrain-hypothalamic noradrenergic pathway controls homeostatic food intake but not cue-induced appetitive behaviors. [PDF]

open access: yesJ Neuroendocrinol
Abstract Nucleus of the solitary tract (NTS) A2 noradrenergic neurons are critical in regulating food intake. In addition to their well‐established role in homeostatic feeding, there is also evidence indicating their contribution in non‐homeostatic feeding behaviors. However, whether their control of homeostatic and non‐homeostatic feeding behaviors is
Vuong C, Yap JA, Gu HYS, Lai HY, Ong ZY.
europepmc   +2 more sources

Neurotensin and Xenin Show Positive Correlations With Perceived Stress, Anxiety, Depressiveness and Eating Disorder Symptoms in Female Obese Patients

open access: yesFrontiers in Behavioral Neuroscience, 2021
ObjectiveNeurotensin and xenin are two closely related anorexigenic neuropeptides synthesized in the small intestine that exert diverse peripheral and central functions. Both act via the neurotensin-1-receptor. In animal models of obesity reduced central
Ellen Wölk   +5 more
doaj   +1 more source

Regulation of fat-stimulated neurotensin secretion in healthy subjects [PDF]

open access: yes, 2008
CONTEXT: Cholecystokinin (CCK) and neurotensin are stimulated during meal intake by the presence of fat in the small intestine. The sequence of events suggests that fat hydrolysis is crucial for triggering the release.
Drewe, J.   +3 more
core   +1 more source

Neurotensin receptors in GtoPdb v.2023.1 [PDF]

open access: yes, 2023
Neurotensin receptors (nomenclature as recommended by NC-IUPHAR [39]) are activated by the endogenous tridecapeptide neurotensin (pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu) derived from a precursor (NTS, 30990), which also generates neuromedin
Philippe Sarret   +5 more
core   +1 more source

Increased adipose tissue lymphatic vessel density inhibits thermogenesis through elevated neurotensin levels

open access: yesFrontiers in Cell and Developmental Biology, 2023
During cold exposure, white adipose tissue can remodel to dissipate energy as heat under cold similar to thermogenic brown adipose tissue. This “browning” and the regulation of body temperature is under the control of neural and hormonal signaling.
Thien T. Phan   +6 more
doaj   +1 more source

Heterodimerization of apelin receptor and neurotensin receptor 1 induces phosphorylation of ERK1/2and cell proliferationviaGαq-mediated mechanism [PDF]

open access: yes, 2014
Dimerization of G protein-coupled receptors (GPCRs) is crucial for receptor function including agonist affinity, efficacy, trafficking and specificity of signal transduction, including G protein coupling.
Cai, X   +9 more
core   +1 more source

Neurotensin receptors in pancreatic ductal carcinomas. [PDF]

open access: yes, 2015
BACKGROUND The frequent expression of neurotensin receptors (NT-R) in primaries of pancreatic ductal carcinomas has triggered the development of radioactive neurotensin analogs for possible in vivo targeting of these tumors. However, the complete lack
Strobel, Oliver   +9 more
core   +2 more sources

Preparation and Preliminary Evaluation of Neurotensin Radiolabelled with 68Ga and 177Lu as Potential Theranostic Agent for Colon Cancer

open access: yesPharmaceutics, 2021
The neurotensin is a tridecapeptide involved in the proliferation of colon cancer, the overexpression of neurotensin receptors occurring at an early stage development of many tumours.
Radu Anton Leonte   +6 more
doaj   +1 more source

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