Results 21 to 30 of about 14,599 (210)

Spinal relay neurons for central control of autonomic pathways in a photoperiodic rodent [PDF]

open access: yesJournal of Integrative Neuroscience, 2021
Location and distribution of spinal sympathetic preganglionic neurons projecting to the superior cervical ganglion were investigated in a rodent model organism for photoperiodic regulation, the Djungarian hamster (Phodopus sungorus).
Stefan Reuss
doaj   +1 more source

Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells

open access: yesBMC Cancer, 2011
Background Neurotensin has been found to promote colon carcinogenesis in rats and mice, and proliferation of human colon carcinoma cell lines, but the mechanisms involved are not clear.
Dajani Olav   +7 more
doaj   +1 more source

Neurotensin: A role in substance use disorder? [PDF]

open access: yes, 2016
Neurotensin is a tridecapeptide originally identified in extracts of bovine hypothalamus. This peptide has a close anatomical and functional relationship with the mesocorticolimbic and nigrostriatal dopamine system. Neural circuits containing neurotensin
Ferraro, Luca   +16 more
core   +2 more sources

Targeting neurotensin as a potential novel approach for the treatment of autism

open access: yesJournal of Neuroinflammation, 2010
The pathophysiology of autism remains obscure. Recently, serum neurotensin levels in children with autistic disorder have been found to be higher than those of normal children. Neurotensin is known to intensify neuronal NMDA-mediated glutamate signaling,
Ghanizadeh Ahmad
doaj   +1 more source

The role of Neurotensin and its receptors in non-gastrointestinal cancers: a review

open access: yesCell Communication and Signaling, 2020
Background Neurotensin, originally isolated in 1973 has both endocrine and neuromodulator activity and acts through its three main receptors. Their role in promoting tumour cell proliferation, migration, DNA synthesis has been studied in a wide range of ...
Stella Nikolaou   +6 more
doaj   +1 more source

Dissecting the Roles of GABA and Neuropeptides from Rat Central Amygdala CRF Neurons in Anxiety and Fear Learning

open access: yesCell Reports, 2019
Summary: Central amygdala (CeA) neurons that produce corticotropin-releasing factor (CRF) regulate anxiety and fear learning. These CeACRF neurons release GABA and several neuropeptides predicted to play important yet opposing roles in these behaviors ...
Matthew B. Pomrenze   +5 more
doaj   +1 more source

Plasma neuropeptide levels in patients with schizophrenia, bipolar disorder, or major depressive disorder and healthy controls: A multiplex immunoassay study

open access: yesNeuropsychopharmacology Reports, 2023
Aim We aimed to compare neuropeptide levels between patients with major psychiatric disorders and healthy controls and examine their association with symptoms and cognitive function.
Shinsuke Hidese   +5 more
doaj   +1 more source

Probing the environment of neurotensin whilst bound to the neurotensin receptor by solid state NMR [PDF]

open access: yes, 2002
A functionally active analogue of neurotensin, neurotensin(8–13), has been observed whilst bound to the agonist-binding site of the rat neurotensin receptor by nuclear magnetic resonance (NMR).
S. Bains   +15 more
core   +1 more source

CB1 cannabinoid receptors are involved in neuroleptic-induced enhancement of brain neurotensin [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2014
Objective(s): Targeting the neuropeptide systems has been shown to be useful for the development of more effective antipsychotic drugs. Neurotensin, an endogenous neuropeptide, appears to be involved in the mechanism of action of antipsychotics. However,
Parichehr Hassanzadeh, Fatemeh Rostami
doaj  

A Marine Analgesic Peptide, Contulakin-G, and Neurotensin are Distinct Agonists for Neurotensin Receptors: Uncovering Structural Determinants of Desensitization Properties

open access: yesFrontiers in Pharmacology, 2015
Neurotensin receptors have been studied as molecular targets for the treatment of pain, schizophrenia, addiction, or cancer. Neurotensin (NT) and Contulakin-G, a glycopeptide isolated from a predatory cone snail Conus geographus, share a sequence ...
Hee-Kyoung eLee   +10 more
doaj   +1 more source

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