Results 251 to 260 of about 291,313 (279)
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Neurotransmitter Release

1999
Abstract Understanding the mechanisms that underlie brain activity and function remains one of the major frontiers of biology. All the processes of how we co-ordinate our movements, sense our surroundings, react to stimuli and learn and retain information rely on complicated networks of neurons that communicate with each other and their ...
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Talking back: dendritic neurotransmitter release

Trends in Neurosciences, 2003
Classical transmitters and neuropeptides can be released from the dendrites of many neuronal populations, to act as retrograde signals that modulate synaptic transmission, electrical activity and, in some cases, morphology of the cell of origin. For the hypothalamic neuroendocrine cells that release vasopressin and oxytocin, the stimuli, mechanisms and
Mike, Ludwig, Quentin J, Pittman
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Carrier-mediated release of neurotransmitters

Trends in Neurosciences, 1993
There is growing evidence that neurotransmitters can be released not only by exocytosis but also through the membrane carriers responsible for transmitter reuptake. Giulio Levi and Maurizio Raiteri review the in vitro and in vivo evidence supporting the existence of a carrier-mediated release for different classes of transmitters.
G, Levi, M, Raiteri
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Calcium Sensors of Neurotransmitter Release

2023
Calcium (Ca2+) plays a critical role in triggering all three primary modes of neurotransmitter release (synchronous, asynchronous, and spontaneous). Synaptotagmin1, a protein with two C2 domains, is the first isoform of the synaptotagmin family that was identified and demonstrated as the primary Ca2+ sensor for synchronous neurotransmitter release ...
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Neurotransmitter Release

2017
The biochemical and physiological processes of neurotransmitter release from an active zone, a specialized region of synaptic membrane, are examined. Synaptic vesicles containing neurotransmitters are docked at the active zone and then primed for release by SNARE complexes that bring them into extreme proximity to the plasma membrane.
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Molecular mechanisms in neurotransmitter release

Current Opinion in Neurobiology, 1991
The vesicle hypothesis of neurotransmitter release was first formulated in the 1950s, but only recently have the molecular mechanisms involved in neurotransmitter release begun to be elucidated. This short review summarizes current concepts on neurosecretion and the available information on synaptic vesicle exocytosis.
M. Matteoli, P. De Camilli
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Molecular mechanisms of neurotransmitter release

Muscle & Nerve, 2001
AbstractThe release of neurotransmitter from neurons represents one of the pivotal events in synaptic transmission. Neurotransmitters are released from synaptic vesicles in presynaptic neurons in response to neural activity, diffuse across the synaptic cleft, and bind specific receptors in order to bring about changes in postsynaptic neurons.
E A, Fon, R H, Edwards
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The bioenergetics of neurotransmitter release

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1991
Synaptosomal energetics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 245 A. Na + and K+-circuits across the synaptosomal plasma membrane . . . . . . . . . . . . . . . . . . . . . 246 B. The thermodynamics of Na + coupled transmitter carriers . . . . . . . . . . . . . . . . . . . . . . . . . 248
H T, McMahon, D G, Nicholls
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Storage and release of neurotransmitters

Cell, 1993
Because synaptic vesicles and secretory granules are simple in composition and easy to purify, many of their protein components have been identified and often sequenced. Attempts are underway to link the small number of membrane proteins to the small number of functions the vesicles perform.
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Neurotransmitter release at fast synapses

The Journal of Membrane Biology, 1994
As stated at the beginning of this review, the mechanism of neurotransmitter release is not yet known. Keeping this in mind, we shall, nevertheless, attempt to speculate and outline a possible scenario of events as it emerges from the foregoing discussion.
H, Parnas, I, Parnas
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