Results 231 to 240 of about 292,316 (294)

o‐Terphenyl‐Based Family of Conjugated Macrocycles: Selective Recognition of Phenylalanine in Water and Interaction With Insulin

Angewandte Chemie International Edition, EarlyView.
This study presents the synthesis and binding properties of a new family of o‐terphenyl‐based macrocycles, TP[n] (n = 2‐8). The trimer variant efficiently binds phenylalanine in water with a 10‐fold selectivity compared to other amino acids and aromatic neurotransmitters.
Swapnil Ghule, Sayan Sarkar, Maria Eugenia Pérez‐Ojeda Rodriguez, Mark Spector, Frank Hampel, Evgeny A. Kataev   +5 more
wiley   +1 more source

Erratum: Schlüter et al., "Rabphilin Knock-Out Mice Reveal That Rabphilin Is Not Required for Rab3 Function in Regulating Neurotransmitter Release". [PDF]

J Neurosci
europepmc   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

The role of auditory sensory input during functional pre- and postsynaptic maturation of the calyx of Held synapse. [PDF]

, 2007
Erazo Fischer, E.
core   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

Nerve growth factor is sufficient to cause multiple osteoarthritis‐relevant pathological features in naïve murine knee joints

Arthritis &Rheumatology, Accepted Article.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped due to side‐effects in the joints. Knowledge about the biological effects of NGF on joint tissues is limited.
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Light-dependent regulation of neurotransmitter release from rod photoreceptor ribbon synapses involves an interplay of Complexin 4 and Transducin with the SNARE complex. [PDF]

Front Mol Neurosci
Lux UT, Meyer J, Jahn O, Davison A, Babai N, Gießl A, Wartenberg A, Sticht H, Brose N, Reim K, Brandstätter JH.   +10 more
europepmc   +1 more source

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Synaptotagmin and neurotransmitter release

Cell, 1993
William M. DeBello,’ Heinrich Bet Torri-Tarelli et al., 1985), and that this exocytosis is trig- gered by a rise in the concentration of Ca within presynap- tic terminals (Miledi, 1973). The source of this triggering Ca is the voltage-gated Ca channel, which is found in close proximity to the sites of exocytosis (Augustine et al., 1987).
W M, DeBello, H, Betz, G J, Augustine
openaire   +4 more sources

Biochemistry of Neurotransmitter Release

Annual Review of Neuroscience, 1979
tcalcium channels transiently. The brief intlux of calcium rapidly stimulates release of quanta of transmitter, which in turn produce postsynaptic change in conductance. Anatomical studies of the morphology of nerve terminals have correlated the quantum of transmitter release with exocyto­ sis of the contents of a single synaptic vesicle.
R B, Kelly, J W, Deutsch, S S, Carlson, J A, Wagner   +3 more
openaire   +2 more sources

Neurotransmitter Release

Annual Review of Neuroscience, 1996
Synaptic vesicle exocytosis is rapid and highly localized, which are features that arise from the organization of the presynaptic active zone, where vesicle fusion occurs. Colocalization of calcium channels with the proteins making up the vesicle docking machinery at the active zone, combined with the low affinity and high cooperativity of the calcium ...
openaire   +2 more sources