Results 61 to 70 of about 1,017,928 (387)
Neutrophil chemoattractant receptors in health and disease: double-edged swords
Cellular & Molecular Immunology, 2020 Neutrophils are frontline cells of the innate immune system. These effector leukocytes are equipped with intriguing antimicrobial machinery and consequently display high cytotoxic potential. Accurate neutrophil recruitment is essential to combat microbes
Mieke Metzemaekers, M. Gouwy, P. Proost
semanticscholar +1 more source
Variations in the Phagosomal Environment of Human Neutrophils and Mononuclear Phagocyte Subsets
Frontiers in Immunology, 2019 The phagosome microenvironment maintains enzyme activity and function. Here we compared the phagosomal pH of human neutrophils, monocytes, dendritic cells (DC), and monocyte-derived cells.
Juliet R. Foote +3 more
doaj +1 more source
Nature Communications, 2020 Gasdermin-D (GSDMD) in inflammasome-activated macrophages is cleaved by caspase-1 to generate N-GSDMD fragments. N-GSDMD then oligomerizes in the plasma membrane (PM) to form pores that increase membrane permeability, leading to pyroptosis and IL-1β ...
Mausita Karmakar +12 more
semanticscholar +1 more source
Nature Immunology, 2014 In this Review we discuss data demonstrating recently recognized aspects of neutrophil homeostasis in the steady state, granulopoiesis in 'emergency' conditions and interactions of neutrophils with the adaptive immune system. We explore in vivo observations of the recruitment of neutrophils from blood to tissues in models of blood-borne infections ...
Nauseef, William M, Borregaard, Niels
openaire +4 more sources
Immunological Reviews, 2023 neutrofili, infiammazione, immunità
Marco A. Cassatella, William M. Nauseef
openaire +3 more sources
Medical Sciences, 2016 The renal functions and structure in sickle cell anaemia (SCA) patients may be affected by chronic haemodynamic changes and consequences of vaso-occlusive events in the renal medulla.
Mathias Abiodun Emokpae +2 more
doaj +1 more source
IL-17 can be protective or deleterious in murine pneumococcal pneumonia [PDF]
, 2018 Streptococcus pneumoniae is the major bacterial cause of community-acquired pneumonia, and the leading agent of childhood pneumonia deaths worldwide. Nasal colonization is an essential step prior to infection.
Bayes, Hannah K. +4 more
core +3 more sources
Conserved Inhibition of Neutrophil Extracellular Trap Release by Clinical Candida albicans Biofilms
Journal of Fungi, 2017 Candida albicans biofilms are difficult to eradicate due to their resistance to host defenses and antifungal drugs. Although neutrophils are the primary responder to C. albicans during invasive candidiasis, biofilms resist killing by neutrophils.
John F. Kernien +2 more
doaj +1 more source
The Emerging Role of Neutrophil Extracellular Traps (NETs) in Tumor Progression and Metastasis
Frontiers in Immunology, 2020 Neutrophil Extracellular Traps (NETs) are net-like structures composed of DNA-histone complexes and proteins released by activated neutrophils. In addition to their key role in the neutrophil innate immune response, NETs are also involved in autoimmune ...
M. Masucci +3 more
semanticscholar +1 more source
The effect of pegbovigrastim on circulating neutrophil count in dairy cattle : a randomized controlled trial [PDF]
, 2018 Previous research in various species has shown that granulocyte-colony stimulating factor stimulates the production and release of neutrophils from bone marrow.
Bogado Pascottini, Osvaldo Américo +3 more
core +1 more source