Results 111 to 120 of about 922,978 (253)

New Paths to Spatial Expression from a Digital Humanities Perspective

open access: yesRedai dili
In the context of the digital age, digital humanities has evolved into a cutting-edge interdisciplinary field that deeply integrates computational and humanistic thinking, representing a fundamental shift in research paradigms driven by data, employing ...
Zhuang Liang, Ye Chao
doaj   +1 more source

Rethinking Leninism [PDF]

open access: yes, 2009
This special section on ‘Rethinking Leninism’ emerges from sessions organized at the Society for Socialist Studies’ Annual Meetings, held at the Congress of the Humanities and Social Sciences in May 2009 at Carleton University in Ottawa, Ontario, Canada.
Levant, Alex
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Incite 2012: Angels and Demons, March 10-12, 2012 [PDF]

open access: yes, 2012
This is the concert program of the Incite 2012: Angels and Demons performance on Saturday, March 10, 2012 at 8:00 p.m., at the BMCC Tribeca Performing Arts Center, 199 Chambers St, New York. New York.
School of Music, Boston University
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Durkheim's imperative: The role of Humanities faculty in the information technologies revolution [PDF]

open access: yes, 1994
The arrival of powerful information technologies in the traditional humanistic disciplines has done far more than simply add to the tools available for research and instruction.
Jones, Robert Alun
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Boston University Glee Club, April 23, 1964 [PDF]

open access: yes, 1964
This is the concert program of the Boston University Glee Club performance on Thursday, April 23, 1964 at 8:30 p.m., at the Concert Hall, 855 Commonwealth Avenue.
School of Music, Boston University
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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