Results 51 to 60 of about 258,608 (128)

SLAMF8 and NINJ2 promote neuroinflammation and oxidative stress through TLR4 NF kappa B pathway in Alzheimer’s disease

open access: yesScientific Reports
This study aimed to investigate the expression and role of Signaling Lymphocytic Activation Molecule Family Member 8 (SLAMF8) in Alzheimer’s disease (AD), particularly its interaction with NINJ2 in the TLR4/NF-κB signaling pathway.
Shuo Liu   +6 more
doaj   +1 more source

NF-κB in biology and targeted therapy: new insights and translational implications

open access: yesSignal Transduction and Targeted Therapy
NF-κB signaling has been discovered for nearly 40 years. Initially, NF-κB signaling was identified as a pivotal pathway in mediating inflammatory responses.
Qing Guo   +8 more
doaj   +1 more source

PCV2 Induced Endothelial Derived IL-8 Affects MoDCs Maturation Mainly via NF-κB Signaling Pathway

open access: yesViruses
Porcine circovirus type 2 (PCV2) infection can cause immunosuppressive diseases in pigs. Vascular endothelial cells (VECs), as the target cells for PCV2, play an important role in the immune response and inflammatory regulation.
Mengyu Zhang   +7 more
doaj   +1 more source

NF‐κB affected the serum levels of TNF‐α and IL‐1β via activation of the MAPK/NF‐κB signaling pathway in rat model of acute pulmonary microthromboembolism

open access: yesPulmonary Circulation
Pulmonary thromboembolism caused by thrombi blocking major pulmonary artery and its branches, is a frequently encountered phenomenon and an important cause of high morbidity and mortality in lung diseases and may develop into persistent pulmonary ...
Yanfen Zhong   +6 more
doaj   +1 more source

The Role of the NF-κB Signaling Pathway in Atherosclerotic Plaque Rupture and Targeted Therapeutic Strategies. [PDF]

open access: yesBiomedicines
Yin L   +9 more
europepmc   +1 more source

Modulation of NF-κB signaling pathway by tocotrienol in neurodegenerative diseases. [PDF]

open access: yesDiscov Ment Health
Ang SY   +5 more
europepmc   +1 more source

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