Results 201 to 210 of about 151,448 (273)

Simvastatin induces heme oxygenase-1 via NF-E2-related factor 2 (Nrf2) activation through ERK and PI3K/Akt pathway in colon cancer. [PDF]

Oncotarget, 2016
Jang HJ, Hong EM, Kim M, Kim JH, Jang J, Park SW, Byun HW, Koh DH, Choi MH, Kae SH, Lee J.   +10 more
europepmc   +1 more source

Network Analysis Identifies Microsomal Glutathione S‐Transferase as a Potential Regulator of Oxidative Stress and Proteasome Dysfunction in Human Osteoarthritic Menisci

FASEB BioAdvances, Volume 8, Issue 5, May 2026.
Schematic diagram of the study design. OA = osteoarthritis, GSE = Genomic Spatial Event database, DEG = Differentially expressed genes, WGCNA = Weighted gene co‐expression network analysis, MCC = Maximal clique centrality. ABSTRACT Osteoarthritis (OA)‐related meniscal degeneration involves complex interactions between oxidative stress and proteasomal ...
Xinjie Wu, Amina Hamzatova, Cecilia Aulin, Wei Sun, Andre Struglics, David A. Hart, Paul W. Ackermann, Aisha S. Ahmed   +7 more
wiley   +1 more source

Methylseleninic acid induces NAD(P)H:quinone oxidoreductase-1 expression through activation of NF-E2-related factor 2 in Chang liver cells. [PDF]

Oncotarget, 2018
Park JM, Kim DH, Na HK, Surh YJ.
europepmc   +1 more source

Preoperative Beta‐Hydroxy‐Beta‐Methyl‐Butyrate Supplementation Reduces Mitochondrial Dynamics Proteins and Preserves Hepatic Mitochondrial Function After Partial Hepatectomy in Mice

Acta Physiologica, Volume 242, Issue 5, May 2026.
ABSTRACT Aim The liver exhibits a remarkable regenerative capacity, enabling this organ to maintain homeostasis even after significant injury. However, hepatic regeneration requires sufficient energy to sustain cellular hypertrophy and proliferation, thus ensuring efficient tissue repair.
A. L. Vieira‐da‐Silva, M. V. Esteca, F. A. Silva, I. A. Divino, F. S. Carneiro, E. R. Ropelle, A. S. Torsoni, I. L. Baptista   +7 more
wiley   +1 more source

Cervical Cancer and the Nuclear Transcription Factor NF-E2-Related Factor 2

Advances in Clinical Medicine
openaire   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, Volume 183, Issue 9, Page 1727-1746, May 2026.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Targeting Inflammation and Immune Regulation in Chronic Inflammation Associated Cancers

Cancer Science, Volume 117, Issue 5, Page 1209-1222, May 2026.
Chronic inflammation sustains activation of key inflammatory pathways, including Nuclear factor kappa B (NF‐κB), Interleukin‐6‐signal transducer and activator of transcription 3 (IL6‐STAT3), Phosphoinositide 3‐kinase/Akt (PI3K/Akt), and Wingless/β‐catenin (Wnt/β‐catenin) signaling. This promotes immune dysregulation through the expansion and functional
Lawan Rabiu, Mengzhu Chinn, Feng Chen, Yerkezhan Yerkinkazhina, Yuan Tian, Wei‐Guo Zhu   +5 more
wiley   +1 more source

Whole Blood Transcriptomic Analysis of Sickle Cell Trait

European Journal of Haematology, Volume 116, Issue 5, Page 535-544, May 2026.
ABSTRACT Sickle cell trait (SCT) is the heterozygous carrier state for the HBB missense variant which causes sickle cell disease (SCD). SCT has been associated with increased risk of venous thromboembolism and chronic kidney disease as well as alterations in clinical laboratory parameters. To investigate differential gene expression in SCT, we used RNA
Mari Johnson, Yanwei Cai, Ana Gabriela Vasconcelos, Peter Orchard, Paul L. Auer, Guillaume Lettre, Jia Wen, Nora Franceschini, Charles Kooperberg, Wei Sun, Li Hsu, Laura M. Raffield, Alex P. Reiner   +12 more
wiley   +1 more source

Why Is MS a More Frequent Complication of EBV Infection in Females?

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Multiple sclerosis (MS) is a T helper (Th) cell‐mediated disease that targets central nervous system (CNS) white matter. This disease affects three times more females than males. For many years, the etiology of MS was not well understood and the exact nature of the autoimmune reaction was speculative.
Shannon E. Dunn, Nuria Alvarez‐Sanchez, Lawrence Steinman   +2 more
wiley   +1 more source

Phillyrin alleviates Kawasaki disease-induced lung inflammation by inhibiting platelet production through the NLRP3/IL-1β/NF-E2 signaling pathway. [PDF]

Chin Med
Mai DH, Huang X, Liang M, Yu X, Hao W, Yang LW, Feng JR, Ling XL, Wang K, Zhu L, Chen Y.   +10 more
europepmc   +1 more source