Results 1 to 10 of about 3,044 (103)

RETRACTED: Neuroprotective Role of L-NG-Nitroarginine Methyl Ester (L-NAME) against Chronic Hypobaric Hypoxia with Crowding Stress (CHC) Induced Depression-Like Behaviour.

PLoS ONE, 2016
Improper neuroimmune responses following chronic stress exposure have been reported to cause neuronal dysfunctions leading to memory impairment, anxiety and depression like behaviours. Though several factors affecting microglial activation and consequent
Satya Narayan Deep, Iswar Baitharu, Apurva Sharma, Anoop Kishor Singh Gurjar, Dipti Prasad, Shashi Bala Singh   +5 more
doaj   +5 more sources

Isosakuranetin ameliorates hypertension in rats induced by L-NAME [PDF]

Journal of Pharmaceutical Health Care and Sciences
Background Hypertension is a major global health problem that often develops without noticeable symptoms. Current treatments and complementary approaches focus on improving endothelial function and enhancing nitric oxide (NO) production to promote ...
Rungusa Pantan, Ratchanaporn Chokchaisiri, Apichart Suksamrarn, Chainarong Tocharus   +3 more
doaj   +2 more sources

Retraction: Neuroprotective Role of L-NG-Nitroarginine Methyl Ester (L-NAME) against Chronic Hypobaric Hypoxia with Crowding Stress (CHC) Induced Depression-Like Behaviour. [PDF]

PLoS ONE
PLOS One Editors
doaj   +3 more sources

Perinatal N(G)-Nitro-L-arginine methyl ester administration decreases anxiety- and depression-like behaviors in adult mice [PDF]

Einstein (São Paulo), 2023
Objective: We hypothesized that perinatal manipulations of the nitrergic system would affect adult animal behaviors. Methods: We tested this hypothesis by perinatally administering N(G)-Nitro-L-arginine methyl ester (L-NAME), a non-specific antagonist ...
Raoni Conceição Dos-Santos, Cláudio da Silva-Almeida, Bruno Guimarães Marinho, Rodrigo Rodrigues da Conceição, Wellington da Silva Côrtes, Ragab Gaber Ahmed, Roberto Laureano-Melo   +6 more
doaj   +1 more source

Physalis angulata leaf extract ameliorates L-NG-nitroarginine methyl ester (L-NAME)-induced preeclampsia symptoms in rats through improved endothelial progenitor cells and endothelial cells due to reduced antiangiogenic factor and oxidative stress

F1000Research, 2022
Background: This study aimed to determine the ameliorative effects of Physalis angulata leaf extract on L-NG-nitroarginine methyl ester (L-NAME)-induced preeclampsia symptoms in rats. Methods: Phytochemical analysis of the extract was performed with liquid chromatography-high resolution mass spectrometry (LC-HRMS).
Dian Nugrahenny, Achmad Rudijanto, Nur Permatasari, I Wayan Arsana Wiyasa, Mohammad Aris Widodo, Karyono Mintaroem, Edi Widjajanto, Mustofa Mustofa   +7 more
openaire   +2 more sources

Effects of oxidative stress on liver, brain and spinal cord of rats using L-NAME and treated with hydroxyurea. A model of sickle cell complication [PDF]

Acta Cirúrgica Brasileira, 2020
Purpose: To analyze the serum levels of nitric oxide and correlate them with the levels of thiobarbituric acid reactive substances (TBARS) in liver, brain and spinal cord of animals using L-NAME and treated with hydroxyurea.
Abilio Torres dos Santos Neto, Iandara Schettert Silva, Maria Lucia Ivo, Camila Tozaki Rodrigues, Eduardo Benedetti Parisotto, Rondon Tosta Ramalho, Geanlucas Mendes Monteiro   +6 more
doaj   +1 more source

The Possible Anti-nociceptive Effect of Troxerutin and Neural Interactions Using Formalin and Writhing Tests in Mice [PDF]

Avicenna Journal of Medical Biochemistry, 2023
Background: Previous reports suggest flavonoids as potent analgesic compounds. Objectives: Based on these observations, the present study investigated the anti-nociceptive action of troxerutin and neural interactions with opioidergic, serotoninergic ...
Farima Jafari-Tirabadi, Shahin Hassanpour, Ahmad Asghari   +2 more
doaj   +1 more source

Effects of L-arginine and L-NAME on ischemia-reperfusion in rat liver [PDF]

Acta Cirúrgica Brasileira, 2015
PURPOSE: To evaluated the effects of L-arginine (a NO donor) and L-NAME (Nw-nitro-L-arginine methyl ester - a NOS inhibitor) on ischemia-reperfusion in rat livers.METHODS: One hundred fifty two male Wistar rats were divided into four groups: control ...
Márcio Luís Lucas, Cláudia Ramos Rhoden, Ernani Luís Rhoden, Cláudio Galeano Zettler, Angelo Alves de Mattos   +4 more
doaj   +1 more source

Tadalafil Improves L-NG-Nitroarginine Methyl Ester-Induced Preeclampsia With Fetal Growth Restriction-Like Symptoms in Pregnant Mice [PDF]

American Journal of Hypertension, 2017
Abstract BACKGROUND We investigated the efficacy and mechanisms of tadalafil, a selective phosphodiesterase 5 inhibitor, in treating preeclampsia (PE) with fetal growth restriction (FGR) using L-NG-nitroarginine methyl ester (L-NAME)-induced PE with FGR in pregnant mice as our experimental model.
Kento, Yoshikawa, Takashi, Umekawa, Shintaro, Maki, Michiko, Kubo, Masafumi, Nii, Kayo, Tanaka, Hiroaki, Tanaka, Kazuhiro, Osato, Yuki, Kamimoto, Eiji, Kondo, Kenji, Ikemura, Masahiro, Okuda, Kan, Katayama, Takekazu, Miyoshi, Hiroshi, Hosoda, Ning, Ma, Toshimichi, Yoshida, Tomoaki, Ikeda   +17 more
openaire   +2 more sources

Effects of nitric oxide synthase inhibitors, l‐N^G‐nitroarginine and l‐N^G‐nitroarginine methyl ester, on responses to vasodilators of the guinea‐pig coronary vasculature [PDF]

British Journal of Pharmacology, 1992
The effects of l‐NG‐nitroarginine (l‐NOARG) and l‐NG‐nitroarginine methyl ester (l‐NAME) on vasodilatation induced by ATP, substance P, 5‐hydroxytryptamine (5‐HT), bradykinin and sodium nitroprusside (SNP) were examined in the guinea‐pig coronary bed, by use of a Langendorff technique.
A, Vials, G, Burnstock
openaire   +2 more sources