Results 31 to 40 of about 3,927 (157)

Perturbations in nitric oxide homeostasis promote Arabidopsis disease susceptibility towards Phytophthora parasitica

Molecular Plant Pathology, Volume 22, Issue 9, Page 1134-1148, September 2021., 2021
Perturbations in Arabidopsis nitric oxide homeostasis promote disease susceptibility towards the oomycete pathogen Phytophthora parasitica. Abstract Phytophthora species can infect hundreds of different plants, including many important crops, causing a number of agriculturally relevant diseases.
Beimi Cui, Xiangren Ma, Yuan Li, Yu Zhou, Xiuyun Ju, Adil Hussain, Saima Umbreen, Bo Yuan, Anika Tabassum, Jibril Lubega, Weixing Shan, Gary J. Loake, Qiaona Pan   +12 more
wiley   +1 more source

Estrogen stimulates dimethylarginine dimethylaminohydrolase activity and the metabolism of asymmetric dimethylarginine. [PDF]

, 2003
Background— Experimental evidence suggests that estrogens stimulate the production of nitric oxide (NO) by vascular endothelial cells. This effect has been attributed to increased expression and enzymatic activity of both the constitutive and inducible ...
Cartwright, JE, Holden, DP, Nussey, SS, Whitley, GS   +3 more
core   +1 more source

Gallic Acid Attenuates Angiotensin II-Induced Hypertension and Vascular Dysfunction by Inhibiting the Degradation of Endothelial Nitric Oxide Synthase

Frontiers in Pharmacology, 2020
Hypertension is a major cause of heart attack and stroke. Our recent study revealed that gallic acid (GA) exerts protective effects on pressure overload-induced cardiac hypertrophy and dysfunction.
Xiao Yan, Qi-Yu Zhang, Yun-Long Zhang, Xiao Han, Shu-Bin Guo, Hui-Hua Li, Hui-Hua Li   +6 more
doaj   +1 more source

Quercetin relaxes human gastric smooth muscles directly through ATP‐sensitive potassium channels and not depending on the nitric oxide pathway

Neurogastroenterology &Motility, Volume 33, Issue 7, July 2021., 2021
Certain gastric smooth muscle relaxation pathways and their selective inhibitors. Abstract Background Quercetin has recently become a remarkably popular subject of research due to its broad beneficial pharmacological properties. The goal of our study was to observe its effects on contractility of human gastric smooth muscles in reference to the NO ...
Beata Modzelewska, Krzysztof Drygalski, Tomasz Kleszczewski, Andrzej Chomentowski, Krzysztof Koryciński, Aleksandra Kiełczewska, Patrycja Pawłuszewicz, Hady Razak Hady   +7 more
wiley   +1 more source

Revisiting the expression and function of follicle-stimulation hormone receptor in human umbilical vein endothelial cells [PDF]

, 2016
Expression of follicle-stimulation hormone receptor (FSHR) is confined to gonads and at low levels to some extragonadal tissues like human umbilical vein endothelial cells (HUVEC). FSH-FSHR signaling was shown to promote HUVEC angiogenesis and thereafter
Akerfelt, Malin, Chrusciel, Marcin, Doroszko, Milena, Frentsch, Marco, Huhtaniemi, Ilpo, Kero, Jukka, Li, Xiangdong, Nees, Matthias, Ponikwicka-Tyszko, Donata, Rahman, Nafis A., Stelmaszewska, Joanna, Wolczynski, Slawomir   +11 more
core   +1 more source

Proteolytic activity of Triatoma infestans saliva associated with PAR-2 activation and vasodilation [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2021
Background Triatoma infestans (Hemiptera: Reduviidae) is a hematophagous insect and the main vector of Trypanosoma cruzi (Kinetoplastida: Trypanosomatidae). In the present study, the authors investigated whether a serine protease activity from the saliva
Karla A. Oliveira, Ricardo J. S. Torquato, Daniela C. G. Garcia Lustosa, Tales Ribeiro, Bruno W. L. Nascimento, Lilian C. G. de Oliveira, Maria A. Juliano, Thaysa Paschoalin, Virginia S. Lemos, Ricardo N. Araujo, Marcos H. Pereira, Aparecida S. Tanaka   +11 more
doaj   +1 more source

Short-Term Administration of Serelaxin Produces Predominantly Vascular Benefits in the Angiotensin II/L-NAME Chronic Heart Failure Model

JACC: Basic to Translational Science, 2017
Summary: In patients hospitalized with acute heart failure, temporary serelaxin infusion reduced 6-month mortality through unknown mechanisms. This study therefore explored the cardiovascular effects of temporary serelaxin administration in mice ...
Joseph C. McCarthy, MS, Mark Aronovitz, MS, Jennifer J. DuPont, PhD, Timothy D. Calamaras, PhD, Iris Z. Jaffe, MD, PhD, Robert M. Blanton, MD   +5 more
doaj   +1 more source

Maternal tadalafil therapy for fetal growth restriction prevents non-alcoholic fatty liver disease and adipocyte hypertrophy in the offspring

Scientific Reports, 2021
We aimed to investigate the effects of maternal tadalafil therapy on fetal programming of metabolic function in a mouse model of fetal growth restriction (FGR). Pregnant C57BL6 mice were divided into the control, L-NG-nitroarginine methyl ester (L-NAME),
Takuya Kawamura, Hiroaki Tanaka, Ryota Tachibana, Kento Yoshikawa, Shintaro Maki, Kuniaki Toriyabe, Hiroki Takeuchi, Shinji Katsuragi, Kayo Tanaka, Tomoaki Ikeda   +9 more
doaj   +1 more source

Alamandine and Its Receptor MrgD Pair Up to Join the Protective Arm of the Renin-Angiotensin System [PDF]

, 2019
Only a few years ago, alamandine was found to be a member of the protective arm of the renin-angiotensin system. It turned out to be an endogenous ligand of the G protein-coupled receptor MrgD.
Schleifenbaum, Johanna
core   +1 more source

Participation of NO in the vasodilatory action of isoespintanol

Vitae, 2019
Background: accumulating evidence suggests that natural compounds and specifically monoterpenes exert a vasodilator action. Objetive: to investigate the vascular effects of isoespintanol (2-isopropil-3,6- dimetoxi-5-metilfenol, ISO) monoterpene isolated ...
Gustavo J. RINALDI, Benjamín ROJANO, Guillermo SCHINELLA, Susana M. MOSCA   +3 more
doaj   +1 more source